CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.420 | Nucleotidyltransferase; domain 5 |
|
3.30.420.40 | ATPase, nucleotide binding domain |
Domain Context
CATH Clusters
| Superfamily | 3.30.420.40 |
| Functional Family | Glycerol kinase |
Enzyme Information
| 2.7.1.30 |
Glycerol kinase.
based on mapping to UniProt P0A6F3
ATP + glycerol = ADP + sn-glycerol 3-phosphate.
-!- Glycerone and L-glyceraldehyde can act as acceptors. -!- UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors.
|
UniProtKB Entries (1)
| P0A6F3 |
GLPK_ECOLI
Escherichia coli K-12
Glycerol kinase
|
PDB Structure
| PDB | 1BWF |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structures of Escherichia coli glycerol kinase variant S58-->W in complex with nonhydrolyzable ATP analogues reveal a putative active conformation of the enzyme as a result of domain motion.
Biochemistry
|
