×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

1 keywords

CATH Domain 1b9lH00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.1130 GTP Cyclohydrolase I, domain 2
Homologous Superfamily 3.30.1130.10 GTP cyclohydrolase I, C-terminal domain/NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal domain

Domain Context

CATH Clusters

Superfamily 3.30.1130.10
Functional Family D-erythro-7,8-dihydroneopterin triphosphate epimerase

Enzyme Information

5.1.99.7
Dihydroneopterin triphosphate 2'-epimerase.
based on mapping to UniProt P0AC19
7,8-dihydroneopterin 3'-triphosphate = 7,8-dihydromonapterin 3'-triphosphate.
-!- The enzyme, found in gammaproteobacteria, has almost no activity with 7,8-dihydroneopterin.

UniProtKB Entries (1)

P0AC19
FOLX_ECOLI
Escherichia coli K-12
Dihydroneopterin triphosphate 2'-epimerase

PDB Structure

PDB 1B9L
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of 7,8-dihydroneopterin triphosphate epimerase.
Ploom, T., Haussmann, C., Hof, P., Steinbacher, S., Bacher, A., Richardson, J., Huber, R.
Structure Fold.Des.
CATH-Gene3D is a Global Biodata Core Resource Learn more...