CATH Domain 1aqcB00

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.30	Roll
	2.30.29	PH-domain like
	2.30.29.30	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Domain Context

CATH Clusters

Superfamily	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family	amyloid beta A4 precursor protein-binding family A member 1

Enzyme Information

UniProtKB Entries (1)

APBA1_HUMAN

Homo sapiens

Amyloid-beta A4 precursor protein-binding family A member 1

PDB Structure

PDB	1AQC
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain. Zhang, Z., Lee, C.H., Mandiyan, V., Borg, J.P., Margolis, B., Schlessinger, J., Kuriyan, J. EMBO J.