CATH Domain 1an1E01

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily	Trypsin-like serine proteases
Functional Family	Anionic trypsin-2

Enzyme Information

3.4.21.4

Trypsin.

based on mapping to UniProt P00761

Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.

-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.4.

UniProtKB Entries (2)

P80424	LDTI_HIRME Hirudo medicinalis Leech-derived tryptase inhibitor C
P00761	TRYP_PIG Sus scrofa Trypsin

PDB Structure

PDB	1AN1
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Saccharomyces
Primary Citation	Structure of the complex of leech-derived tryptase inhibitor (LDTI) with trypsin and modeling of the LDTI-tryptase system. Di Marco, S., Priestle, J.P. Structure