The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
succinate dehydrogenase protein domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Succinate dehydrogenase [ubiquinone] flavoprotein ...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 14 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Succinate dehydrogenase (ubiquinone) activity GO:0008177
Catalysis of the reaction: succinate + ubiquinone = fumarate + ubiquinol.
19 P47052 (/ISS) P47052 (/ISS) P47052 (/ISS) P47052 (/ISS) P47052 (/ISS) Q8IJ66 (/ISS) Q8IJ66 (/ISS) Q8IJ66 (/ISS) Q8IJ66 (/ISS) Q8IJ66 (/ISS)
(9 more)
Succinate dehydrogenase (ubiquinone) activity GO:0008177
Catalysis of the reaction: succinate + ubiquinone = fumarate + ubiquinol.
9 P47052 (/IGI) P47052 (/IGI) P47052 (/IGI) P47052 (/IGI) P47052 (/IGI) Q00711 (/IGI) Q00711 (/IGI) Q00711 (/IGI) Q00711 (/IGI)
Succinate dehydrogenase (ubiquinone) activity GO:0008177
Catalysis of the reaction: succinate + ubiquinone = fumarate + ubiquinol.
9 P47052 (/IMP) P47052 (/IMP) P47052 (/IMP) P47052 (/IMP) P47052 (/IMP) Q00711 (/IMP) Q00711 (/IMP) Q00711 (/IMP) Q00711 (/IMP)
Succinate dehydrogenase activity GO:0000104
Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor.
4 Q4QAG8 (/ISM) Q57TV5 (/ISM) Q57TV5 (/ISM) Q57TV5 (/ISM)
Succinate dehydrogenase activity GO:0000104
Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor.
4 O82663 (/TAS) O82663 (/TAS) Q9ZPX5 (/TAS) Q9ZPX5 (/TAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 Q00711 (/IPI) Q00711 (/IPI) Q00711 (/IPI) Q00711 (/IPI)
Succinate dehydrogenase (ubiquinone) activity GO:0008177
Catalysis of the reaction: succinate + ubiquinone = fumarate + ubiquinol.
4 Q00711 (/IDA) Q00711 (/IDA) Q00711 (/IDA) Q00711 (/IDA)
Flavin adenine dinucleotide binding GO:0050660
Interacting selectively and non-covalently with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.
4 Q00711 (/IDA) Q00711 (/IDA) Q00711 (/IDA) Q00711 (/IDA)
Flavin adenine dinucleotide binding GO:0050660
Interacting selectively and non-covalently with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.
4 Q00711 (/IMP) Q00711 (/IMP) Q00711 (/IMP) Q00711 (/IMP)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
2 O82663 (/IDA) O82663 (/IDA)
Cobalt ion binding GO:0050897
Interacting selectively and non-covalently with a cobalt (Co) ion.
2 O82663 (/IDA) O82663 (/IDA)
Succinate dehydrogenase activity GO:0000104
Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor.
1 Q608E2 (/ISS)
Succinate dehydrogenase activity GO:0000104
Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor.
1 C8VJ65 (/RCA)
Flavin adenine dinucleotide binding GO:0050660
Interacting selectively and non-covalently with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.
1 Q9UTJ7 (/ISM)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Tricarboxylic acid cycle GO:0006099
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
15 Q608E2 (/ISS) Q8IJ66 (/ISS) Q8IJ66 (/ISS) Q8IJ66 (/ISS) Q8IJ66 (/ISS) Q8IJ66 (/ISS) Q8IJ66 (/ISS) Q8IJ66 (/ISS) Q8IJ66 (/ISS) Q8IJ66 (/ISS)
(5 more)
Cellular respiration GO:0045333
The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration).
9 P47052 (/IGI) P47052 (/IGI) P47052 (/IGI) P47052 (/IGI) P47052 (/IGI) Q00711 (/IGI) Q00711 (/IGI) Q00711 (/IGI) Q00711 (/IGI)
Cellular respiration GO:0045333
The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration).
9 P47052 (/IMP) P47052 (/IMP) P47052 (/IMP) P47052 (/IMP) P47052 (/IMP) Q00711 (/IMP) Q00711 (/IMP) Q00711 (/IMP) Q00711 (/IMP)
Tricarboxylic acid cycle GO:0006099
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
4 Q00711 (/IC) Q00711 (/IC) Q00711 (/IC) Q00711 (/IC)
Tricarboxylic acid cycle GO:0006099
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
4 Q4QAG8 (/ISM) Q57TV5 (/ISM) Q57TV5 (/ISM) Q57TV5 (/ISM)
Mitochondrial electron transport, succinate to ubiquinone GO:0006121
The transfer of electrons from succinate to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex II.
4 Q00711 (/IDA) Q00711 (/IDA) Q00711 (/IDA) Q00711 (/IDA)
Mitochondrial electron transport, succinate to ubiquinone GO:0006121
The transfer of electrons from succinate to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex II.
4 O82663 (/TAS) O82663 (/TAS) Q9ZPX5 (/TAS) Q9ZPX5 (/TAS)
Mitochondrial electron transport, succinate to ubiquinone GO:0006121
The transfer of electrons from succinate to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex II.
2 Q9U3X4 (/ISS) Q9UTJ7 (/ISS)
Tricarboxylic acid cycle GO:0006099
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
1 C8VJ65 (/RCA)
Succinate metabolic process GO:0006105
The chemical reactions and pathways involving succinate, also known as butanedioate or ethane dicarboxylate, the dianion of succinic acid. Succinate is an important intermediate in metabolism and a component of the TCA cycle.
1 Q9UTJ7 (/IC)
Positive phototaxis GO:0046956
The directed movement of a cell or organism towards a source of light.
1 Q9U3X4 (/IMP)

There are 15 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) GO:0005749
A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain.
19 O82663 (/ISS) O82663 (/ISS) Q8IJ66 (/ISS) Q8IJ66 (/ISS) Q8IJ66 (/ISS) Q8IJ66 (/ISS) Q8IJ66 (/ISS) Q8IJ66 (/ISS) Q8IJ66 (/ISS) Q8IJ66 (/ISS)
(9 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
14 Q8IJ66 (/ISS) Q8IJ66 (/ISS) Q8IJ66 (/ISS) Q8IJ66 (/ISS) Q8IJ66 (/ISS) Q8IJ66 (/ISS) Q8IJ66 (/ISS) Q8IJ66 (/ISS) Q8IJ66 (/ISS) Q8IJ66 (/ISS)
(4 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
11 O82663 (/IDA) O82663 (/IDA) Q00711 (/IDA) Q00711 (/IDA) Q00711 (/IDA) Q00711 (/IDA) Q57TV5 (/IDA) Q57TV5 (/IDA) Q57TV5 (/IDA) Q9ZPX5 (/IDA)
(1 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
10 P47052 (/HDA) P47052 (/HDA) P47052 (/HDA) P47052 (/HDA) P47052 (/HDA) Q00711 (/HDA) Q00711 (/HDA) Q00711 (/HDA) Q00711 (/HDA) Q9UTJ7 (/HDA)
Respiratory chain complex II GO:0045273
A part of the respiratory chain, containing the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain.
10 O82663 (/IDA) O82663 (/IDA) Q6ZDY8 (/IDA) Q6ZDY8 (/IDA) Q6ZDY8 (/IDA) Q6ZDY8 (/IDA) Q6ZDY8 (/IDA) Q6ZDY8 (/IDA) Q9ZPX5 (/IDA) Q9ZPX5 (/IDA)
Mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) GO:0005749
A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain.
6 O82663 (/IDA) O82663 (/IDA) Q00711 (/IDA) Q00711 (/IDA) Q00711 (/IDA) Q00711 (/IDA)
Contractile vacuole GO:0000331
A specialized vacuole of eukaryotic cells, especially Protozoa, that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores. Its function is probably osmoregulatory.
4 Q4QAG8 (/ISO) Q57TV5 (/ISO) Q57TV5 (/ISO) Q57TV5 (/ISO)
Mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) GO:0005749
A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain.
4 Q00711 (/IMP) Q00711 (/IMP) Q00711 (/IMP) Q00711 (/IMP)
Mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) GO:0005749
A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain.
4 Q4QAG8 (/ISO) Q57TV5 (/ISO) Q57TV5 (/ISO) Q57TV5 (/ISO)
Mitochondrial membrane GO:0031966
Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.
4 Q00711 (/IDA) Q00711 (/IDA) Q00711 (/IDA) Q00711 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 Q57TV5 (/IDA) Q57TV5 (/IDA) Q57TV5 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
3 Q57TV5 (/RCA) Q57TV5 (/RCA) Q57TV5 (/RCA)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
2 O82663 (/IDA) O82663 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q4QAG8 (/ISO)
Phagocytic vesicle GO:0045335
A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
1 Q9U3X4 (/HDA)