The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Endothelial cell-specific molecule 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Hepatocyte growth factor receptor binding GO:0005171
Interacting selectively and non-covalently with the hepatocyte growth factor receptor.
4 Q9NQ30 (/IPI) Q9NQ30 (/IPI) Q9NQ30 (/IPI) Q9NQ30 (/IPI)
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
4 Q9NQ30 (/IPI) Q9NQ30 (/IPI) Q9NQ30 (/IPI) Q9NQ30 (/IPI)
Hepatocyte growth factor receptor binding GO:0005171
Interacting selectively and non-covalently with the hepatocyte growth factor receptor.
2 Q9QYY7 (/ISO) Q9QYY7 (/ISO)
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
2 Q9QYY7 (/ISO) Q9QYY7 (/ISO)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Angiogenesis GO:0001525
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
4 Q9NQ30 (/IEP) Q9NQ30 (/IEP) Q9NQ30 (/IEP) Q9NQ30 (/IEP)
Sprouting angiogenesis GO:0002040
The extension of new blood vessels from existing vessels into avascular tissues, this process includes the specialization of endothelial cells into leading tip and stalk cells, proliferation and migration of the endothelial cells and cell adhesion resulting in angiogenic sprout fusion or lumen formation.
4 Q9NQ30 (/IMP) Q9NQ30 (/IMP) Q9NQ30 (/IMP) Q9NQ30 (/IMP)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
4 Q9NQ30 (/IDA) Q9NQ30 (/IDA) Q9NQ30 (/IDA) Q9NQ30 (/IDA)
Positive regulation of hepatocyte growth factor receptor signaling pathway GO:1902204
Any process that activates or increases the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway.
4 Q9NQ30 (/IDA) Q9NQ30 (/IDA) Q9NQ30 (/IDA) Q9NQ30 (/IDA)
Sprouting angiogenesis GO:0002040
The extension of new blood vessels from existing vessels into avascular tissues, this process includes the specialization of endothelial cells into leading tip and stalk cells, proliferation and migration of the endothelial cells and cell adhesion resulting in angiogenic sprout fusion or lumen formation.
2 Q9QYY7 (/ISO) Q9QYY7 (/ISO)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
2 Q9QYY7 (/ISO) Q9QYY7 (/ISO)
Positive regulation of hepatocyte growth factor receptor signaling pathway GO:1902204
Any process that activates or increases the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway.
2 Q9QYY7 (/ISO) Q9QYY7 (/ISO)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
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