CATH Superfamily 4.10.320.30
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 2: Histone acetyltransferase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
25 |
O95251 (/ISA)
O95251 (/ISA)
O95251 (/ISA)
O95251 (/ISA)
O95251 (/ISA)
O95251 (/ISA)
O95251 (/ISA)
O95251 (/ISA)
O95251 (/ISA)
O95251 (/ISA)
(15 more) |
DNA replication origin binding GO:0003688
Interacting selectively and non-covalently with the DNA replication origin, a unique DNA sequence of a replicon at which DNA replication is initiated and proceeds bidirectionally or unidirectionally.
|
25 |
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
(15 more) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
25 |
O95251 (/IPI)
O95251 (/IPI)
O95251 (/IPI)
O95251 (/IPI)
O95251 (/IPI)
O95251 (/IPI)
O95251 (/IPI)
O95251 (/IPI)
O95251 (/IPI)
O95251 (/IPI)
(15 more) |
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
|
25 |
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
(15 more) |
DNA replication origin binding GO:0003688
Interacting selectively and non-covalently with the DNA replication origin, a unique DNA sequence of a replicon at which DNA replication is initiated and proceeds bidirectionally or unidirectionally.
|
1 | Q5SVQ0 (/ISO) |
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
|
1 | Q5SVQ0 (/ISO) |
There are 38 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
DNA replication GO:0006260
The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
|
25 |
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
(15 more) |
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
25 |
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
(15 more) |
Internal peptidyl-lysine acetylation GO:0018393
The addition of an acetyl group to a non-terminal lysine residue in a protein.
|
25 |
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
(15 more) |
Stress-activated protein kinase signaling cascade GO:0031098
A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals.
|
25 |
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
(15 more) |
Histone H3 acetylation GO:0043966
The modification of histone H3 by the addition of an acetyl group.
|
25 |
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
(15 more) |
Histone H4-K5 acetylation GO:0043981
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 5 of the histone.
|
25 |
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
(15 more) |
Histone H4-K8 acetylation GO:0043982
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 8 of the histone.
|
25 |
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
(15 more) |
Histone H4-K12 acetylation GO:0043983
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 12 of the histone.
|
25 |
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
(15 more) |
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
25 |
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
(15 more) |
Response to sorbitol GO:0072708
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sorbitol stimulus.
|
25 |
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
(15 more) |
Response to hydroxyurea GO:0072710
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus.
|
25 |
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
(15 more) |
Response to actinomycin D GO:0072716
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus.
|
25 |
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
(15 more) |
Response to dithiothreitol GO:0072720
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dithiothreitol stimulus.
|
25 |
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
(15 more) |
Response to anisomycin GO:0072739
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anisomycin stimulus.
|
25 |
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
(15 more) |
Positive regulation of histone H4 acetylation GO:0090240
Any process that increases the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group.
|
25 |
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
(15 more) |
Positive regulation of protein localization to nucleus GO:1900182
Any process that activates or increases the frequency, rate or extent of protein localization to nucleus.
|
25 |
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
(15 more) |
DNA replication GO:0006260
The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
|
2 | Q5SVQ0 (/ISS) Q810T5 (/ISS) |
Internal peptidyl-lysine acetylation GO:0018393
The addition of an acetyl group to a non-terminal lysine residue in a protein.
|
2 | Q5SVQ0 (/ISS) Q810T5 (/ISS) |
Histone H3 acetylation GO:0043966
The modification of histone H3 by the addition of an acetyl group.
|
2 | Q5SVQ0 (/ISS) Q810T5 (/ISS) |
Histone H4-K5 acetylation GO:0043981
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 5 of the histone.
|
2 | Q5SVQ0 (/ISS) Q810T5 (/ISS) |
Histone H4-K8 acetylation GO:0043982
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 8 of the histone.
|
2 | Q5SVQ0 (/ISS) Q810T5 (/ISS) |
Histone H4-K12 acetylation GO:0043983
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 12 of the histone.
|
2 | Q5SVQ0 (/ISS) Q810T5 (/ISS) |
Blood vessel development GO:0001568
The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.
|
1 | Q7ZW29 (/IMP) |
DNA replication GO:0006260
The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
|
1 | Q5SVQ0 (/ISO) |
Internal peptidyl-lysine acetylation GO:0018393
The addition of an acetyl group to a non-terminal lysine residue in a protein.
|
1 | Q5SVQ0 (/ISO) |
Stress-activated protein kinase signaling cascade GO:0031098
A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals.
|
1 | Q5SVQ0 (/ISO) |
Histone H3 acetylation GO:0043966
The modification of histone H3 by the addition of an acetyl group.
|
1 | Q5SVQ0 (/ISO) |
Histone H4-K5 acetylation GO:0043981
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 5 of the histone.
|
1 | Q5SVQ0 (/ISO) |
Histone H4-K8 acetylation GO:0043982
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 8 of the histone.
|
1 | Q5SVQ0 (/ISO) |
Histone H4-K12 acetylation GO:0043983
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 12 of the histone.
|
1 | Q5SVQ0 (/ISO) |
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q5SVQ0 (/ISO) |
Response to sorbitol GO:0072708
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sorbitol stimulus.
|
1 | Q5SVQ0 (/ISO) |
Response to hydroxyurea GO:0072710
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus.
|
1 | Q5SVQ0 (/ISO) |
Response to actinomycin D GO:0072716
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus.
|
1 | Q5SVQ0 (/ISO) |
Response to dithiothreitol GO:0072720
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dithiothreitol stimulus.
|
1 | Q5SVQ0 (/ISO) |
Response to anisomycin GO:0072739
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anisomycin stimulus.
|
1 | Q5SVQ0 (/ISO) |
Positive regulation of histone H4 acetylation GO:0090240
Any process that increases the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group.
|
1 | Q5SVQ0 (/ISO) |
Positive regulation of protein localization to nucleus GO:1900182
Any process that activates or increases the frequency, rate or extent of protein localization to nucleus.
|
1 | Q5SVQ0 (/ISO) |
There are 11 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
29 |
E7EUP3 (/IDA)
E7EUP3 (/IDA)
E7EUP3 (/IDA)
E7EUP3 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
(19 more) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
29 |
E7EUP3 (/IDA)
E7EUP3 (/IDA)
E7EUP3 (/IDA)
E7EUP3 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
(19 more) |
Histone acetyltransferase complex GO:0000123
A protein complex that possesses histone acetyltransferase activity.
|
25 |
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
(15 more) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
25 |
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
(15 more) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
25 |
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
(15 more) |
Histone acetyltransferase complex GO:0000123
A protein complex that possesses histone acetyltransferase activity.
|
2 | Q5SVQ0 (/ISS) Q810T5 (/ISS) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
2 | Q5SVQ0 (/ISS) Q810T5 (/ISS) |
Histone acetyltransferase complex GO:0000123
A protein complex that possesses histone acetyltransferase activity.
|
1 | Q5SVQ0 (/ISO) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q5SVQ0 (/ISO) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q5SVQ0 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q5SVQ0 (/ISO) |