The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Inorganic pyrophosphatase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Pyrophosphatase (inorganic) 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Inorganic diphosphatase activity GO:0004427
Catalysis of the reaction: diphosphate + H(2)O = H(+) + 2 phosphate.
3 Q9H2U2 (/IDA) Q9H2U2 (/IDA) Q9H2U2 (/IDA)
Inorganic diphosphatase activity GO:0004427
Catalysis of the reaction: diphosphate + H(2)O = H(+) + 2 phosphate.
2 Q15181 (/TAS) Q15181 (/TAS)
Pyrophosphatase activity GO:0016462
Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments.
2 Q9D819 (/IDA) Q9D819 (/IDA)
Inorganic diphosphatase activity GO:0004427
Catalysis of the reaction: diphosphate + H(2)O = H(+) + 2 phosphate.
1 Q91VM9 (/ISO)
Protein serine/threonine phosphatase activity GO:0004722
Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
1 Q91VM9 (/IDA)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
TRNA aminoacylation for protein translation GO:0006418
The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, to be used in ribosome-mediated polypeptide synthesis.
5 Q15181 (/TAS) Q15181 (/TAS) Q9H2U2 (/TAS) Q9H2U2 (/TAS) Q9H2U2 (/TAS)
Diphosphate metabolic process GO:0071344
The chemical reactions and pathways involving diphosphate, the anion or salt of diphosphoric acid.
5 Q15181 (/TAS) Q15181 (/TAS) Q9H2U2 (/TAS) Q9H2U2 (/TAS) Q9H2U2 (/TAS)
Regulation of mitochondrial membrane potential GO:0051881
Any process that modulates the establishment or extent of the mitochondrial membrane potential, the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
3 Q9H2U2 (/IMP) Q9H2U2 (/IMP) Q9H2U2 (/IMP)
Phosphate-containing compound metabolic process GO:0006796
The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
2 Q9D819 (/IC) Q9D819 (/IC)
Phosphate-containing compound metabolic process GO:0006796
The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
2 Q15181 (/TAS) Q15181 (/TAS)
Regulation of mitochondrial membrane potential GO:0051881
Any process that modulates the establishment or extent of the mitochondrial membrane potential, the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
1 Q91VM9 (/ISO)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
3 Q9H2U2 (/TAS) Q9H2U2 (/TAS) Q9H2U2 (/TAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q15181 (/TAS) Q15181 (/TAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q15181 (/TAS) Q15181 (/TAS)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
2 Q15181 (/HDA) Q15181 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q91VM9 (/HDA)
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