The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Nucleoside Triphosphate Pyrophosphohydrolase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 12: Isopentenyl-diphosphate Delta-isomerase 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Isopentenyl-diphosphate delta-isomerase activity GO:0004452
Catalysis of the reaction: isopentenyl diphosphate = dimethylallyl diphosphate.
11 P15496 (/IDA) P15496 (/IDA) P15496 (/IDA) P15496 (/IDA) P15496 (/IDA) P15496 (/IDA) P15496 (/IDA) P15496 (/IDA) P15496 (/IDA) Q10132 (/IDA)
(1 more)
Isopentenyl-diphosphate delta-isomerase activity GO:0004452
Catalysis of the reaction: isopentenyl diphosphate = dimethylallyl diphosphate.
3 G5EB72 (/RCA) G5EB72 (/RCA) G5EB72 (/RCA)
Isopentenyl-diphosphate delta-isomerase activity GO:0004452
Catalysis of the reaction: isopentenyl diphosphate = dimethylallyl diphosphate.
2 P58044 (/ISO) Q8BFZ6 (/ISO)
Isopentenyl-diphosphate delta-isomerase activity GO:0004452
Catalysis of the reaction: isopentenyl diphosphate = dimethylallyl diphosphate.
2 Q8MRH1 (/ISS) Q9VDC2 (/ISS)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
1 P58044 (/ISO)
Isopentenyl-diphosphate delta-isomerase activity GO:0004452
Catalysis of the reaction: isopentenyl diphosphate = dimethylallyl diphosphate.
1 O35760 (/TAS)
Manganese ion binding GO:0030145
Interacting selectively and non-covalently with manganese (Mn) ions.
1 P58044 (/ISO)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Farnesyl diphosphate biosynthetic process GO:0045337
The chemical reactions and pathways resulting in the formation of farnesyl diphosphate.
9 P15496 (/IDA) P15496 (/IDA) P15496 (/IDA) P15496 (/IDA) P15496 (/IDA) P15496 (/IDA) P15496 (/IDA) P15496 (/IDA) P15496 (/IDA)
Cholesterol biosynthetic process GO:0006695
The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
4 O35760 (/TAS) Q13907 (/TAS) Q13907 (/TAS) Q9BXS1 (/TAS)
Sterol metabolic process GO:0016125
The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
3 G5EB72 (/RCA) G5EB72 (/RCA) G5EB72 (/RCA)
Isoprenoid biosynthetic process GO:0008299
The chemical reactions and pathways resulting in the formation of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
2 Q8MRH1 (/ISS) Q9VDC2 (/ISS)
Regulation of cholesterol biosynthetic process GO:0045540
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
2 Q13907 (/TAS) Q13907 (/TAS)
Isoprenoid biosynthetic process GO:0008299
The chemical reactions and pathways resulting in the formation of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
1 Q9BXS1 (/IDA)
Isoprenoid biosynthetic process GO:0008299
The chemical reactions and pathways resulting in the formation of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
1 P58044 (/ISO)
Response to stilbenoid GO:0035634
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to a stilbenoid. Stilbenoids are secondary products of heartwood formation in trees that can act as phytoalexins. Stilbenoids are hydroxylated derivatives of stilbene. They belong to the family of phenylpropanoids and share most of their biosynthesis pathway with chalcones.
1 P58044 (/IEP)
Farnesyl diphosphate biosynthetic process GO:0045337
The chemical reactions and pathways resulting in the formation of farnesyl diphosphate.
1 Q10132 (/ISO)
Negative regulation of cholesterol biosynthetic process GO:0045541
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
1 Q8BFZ6 (/IDA)
Negative regulation of cholesterol biosynthetic process GO:0045541
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
1 Q8BFZ6 (/IMP)
Isopentenyl diphosphate metabolic process GO:0046490
The chemical reactions and pathways involving isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids.
1 Q9BXS1 (/IDA)
Isopentenyl diphosphate metabolic process GO:0046490
The chemical reactions and pathways involving isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids.
1 Q8BFZ6 (/ISO)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
10 P15496 (/HDA) P15496 (/HDA) P15496 (/HDA) P15496 (/HDA) P15496 (/HDA) P15496 (/HDA) P15496 (/HDA) P15496 (/HDA) P15496 (/HDA) Q10132 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
10 P15496 (/HDA) P15496 (/HDA) P15496 (/HDA) P15496 (/HDA) P15496 (/HDA) P15496 (/HDA) P15496 (/HDA) P15496 (/HDA) P15496 (/HDA) Q10132 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
9 P15496 (/HDA) P15496 (/HDA) P15496 (/HDA) P15496 (/HDA) P15496 (/HDA) P15496 (/HDA) P15496 (/HDA) P15496 (/HDA) P15496 (/HDA)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
5 O35586 (/IDA) O35760 (/IDA) Q13907 (/IDA) Q13907 (/IDA) Q9BXS1 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 Q13907 (/TAS) Q13907 (/TAS) Q9BXS1 (/TAS)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
2 P58044 (/ISO) Q8BFZ6 (/ISO)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
2 Q8MRH1 (/ISS) Q9VDC2 (/ISS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 P58044 (/HDA)
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