The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Protein tyrosine phosphatase superfamily
".
FunFam 60: Phosphatidylglycerophosphatase and protein-tyrosin...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity GO:0004439
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate.
|
2 | Q66GT5 (/IDA) Q86IG3 (/IDA) |
|
Phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity GO:0004439
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate.
|
2 | Q86BN8 (/ISS) Q86BN8 (/ISS) |
|
Phosphatidylglycerophosphatase activity GO:0008962
Catalysis of the reaction: phosphatidylglycerophosphate + H2O = phosphatidylglycerol + phosphate.
|
2 | P0C089 (/ISS) Q8WUK0 (/ISS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q8WUK0 (/IPI) |
|
Phosphatidylglycerophosphatase activity GO:0008962
Catalysis of the reaction: phosphatidylglycerophosphate + H2O = phosphatidylglycerol + phosphate.
|
1 | Q66GT5 (/EXP) |
|
Phosphatidylglycerophosphatase activity GO:0008962
Catalysis of the reaction: phosphatidylglycerophosphate + H2O = phosphatidylglycerol + phosphate.
|
1 | Q66GT5 (/IMP) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Dephosphorylation GO:0016311
The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.
|
2 | Q86BN8 (/ISS) Q86BN8 (/ISS) |
|
Cardiolipin biosynthetic process GO:0032049
The chemical reactions and pathways resulting in the formation of cardiolipin, 1,3-bis(3-phosphatidyl)glycerol.
|
2 | P0C089 (/ISS) Q8WUK0 (/ISS) |
|
Cardiolipin biosynthetic process GO:0032049
The chemical reactions and pathways resulting in the formation of cardiolipin, 1,3-bis(3-phosphatidyl)glycerol.
|
1 | Q66GT5 (/IMP) |
|
Phosphatidylinositol metabolic process GO:0046488
The chemical reactions and pathways involving phosphatidylinositol, any glycophospholipid in which a sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
|
1 | Q66GT5 (/IC) |
|
Inositol phosphate dephosphorylation GO:0046855
The process of removing a phosphate group from any mono- or polyphosphorylated inositol.
|
1 | Q86IG3 (/IDA) |
|
Negative regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061179
Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
|
1 | P0C089 (/IMP) |
|
Negative regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061179
Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
|
1 | Q66GT5 (/ISO) |
|
Regulation of intrinsic apoptotic signaling pathway GO:2001242
Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway.
|
1 | Q8WUK0 (/IGI) |
|
Regulation of intrinsic apoptotic signaling pathway GO:2001242
Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway.
|
1 | Q66GT5 (/ISO) |
There are 9 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | Q86BN8 (/ISS) Q86BN8 (/ISS) |
|
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
|
1 | Q86IG3 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q8WUK0 (/HDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | Q66GT5 (/HDA) |
|
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
1 | Q66GT5 (/ISO) |
|
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
1 | Q66GT5 (/ISS) |
|
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
1 | Q66GT5 (/TAS) |
|
Integral component of mitochondrial inner membrane GO:0031305
The component of the mitochondrial inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | P0C089 (/IDA) |
|
Integral component of mitochondrial inner membrane GO:0031305
The component of the mitochondrial inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q66GT5 (/ISO) |