The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Protein tyrosine phosphatase superfamily
".
FunFam 50: Dual specificity phosphatase 16 (Predicted)
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phosphatase activity GO:0016791
Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
|
6 | Q6PCP3 (/IDA) Q920R2 (/IDA) Q99MG5 (/IDA) Q99MG6 (/IDA) Q9BY84 (/IDA) Q9BY84 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | Q6PCP3 (/IPI) Q920R2 (/IPI) Q99MG5 (/IPI) Q99MG6 (/IPI) |
|
Phosphatase activity GO:0016791
Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
|
4 | Q6PCP3 (/ISO) Q920R2 (/ISO) Q99MG5 (/ISO) Q99MG6 (/ISO) |
|
Phosphoprotein phosphatase activity GO:0004721
Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity.
|
2 | Q9BY84 (/TAS) Q9BY84 (/TAS) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Inactivation of MAPK activity GO:0000188
Any process that terminates the activity of the active enzyme MAP kinase.
|
4 | Q6PCP3 (/IDA) Q920R2 (/IDA) Q99MG5 (/IDA) Q99MG6 (/IDA) |
|
Dephosphorylation GO:0016311
The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.
|
4 | Q6PCP3 (/ISO) Q920R2 (/ISO) Q99MG5 (/ISO) Q99MG6 (/ISO) |
|
Negative regulation of MAPK cascade GO:0043409
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade.
|
4 | Q6PCP3 (/IDA) Q920R2 (/IDA) Q99MG5 (/IDA) Q99MG6 (/IDA) |
|
Inactivation of MAPK activity GO:0000188
Any process that terminates the activity of the active enzyme MAP kinase.
|
2 | Q9BY84 (/TAS) Q9BY84 (/TAS) |
|
Dephosphorylation GO:0016311
The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.
|
2 | Q9BY84 (/IDA) Q9BY84 (/IDA) |
|
Dephosphorylation GO:0016311
The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.
|
2 | Q9BY84 (/TAS) Q9BY84 (/TAS) |
|
MAPK export from nucleus GO:0045204
The directed movement of a MAP kinase from the nucleus to the cytoplasm.
|
2 | Q9BY84 (/TAS) Q9BY84 (/TAS) |
|
MAPK phosphatase export from nucleus, leptomycin B sensitive GO:0045209
Leptomycin B-sensitive movement of a MAPK phosphatase from the nucleus to the cytoplasm.
|
2 | Q9BY84 (/TAS) Q9BY84 (/TAS) |
There are 9 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
5 | D4A3W6 (/IDA) Q6PCP3 (/IDA) Q920R2 (/IDA) Q99MG5 (/IDA) Q99MG6 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
4 | Q6PCP3 (/ISO) Q920R2 (/ISO) Q99MG5 (/ISO) Q99MG6 (/ISO) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
4 | A0A024RAR2 (/IDA) A0A024RAR2 (/IDA) Q9BY84 (/IDA) Q9BY84 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
4 | Q6PCP3 (/ISO) Q920R2 (/ISO) Q99MG5 (/ISO) Q99MG6 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | Q6PCP3 (/IDA) Q920R2 (/IDA) Q99MG5 (/IDA) Q99MG6 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
4 | Q6PCP3 (/ISO) Q920R2 (/ISO) Q99MG5 (/ISO) Q99MG6 (/ISO) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | Q9BY84 (/TAS) Q9BY84 (/TAS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q9BY84 (/TAS) Q9BY84 (/TAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | D4A3W6 (/IDA) |