The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
set domain protein methyltransferase, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: histone-lysine N-methyltransferase setd3 isoform X...

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Protein-histidine N-methyltransferase. [EC: 2.1.1.85]
S-adenosyl-L-methionine + protein L-histidine = S-adenosyl-L-homocysteine + protein N(tau)-methyl-L-histidine.
  • Highly specific for histidine residues, for example, in actin.
19 A0A024R6K3 A0A024R6K3 A9X1D0 B0VX69 B0VX69 B1MTJ4 B2KI88 B5FW36 B7ZUF3 C1FXW2
(9 more...)