The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
DNA Methylase, subunit A, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: tRNA (Cytosine(38)-C(5))-methyltransferase isoform...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
TRNA methyltransferase activity GO:0008175
Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in a tRNA molecule.
2 O14717 (/IDA) O14717 (/IDA)
TRNA methyltransferase activity GO:0008175
Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in a tRNA molecule.
2 O55055 (/IMP) O55055 (/IMP)
TRNA methyltransferase activity GO:0008175
Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in a tRNA molecule.
2 O55055 (/ISO) O55055 (/ISO)
TRNA (cytosine-5-)-methyltransferase activity GO:0016428
Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 5-methylcytosine.
2 O14717 (/EXP) O14717 (/EXP)
TRNA (cytosine-5-)-methyltransferase activity GO:0016428
Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 5-methylcytosine.
2 O55055 (/ISO) O55055 (/ISO)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
TRNA modification GO:0006400
The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.
2 O14717 (/TAS) O14717 (/TAS)
TRNA methylation GO:0030488
The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule.
2 O14717 (/IDA) O14717 (/IDA)
TRNA methylation GO:0030488
The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule.
2 O55055 (/IMP) O55055 (/IMP)
TRNA methylation GO:0030488
The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule.
2 O55055 (/ISO) O55055 (/ISO)
Response to amphetamine GO:0001975
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine.
1 Q4G073 (/IEP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 O14717 (/TAS) O14717 (/TAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 O14717 (/IDA) O14717 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 O55055 (/ISO) O55055 (/ISO)
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