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CATH Superfamily 3.90.1140.10

Cyclic phosphodiesterase

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cyclic phosphodiesterase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9: RNA 2',3'-cyclic phosphodiesterase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
RNA 2',3'-cyclic 3'-phosphodiesterase. [EC: 3.1.4.58]
(Ribonucleotide)(n)-2',3'-cyclic phosphate + H(2)O = (ribonucleotide)(n)- 2'-phosphate.
  • The enzyme hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.
  • In vitro the enzyme can also ligate tRNA molecules with 2',3'-cyclic phosphate to tRNA with 5'-hydroxyl termini, forming a 2'-5' phosphodiester linkage.
  • However, the ligase activity is unlikely to be relevant in vivo.
 11 A0A0F6ALA3 A0A0F6ALA3 A0A0F6ALA3 G4FGQ2 G4FGQ2 G4FGQ2 O66967 Q58963 Q9X2H4 Q9X2H4
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