The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Ribonuclease Inhibitor
".
FunFam 43: Leucine-rich repeat transmembrane protein FLRT3
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | Q8BGT1 (/IPI) Q8BLU0 (/IPI) Q9NZU0 (/IPI) Q9NZU0 (/IPI) |
Protein binding, bridging GO:0030674
The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
|
3 | O43155 (/NAS) Q9NZU0 (/NAS) Q9NZU0 (/NAS) |
Fibroblast growth factor receptor binding GO:0005104
Interacting selectively and non-covalently with the fibroblast growth factor receptor (FGFR).
|
2 | Q8BGT1 (/IPI) Q8BLU0 (/IPI) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
2 | Q70AK3 (/IPI) Q70AK3 (/IPI) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
2 | Q9NZU0 (/IDA) Q9NZU0 (/IDA) |
Chemorepellent activity GO:0045499
Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a lower concentration of that signal.
|
2 | Q8BGT1 (/IDA) Q8BLU0 (/IDA) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | Q8BGT1 (/ISO) |
There are 42 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Fibroblast growth factor receptor signaling pathway GO:0008543
The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.
|
10 | B1H134 (/ISS) B1H234 (/ISS) D3ZTV3 (/ISS) F1NUK7 (/ISS) O43155 (/ISS) Q5R6T0 (/ISS) Q70AK3 (/ISS) Q70AK3 (/ISS) Q9NZU0 (/ISS) Q9NZU0 (/ISS) |
Proepicardium cell migration involved in pericardium morphogenesis GO:0003345
The coordinated movement of a mesenchymal proepicardial cell to the surface of the developing heart.
|
8 | B1H134 (/ISS) B1H234 (/ISS) F1NUK7 (/ISS) Q5R6T0 (/ISS) Q70AK3 (/ISS) Q70AK3 (/ISS) Q9NZU0 (/ISS) Q9NZU0 (/ISS) |
Synapse assembly GO:0007416
The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional).
|
8 | B1H134 (/ISS) B1H234 (/ISS) F1NUK7 (/ISS) Q5R6T0 (/ISS) Q70AK3 (/ISS) Q70AK3 (/ISS) Q9NZU0 (/ISS) Q9NZU0 (/ISS) |
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
8 | B1H134 (/ISS) B1H234 (/ISS) F1NUK7 (/ISS) Q5R6T0 (/ISS) Q70AK3 (/ISS) Q70AK3 (/ISS) Q9NZU0 (/ISS) Q9NZU0 (/ISS) |
Neuron projection development GO:0031175
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
|
8 | B1H134 (/ISS) F1NUK7 (/ISS) Q5R6T0 (/ISS) Q70AK3 (/ISS) Q70AK3 (/ISS) Q8BGT1 (/ISS) Q9NZU0 (/ISS) Q9NZU0 (/ISS) |
Embryonic morphogenesis GO:0048598
The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants.
|
8 | B1H134 (/ISS) B1H234 (/ISS) F1NUK7 (/ISS) Q5R6T0 (/ISS) Q70AK3 (/ISS) Q70AK3 (/ISS) Q9NZU0 (/ISS) Q9NZU0 (/ISS) |
Response to axon injury GO:0048678
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus.
|
8 | B1H134 (/ISS) F1NUK7 (/ISS) Q5R6T0 (/ISS) Q70AK3 (/ISS) Q70AK3 (/ISS) Q8BGT1 (/ISS) Q9NZU0 (/ISS) Q9NZU0 (/ISS) |
Head development GO:0060322
The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body.
|
8 | B1H134 (/ISS) B1H234 (/ISS) F1NUK7 (/ISS) Q5R6T0 (/ISS) Q70AK3 (/ISS) Q70AK3 (/ISS) Q9NZU0 (/ISS) Q9NZU0 (/ISS) |
Neuron projection extension GO:1990138
Long distance growth of a single neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
|
8 | B1H134 (/ISS) F1NUK7 (/ISS) Q5R6T0 (/ISS) Q70AK3 (/ISS) Q70AK3 (/ISS) Q8BGT1 (/ISS) Q9NZU0 (/ISS) Q9NZU0 (/ISS) |
Cell-cell adhesion via plasma-membrane adhesion molecules GO:0098742
The attachment of one cell to another cell via adhesion molecules that are at least partially embedded in the plasma membrane.
|
6 | B1H134 (/ISS) B1H234 (/ISS) F1NUK7 (/ISS) Q5R6T0 (/ISS) Q70AK3 (/ISS) Q70AK3 (/ISS) |
Fibroblast growth factor receptor signaling pathway GO:0008543
The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.
|
3 | O43155 (/TAS) Q9NZU0 (/TAS) Q9NZU0 (/TAS) |
Neuron projection extension GO:1990138
Long distance growth of a single neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
|
3 | B1H234 (/IMP) Q9NZU0 (/IMP) Q9NZU0 (/IMP) |
Heart morphogenesis GO:0003007
The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
2 | D3ZTV3 (/ISS) O43155 (/ISS) |
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
|
2 | B1H234 (/IGI) Q8BLU0 (/IGI) |
Fibroblast growth factor receptor signaling pathway GO:0008543
The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.
|
2 | Q8BGT1 (/IMP) Q8BLU0 (/IMP) |
Neuron projection development GO:0031175
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
|
2 | B1H234 (/IMP) Q8BGT1 (/IMP) |
Positive regulation of synapse assembly GO:0051965
Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
|
2 | Q8BGT1 (/IDA) Q8BLU0 (/IDA) |
Cell adhesion involved in heart morphogenesis GO:0061343
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart.
|
2 | D3ZTV3 (/ISS) O43155 (/ISS) |
Basement membrane organization GO:0071711
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane.
|
2 | D3ZTV3 (/ISS) O43155 (/ISS) |
Cell-cell adhesion via plasma-membrane adhesion molecules GO:0098742
The attachment of one cell to another cell via adhesion molecules that are at least partially embedded in the plasma membrane.
|
2 | Q9NZU0 (/IDA) Q9NZU0 (/IDA) |
Heart morphogenesis GO:0003007
The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
1 | Q8BLU0 (/IMP) |
Proepicardium cell migration involved in pericardium morphogenesis GO:0003345
The coordinated movement of a mesenchymal proepicardial cell to the surface of the developing heart.
|
1 | Q8BGT1 (/IMP) |
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
|
1 | Q8BGT1 (/IMP) |
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
|
1 | Q8BGT1 (/ISO) |
Synapse assembly GO:0007416
The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional).
|
1 | Q8BGT1 (/IMP) |
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
1 | Q8BGT1 (/IMP) |
Neuron projection development GO:0031175
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
|
1 | Q8BGT1 (/ISO) |
Embryonic morphogenesis GO:0048598
The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants.
|
1 | Q8BGT1 (/IMP) |
Response to axon injury GO:0048678
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus.
|
1 | B1H234 (/IMP) |
Response to axon injury GO:0048678
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus.
|
1 | Q8BGT1 (/ISO) |
Synapse organization GO:0050808
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
|
1 | B1H234 (/IMP) |
Synapse organization GO:0050808
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
|
1 | Q8BGT1 (/ISO) |
Head development GO:0060322
The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body.
|
1 | Q8BGT1 (/IMP) |
Cell adhesion involved in heart morphogenesis GO:0061343
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart.
|
1 | Q8BLU0 (/IMP) |
Basement membrane organization GO:0071711
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane.
|
1 | Q8BLU0 (/IMP) |
Cell-cell adhesion via plasma-membrane adhesion molecules GO:0098742
The attachment of one cell to another cell via adhesion molecules that are at least partially embedded in the plasma membrane.
|
1 | Q8BGT1 (/IMP) |
Cell-cell adhesion via plasma-membrane adhesion molecules GO:0098742
The attachment of one cell to another cell via adhesion molecules that are at least partially embedded in the plasma membrane.
|
1 | Q8BGT1 (/ISO) |
Synaptic membrane adhesion GO:0099560
The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane.
|
1 | Q8BGT1 (/IC) |
Synaptic membrane adhesion GO:0099560
The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane.
|
1 | Q8BGT1 (/IDA) |
Synaptic membrane adhesion GO:0099560
The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane.
|
1 | Q8BGT1 (/IMP) |
Neuron projection extension GO:1990138
Long distance growth of a single neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
|
1 | Q8BGT1 (/ISO) |
Regulation of neuron migration GO:2001222
Any process that modulates the frequency, rate or extent of neuron migration.
|
1 | Q8BLU0 (/IGI) |
There are 34 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Axon terminus GO:0043679
Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it.
|
8 | B1H134 (/ISS) F1NUK7 (/ISS) Q5R6T0 (/ISS) Q70AK3 (/ISS) Q70AK3 (/ISS) Q8BGT1 (/ISS) Q9NZU0 (/ISS) Q9NZU0 (/ISS) |
Axonal growth cone GO:0044295
The migrating motile tip of a growing nerve cell axon.
|
8 | B1H134 (/ISS) B1H234 (/ISS) F1NUK7 (/ISS) Q5R6T0 (/ISS) Q70AK3 (/ISS) Q70AK3 (/ISS) Q9NZU0 (/ISS) Q9NZU0 (/ISS) |
Synaptic membrane GO:0097060
A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
|
8 | B1H134 (/ISS) F1NUK7 (/ISS) Q5R6T0 (/ISS) Q70AK3 (/ISS) Q70AK3 (/ISS) Q8BGT1 (/ISS) Q9NZU0 (/ISS) Q9NZU0 (/ISS) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
7 | B1H134 (/ISS) D3ZTV3 (/ISS) F1NUK7 (/ISS) O43155 (/ISS) Q5R6T0 (/ISS) Q70AK3 (/ISS) Q70AK3 (/ISS) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
5 | B1H234 (/IDA) Q8BGT1 (/IDA) Q8BLU0 (/IDA) Q9NZU0 (/IDA) Q9NZU0 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
4 | O43155 (/TAS) Q8BGT1 (/TAS) Q9NZU0 (/TAS) Q9NZU0 (/TAS) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
3 | O43155 (/NAS) Q9NZU0 (/NAS) Q9NZU0 (/NAS) |
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
|
3 | O43155 (/NAS) Q9NZU0 (/NAS) Q9NZU0 (/NAS) |
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
2 | Q8BGT1 (/IDA) Q8BLU0 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | Q9NZU0 (/IDA) Q9NZU0 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | Q9NZU0 (/IDA) Q9NZU0 (/IDA) |
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
|
2 | Q8BGT1 (/IDA) Q8BLU0 (/IDA) |
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
|
2 | D3ZTV3 (/ISS) O43155 (/ISS) |
Cell junction GO:0030054
A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.
|
2 | Q9NZU0 (/IDA) Q9NZU0 (/IDA) |
Integral component of postsynaptic membrane GO:0099055
The component of the postsynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | B1H234 (/IDA) Q8BGT1 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q8BGT1 (/ISO) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q8BGT1 (/ISO) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q8BGT1 (/ISO) |
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
|
1 | O43155 (/HDA) |
Postsynaptic density GO:0014069
An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
|
1 | B1H234 (/IDA) |
Postsynaptic density GO:0014069
An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
|
1 | Q8BGT1 (/ISO) |
Postsynaptic density GO:0014069
An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
|
1 | Q8BGT1 (/ISS) |
Cell junction GO:0030054
A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.
|
1 | Q8BGT1 (/ISO) |
Axon terminus GO:0043679
Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it.
|
1 | B1H234 (/IDA) |
Axon terminus GO:0043679
Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it.
|
1 | Q8BGT1 (/ISO) |
Axonal growth cone GO:0044295
The migrating motile tip of a growing nerve cell axon.
|
1 | Q8BGT1 (/IDA) |
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | O43155 (/HDA) |
Synaptic membrane GO:0097060
A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
|
1 | B1H234 (/IDA) |
Synaptic membrane GO:0097060
A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
|
1 | Q8BGT1 (/ISO) |
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
|
1 | Q8BGT1 (/IDA) |
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
|
1 | Q8BGT1 (/IMP) |
Integral component of postsynaptic membrane GO:0099055
The component of the postsynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q8BGT1 (/IC) |
Integral component of postsynaptic membrane GO:0099055
The component of the postsynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q8BGT1 (/IMP) |
Integral component of postsynaptic membrane GO:0099055
The component of the postsynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q8BGT1 (/ISO) |