The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Mannitol-specific EII; Chain A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 6: Fructose-specific PTS system IIA component

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity GO:0022877
Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + fructose(out) = protein histidine + fructose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
77 P69811 (/IDA) P69811 (/IDA) P69811 (/IDA) P69811 (/IDA) P69811 (/IDA) P69811 (/IDA) P69811 (/IDA) P69811 (/IDA) P69811 (/IDA) P69811 (/IDA)
(67 more)
Fructose transmembrane transporter activity GO:0005353
Enables the transfer of fructose from one side of a membrane to the other. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.
7 Q9KM70 (/ISS) Q9KM70 (/ISS) Q9KM70 (/ISS) Q9KM70 (/ISS) Q9KM70 (/ISS) Q9KM70 (/ISS) Q9KM70 (/ISS)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phosphoenolpyruvate-dependent sugar phosphotransferase system GO:0009401
The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC.
77 P69811 (/IDA) P69811 (/IDA) P69811 (/IDA) P69811 (/IDA) P69811 (/IDA) P69811 (/IDA) P69811 (/IDA) P69811 (/IDA) P69811 (/IDA) P69811 (/IDA)
(67 more)
Fructose import GO:0032445
The directed movement of the hexose monosaccharide fructose into a cell or organelle.
77 P69811 (/IDA) P69811 (/IDA) P69811 (/IDA) P69811 (/IDA) P69811 (/IDA) P69811 (/IDA) P69811 (/IDA) P69811 (/IDA) P69811 (/IDA) P69811 (/IDA)
(67 more)
Phosphoenolpyruvate-dependent sugar phosphotransferase system GO:0009401
The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC.
7 Q9KM70 (/ISS) Q9KM70 (/ISS) Q9KM70 (/ISS) Q9KM70 (/ISS) Q9KM70 (/ISS) Q9KM70 (/ISS) Q9KM70 (/ISS)
Fructose transmembrane transport GO:0015755
The directed movement of fructose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.
7 Q9KM70 (/ISS) Q9KM70 (/ISS) Q9KM70 (/ISS) Q9KM70 (/ISS) Q9KM70 (/ISS) Q9KM70 (/ISS) Q9KM70 (/ISS)
Fructose import GO:0032445
The directed movement of the hexose monosaccharide fructose into a cell or organelle.
3 Q9HY55 (/IMP) Q9HY55 (/IMP) Q9HY55 (/IMP)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extrinsic component of plasma membrane GO:0019897
The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
77 P69811 (/IDA) P69811 (/IDA) P69811 (/IDA) P69811 (/IDA) P69811 (/IDA) P69811 (/IDA) P69811 (/IDA) P69811 (/IDA) P69811 (/IDA) P69811 (/IDA)
(67 more)
CATH-Gene3D is a Global Biodata Core Resource Learn more...