The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Mannitol-specific EII; Chain A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: PTS IIA-like nitrogen regulatory protein PtsN

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
215 A0A0H3NI89 (/IPI) A0A0H3NI89 (/IPI) A0A0H3NI89 (/IPI) A0A0H3NI89 (/IPI) A0A0H3NI89 (/IPI) A0A0H3NI89 (/IPI) A0A0H3NI89 (/IPI) A0A0H3NI89 (/IPI) A0A0H3NI89 (/IPI) A0A0H3NI89 (/IPI)
(205 more)
Enzyme inhibitor activity GO:0004857
Binds to and stops, prevents or reduces the activity of an enzyme.
120 P69829 (/IMP) P69829 (/IMP) P69829 (/IMP) P69829 (/IMP) P69829 (/IMP) P69829 (/IMP) P69829 (/IMP) P69829 (/IMP) P69829 (/IMP) P69829 (/IMP)
(110 more)
Protein kinase activator activity GO:0030295
Binds to and increases the activity of a protein kinase, an enzyme which phosphorylates a protein.
120 P69829 (/IDA) P69829 (/IDA) P69829 (/IDA) P69829 (/IDA) P69829 (/IDA) P69829 (/IDA) P69829 (/IDA) P69829 (/IDA) P69829 (/IDA) P69829 (/IDA)
(110 more)
Protein-N(PI)-phosphohistidine-sugar phosphotransferase activity GO:0008982
Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sugar(out) = protein histidine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
9 Q9KP48 (/ISS) Q9KP48 (/ISS) Q9KP48 (/ISS) Q9KP48 (/ISS) Q9KP48 (/ISS) Q9KP48 (/ISS) Q9KP48 (/ISS) Q9KP48 (/ISS) Q9KP48 (/ISS)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to organonitrogen compound GO:0010243
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.
120 P69829 (/IMP) P69829 (/IMP) P69829 (/IMP) P69829 (/IMP) P69829 (/IMP) P69829 (/IMP) P69829 (/IMP) P69829 (/IMP) P69829 (/IMP) P69829 (/IMP)
(110 more)
Regulation of ion transmembrane transporter activity GO:0032412
Any process that modulates the activity of an ion transporter.
120 P69829 (/IMP) P69829 (/IMP) P69829 (/IMP) P69829 (/IMP) P69829 (/IMP) P69829 (/IMP) P69829 (/IMP) P69829 (/IMP) P69829 (/IMP) P69829 (/IMP)
(110 more)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
95 A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP)
(85 more)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
95 A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP)
(85 more)
Negative regulation of DNA binding GO:0043392
Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
95 A0A0H3NI89 (/IDA) A0A0H3NI89 (/IDA) A0A0H3NI89 (/IDA) A0A0H3NI89 (/IDA) A0A0H3NI89 (/IDA) A0A0H3NI89 (/IDA) A0A0H3NI89 (/IDA) A0A0H3NI89 (/IDA) A0A0H3NI89 (/IDA) A0A0H3NI89 (/IDA)
(85 more)
Positive regulation of growth of symbiont in host GO:0044128
Any process in which the symbiont activates, maintains or increases its size or mass within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.
95 A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP)
(85 more)
Negative regulation of growth of symbiont in host GO:0044130
Any process in which the symbiont stops, prevents or reduces its increase in size or mass within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.
95 A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP) A0A0H3NI89 (/IMP)
(85 more)
Nitrogen compound metabolic process GO:0006807
The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.
9 Q9KP48 (/ISS) Q9KP48 (/ISS) Q9KP48 (/ISS) Q9KP48 (/ISS) Q9KP48 (/ISS) Q9KP48 (/ISS) Q9KP48 (/ISS) Q9KP48 (/ISS) Q9KP48 (/ISS)
Phosphoenolpyruvate-dependent sugar phosphotransferase system GO:0009401
The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC.
9 Q9KP48 (/ISS) Q9KP48 (/ISS) Q9KP48 (/ISS) Q9KP48 (/ISS) Q9KP48 (/ISS) Q9KP48 (/ISS) Q9KP48 (/ISS) Q9KP48 (/ISS) Q9KP48 (/ISS)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
120 P69829 (/IDA) P69829 (/IDA) P69829 (/IDA) P69829 (/IDA) P69829 (/IDA) P69829 (/IDA) P69829 (/IDA) P69829 (/IDA) P69829 (/IDA) P69829 (/IDA)
(110 more)