The cell cycle process in which the distance is lengthened between poles of the mitotic spindle. Mitotic spindle elongation begins during mitotic prophase and ends during mitotic anaphase B.

The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets.

The release of duplicated mitotic spindle pole bodies (SPBs) that begins with the nucleation of microtubules from each SPB within the nucleus, leading to V-shaped spindle microtubules. Interpolar microtubules elongate from each pole forming overlapping microtubules. Capture and antiparallel sliding apart promotes initial SPB separation. Following liberation (severing of the half-bridge), SPBs diffuse through the nuclear membrane until they are opposite each other. SPB separation must take place in order for a bipolar mitotic spindle to assemble.

The release of duplicated mitotic spindle pole bodies (SPBs) that begins with the nucleation of microtubules from each SPB within the nucleus, leading to V-shaped spindle microtubules. Interpolar microtubules elongate from each pole forming overlapping microtubules. Capture and antiparallel sliding apart promotes initial SPB separation. Following liberation (severing of the half-bridge), SPBs diffuse through the nuclear membrane until they are opposite each other. SPB separation must take place in order for a bipolar mitotic spindle to assemble.

The release of duplicated mitotic spindle pole bodies (SPBs) that begins with the nucleation of microtubules from each SPB within the nucleus, leading to V-shaped spindle microtubules. Interpolar microtubules elongate from each pole forming overlapping microtubules. Capture and antiparallel sliding apart promotes initial SPB separation. Following liberation (severing of the half-bridge), SPBs diffuse through the nuclear membrane until they are opposite each other. SPB separation must take place in order for a bipolar mitotic spindle to assemble.

The removal of tubulin heterodimers from one or both ends of a microtubule.

The process in which copies of the 2-micrometer plasmid, found in fungi such as Saccharomyces, are distributed to daughter cells upon cell division.

The controlled breakdown of the spindle during a mitotic cell cycle.

The cell cycle process in which the aggregation, arrangement and bonding together of a set of components forms the spindle midzone.

The cell cycle process in which the aggregation, arrangement and bonding together of a set of components forms the spindle midzone.

The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of mitosis.

The cell cycle process in which chromosomes that are laterally attached to one or more mitotic spindle microtubules migrate towards the spindle equator via plus-end-directed movement along the microtubules. This process is part of mitotic metaphase plate congression.

Any process that stops, prevents or reduces the frequency, rate or extent of mitotic spindle elongation.

Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.

The area in the center of the spindle where the spindle microtubules from opposite poles overlap.

A multisubunit complex that is located at the centromeric region of a condensed nuclear chromosome and provides an attachment point for the spindle microtubules.

Any complex that includes a dimer of molecules from the kinesin superfamily, a group of related proteins that contain an extended region of predicted alpha-helical coiled coil in the main chain that likely produces dimerization. The native complexes of several kinesin family members have also been shown to contain additional peptides, often designated light chains as all of the noncatalytic subunits that are currently known are smaller than the chain that contains the motor unit. Kinesin complexes generally possess a force-generating enzymatic activity, or motor, which converts the free energy of the gamma phosphate bond of ATP into mechanical work.

Any multimeric complex connected to a microtubule.

Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole.

The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.

The microtubule organizing center that forms as part of the mitotic cell cycle; functionally homologous to the animal cell centrosome.

The microtubule organizing center that forms as part of the mitotic cell cycle; functionally homologous to the animal cell centrosome.

A spindle that forms as part of meiosis. Several proteins, such as budding yeast Spo21p, fission yeast Spo2 and Spo13, and C. elegans mei-1, localize specifically to the meiotic spindle and are absent from the mitotic spindle.

The area in the center of the anaphase spindle consisting of microtubules, microtubule bundling factors and kinesin motors where the spindle microtubules from opposite poles overlap in an antiparallel manner.