The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Kinesin motor domain
".
FunFam 29: Kinesin-like protein KIF17
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Motor activity GO:0003774
Catalysis of the generation of force resulting either in movement along a microfilament or microtubule, or in torque resulting in membrane scission, coupled to the hydrolysis of a nucleoside triphosphate.
|
4 | P46867 (/ISS) P46867 (/ISS) Q29DY1 (/ISS) Q29DY1 (/ISS) |
Microtubule motor activity GO:0003777
Catalysis of movement along a microtubule, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP).
|
4 | P46873 (/IDA) Q19633 (/IDA) Q965T6 (/IDA) Q99PW8 (/IDA) |
Motor activity GO:0003774
Catalysis of the generation of force resulting either in movement along a microfilament or microtubule, or in torque resulting in membrane scission, coupled to the hydrolysis of a nucleoside triphosphate.
|
2 | P46867 (/IDA) P46867 (/IDA) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q99PW8 (/IPI) |
ATP-dependent microtubule motor activity, plus-end-directed GO:0008574
Catalysis of movement along a microtubule toward the plus end, coupled to the hydrolysis of ATP.
|
1 | P46873 (/IDA) |
There are 35 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Sensory perception of smell GO:0007608
The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process.
|
3 | P46867 (/IMP) P46867 (/IMP) Q9VRK9 (/IMP) |
Anterograde axonal transport GO:0008089
The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons.
|
3 | P46867 (/IMP) P46867 (/IMP) Q9VRK9 (/IMP) |
Cell projection organization GO:0030030
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.
|
3 | A4ZYY7 (/IMP) C0L098 (/IMP) F1QV34 (/IMP) |
Establishment or maintenance of microtubule cytoskeleton polarity GO:0030951
Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures.
|
3 | P46867 (/IMP) P46867 (/IMP) Q9VRK9 (/IMP) |
Intraciliary anterograde transport GO:0035720
The directed movement of large protein complexes along microtubules from the cell body toward the tip of a cilium (also called flagellum), mediated by motor proteins.
|
3 | P46869 (/IMP) P46869 (/IMP) P46873 (/IMP) |
Photoreceptor cell outer segment organization GO:0035845
A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of the outer segment of a photoreceptor cell, a sensory cell that reacts to the presence of light. The outer segment of the photoreceptor cell contains the light-absorbing materials.
|
3 | A4ZYY7 (/IMP) C0L098 (/IMP) F1QV34 (/IMP) |
Eye photoreceptor cell development GO:0042462
Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve.
|
3 | A4ZYY7 (/IMP) C0L098 (/IMP) F1QV34 (/IMP) |
Microtubule-based movement GO:0007018
A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.
|
2 | Q19633 (/IDA) Q965T6 (/IDA) |
Microtubule-based movement GO:0007018
A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.
|
2 | P46867 (/IMP) P46867 (/IMP) |
Microtubule-based movement GO:0007018
A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.
|
2 | Q29DY1 (/ISS) Q29DY1 (/ISS) |
Anterograde axonal transport GO:0008089
The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons.
|
2 | P46867 (/IEP) P46867 (/IEP) |
Motile cilium assembly GO:0044458
The aggregation, arrangement and bonding together of a set of components to form a motile cilium.
|
2 | P46869 (/IMP) P46869 (/IMP) |
Microtubule-based process GO:0007017
Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins.
|
1 | Q99PW8 (/IDA) |
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
|
1 | Q9VRK9 (/IMP) |
Sensory perception of sound GO:0007605
The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.
|
1 | Q9VRK9 (/IMP) |
Vesicle-mediated transport GO:0016192
A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
|
1 | Q99PW8 (/IDA) |
Protein-containing complex localization GO:0031503
A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location.
|
1 | Q99PW8 (/IMP) |
Intraciliary anterograde transport GO:0035720
The directed movement of large protein complexes along microtubules from the cell body toward the tip of a cilium (also called flagellum), mediated by motor proteins.
|
1 | P46873 (/IDA) |
Intraciliary anterograde transport GO:0035720
The directed movement of large protein complexes along microtubules from the cell body toward the tip of a cilium (also called flagellum), mediated by motor proteins.
|
1 | P46873 (/IGI) |
Intraciliary transport involved in cilium assembly GO:0035735
The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly.
|
1 | Q9P2E2 (/TAS) |
Intraciliary transport GO:0042073
The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins.
|
1 | Q99PW8 (/IC) |
Intraciliary transport GO:0042073
The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins.
|
1 | P46873 (/IDA) |
Dauer entry GO:0043053
Entry into the facultative diapause of the dauer (enduring) larval stage of nematode development.
|
1 | P46873 (/IGI) |
Regulation of insulin receptor signaling pathway GO:0046626
Any process that modulates the frequency, rate or extent of insulin receptor signaling.
|
1 | P46873 (/IGI) |
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
|
1 | P46873 (/IGI) |
Positive regulation of dauer larval development GO:0061066
Any process that increases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.
|
1 | P46873 (/IMP) |
Positive regulation of canonical Wnt signaling pathway GO:0090263
Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
|
1 | Q9VRK9 (/IGI) |
Positive regulation of canonical Wnt signaling pathway GO:0090263
Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
|
1 | Q9VRK9 (/IPI) |
Anterograde dendritic transport of neurotransmitter receptor complex GO:0098971
The directed movement of a neurotransmitter receptor complex along microtubules in nerve cell dendrites towards the postsynapse.
|
1 | Q99PW8 (/IDA) |
Anterograde dendritic transport of neurotransmitter receptor complex GO:0098971
The directed movement of a neurotransmitter receptor complex along microtubules in nerve cell dendrites towards the postsynapse.
|
1 | Q99PW8 (/IMP) |
Negative regulation of non-motile cilium assembly GO:1902856
Any process that stops, prevents or reduces the frequency, rate or extent of non-motile cilium assembly.
|
1 | P46873 (/IGI) |
Positive regulation of non-motile cilium assembly GO:1902857
Any process that activates or increases the frequency, rate or extent of non-motile cilium assembly.
|
1 | P46873 (/IGI) |
Positive regulation of non-motile cilium assembly GO:1902857
Any process that activates or increases the frequency, rate or extent of non-motile cilium assembly.
|
1 | P46873 (/IMP) |
Non-motile cilium assembly GO:1905515
The aggregation, arrangement and bonding together of a set of components to form a non-motile cilium.
|
1 | P46873 (/IGI) |
Non-motile cilium assembly GO:1905515
The aggregation, arrangement and bonding together of a set of components to form a non-motile cilium.
|
1 | Q9VRK9 (/IMP) |
There are 25 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Kinesin complex GO:0005871
Any complex that includes a dimer of molecules from the kinesin superfamily, a group of related proteins that contain an extended region of predicted alpha-helical coiled coil in the main chain that likely produces dimerization. The native complexes of several kinesin family members have also been shown to contain additional peptides, often designated light chains as all of the noncatalytic subunits that are currently known are smaller than the chain that contains the motor unit. Kinesin complexes generally possess a force-generating enzymatic activity, or motor, which converts the free energy of the gamma phosphate bond of ATP into mechanical work.
|
5 | A4ZYY7 (/IDA) C0L098 (/IDA) F1QV34 (/IDA) P46873 (/IDA) Q99PW8 (/IDA) |
Ciliary basal body GO:0036064
A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.
|
5 | A4ZYY7 (/IDA) C0L098 (/IDA) F1QV34 (/IDA) P46873 (/IDA) Q99PW8 (/IDA) |
Axoneme GO:0005930
The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
|
4 | A4ZYY7 (/IDA) C0L098 (/IDA) F1QV34 (/IDA) Q99PW8 (/IDA) |
Microtubule associated complex GO:0005875
Any multimeric complex connected to a microtubule.
|
2 | P46867 (/IDA) P46867 (/IDA) |
Microtubule associated complex GO:0005875
Any multimeric complex connected to a microtubule.
|
2 | Q29DY1 (/ISS) Q29DY1 (/ISS) |
Cilium GO:0005929
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
|
2 | Q99PW8 (/IDA) Q9VRK9 (/IDA) |
Axonemal heterotrimeric kinesin-II complex GO:0030993
A kinesin complex found in eukaryotic axonemes that contains two distinct plus end-directed kinesin motor proteins and at least one accessory subunit, and that functions in the anterograde transport of molecules (cargo) from the basal body to the distal tip of the axoneme.
|
2 | Q19633 (/IPI) Q965T6 (/IPI) |
Motile cilium GO:0031514
A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell.
|
2 | P46869 (/IDA) P46869 (/IDA) |
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
|
2 | P46869 (/IDA) P46869 (/IDA) |
Early endosome GO:0005769
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
|
1 | Q9VRK9 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9P2E2 (/TAS) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q9VRK9 (/IDA) |
Adherens junction GO:0005912
A cell junction at which anchoring proteins (cadherins or integrins) extend through the plasma membrane and are attached to actin filaments.
|
1 | Q9VRK9 (/IDA) |
Cilium GO:0005929
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
|
1 | Q9P2E2 (/ISS) |
Cilium GO:0005929
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
|
1 | Q9P2E2 (/TAS) |
Microtubule cytoskeleton GO:0015630
The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.
|
1 | Q99PW8 (/IDA) |
Cell junction GO:0030054
A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.
|
1 | Q9VRK9 (/IMP) |
Intraciliary transport particle B GO:0030992
The larger subcomplex of the intraciliary transport particle; characterized complexes have molecular weights around 550 kDa.
|
1 | Q99PW8 (/IDA) |
Photoreceptor connecting cilium GO:0032391
The portion of the photoreceptor cell cilium linking the photoreceptor inner and outer segments. It's considered to be equivalent to the ciliary transition zone.
|
1 | Q99PW8 (/IDA) |
Ciliary basal body GO:0036064
A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.
|
1 | Q99PW8 (/ISO) |
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
|
1 | P46873 (/IDA) |
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
|
1 | P46873 (/IDA) |
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
1 | P46873 (/IDA) |
Non-motile cilium GO:0097730
A cilium which may have a variable array of axonemal microtubules but does not contain molecular motors.
|
1 | P46873 (/IDA) |
Periciliary membrane compartment GO:1990075
A plasma membrane region adjacent to the base of eukaryotic cilia and flagella that is enriched in endocytosis-associated proteins and vesicles and that appears to regulate ciliary membrane homeostasis.
|
1 | Q99PW8 (/IDA) |