The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Histone deacetylase domain
".
FunFam 25: Histone deacetylase HOS1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Histone deacetylase activity GO:0004407
Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes.
|
3 | Q12214 (/ISA) Q12214 (/ISA) Q12214 (/ISA) |
|
Protein deacetylase activity GO:0033558
Catalysis of the hydrolysis of an acetyl group or groups from a protein substrate.
|
3 | Q12214 (/IDA) Q12214 (/IDA) Q12214 (/IDA) |
|
Protein deacetylase activity GO:0033558
Catalysis of the hydrolysis of an acetyl group or groups from a protein substrate.
|
3 | Q12214 (/IMP) Q12214 (/IMP) Q12214 (/IMP) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Peptidyl-lysine deacetylation GO:0034983
The removal of an acetyl group from an acetylated lysine residue in a peptide or protein.
|
3 | Q12214 (/IDA) Q12214 (/IDA) Q12214 (/IDA) |
|
Peptidyl-lysine deacetylation GO:0034983
The removal of an acetyl group from an acetylated lysine residue in a peptide or protein.
|
3 | Q12214 (/IMP) Q12214 (/IMP) Q12214 (/IMP) |
|
Peptidyl-lysine deacetylation GO:0034983
The removal of an acetyl group from an acetylated lysine residue in a peptide or protein.
|
3 | Q12214 (/IPI) Q12214 (/IPI) Q12214 (/IPI) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
3 | Q12214 (/IMP) Q12214 (/IMP) Q12214 (/IMP) |
|
Transfer RNA gene-mediated silencing GO:0061587
The chromatin silencing that results in the inhibition of RNA polymerase II-transcribed genes located in the vicinity of tRNA genes.
|
3 | Q12214 (/IMP) Q12214 (/IMP) Q12214 (/IMP) |
|
Histone H4 deacetylation GO:0070933
The modification of histone H4 by the removal of one or more acetyl groups.
|
3 | Q12214 (/IMP) Q12214 (/IMP) Q12214 (/IMP) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Histone deacetylase complex GO:0000118
A protein complex that possesses histone deacetylase activity.
|
3 | Q12214 (/IPI) Q12214 (/IPI) Q12214 (/IPI) |