The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Histone deacetylase domain
".
FunFam 21: histone deacetylase 6 isoform X1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Histone deacetylase activity GO:0004407
Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes.
|
7 | M9NEH6 (/IDA) M9NGF7 (/IDA) M9PJN5 (/IDA) Q86NK9 (/IDA) Q8IR37 (/IDA) Q8IR38 (/IDA) Q9XYX1 (/IDA) |
|
Histone deacetylase activity GO:0004407
Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes.
|
7 | M9NEH6 (/IMP) M9NGF7 (/IMP) M9PJN5 (/IMP) Q86NK9 (/IMP) Q8IR37 (/IMP) Q8IR38 (/IMP) Q9XYX1 (/IMP) |
|
Deacetylase activity GO:0019213
Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule.
|
7 | M9NEH6 (/IMP) M9NGF7 (/IMP) M9PJN5 (/IMP) Q86NK9 (/IMP) Q8IR37 (/IMP) Q8IR38 (/IMP) Q9XYX1 (/IMP) |
There are 4 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
7 | M9NEH6 (/IDA) M9NGF7 (/IDA) M9PJN5 (/IDA) Q86NK9 (/IDA) Q8IR37 (/IDA) Q8IR38 (/IDA) Q9XYX1 (/IDA) |
|
Neurotransmitter secretion GO:0007269
The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission.
|
7 | M9NEH6 (/IMP) M9NGF7 (/IMP) M9PJN5 (/IMP) Q86NK9 (/IMP) Q8IR37 (/IMP) Q8IR38 (/IMP) Q9XYX1 (/IMP) |
|
Histone deacetylation GO:0016575
The modification of histones by removal of acetyl groups.
|
7 | M9NEH6 (/IDA) M9NGF7 (/IDA) M9PJN5 (/IDA) Q86NK9 (/IDA) Q8IR37 (/IDA) Q8IR38 (/IDA) Q9XYX1 (/IDA) |
|
Histone deacetylation GO:0016575
The modification of histones by removal of acetyl groups.
|
7 | M9NEH6 (/IMP) M9NGF7 (/IMP) M9PJN5 (/IMP) Q86NK9 (/IMP) Q8IR37 (/IMP) Q8IR38 (/IMP) Q9XYX1 (/IMP) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
7 | M9NEH6 (/IDA) M9NGF7 (/IDA) M9PJN5 (/IDA) Q86NK9 (/IDA) Q8IR37 (/IDA) Q8IR38 (/IDA) Q9XYX1 (/IDA) |