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CATH Superfamily 3.40.800.20

Histone deacetylase domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Histone deacetylase domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 10: Histone deacetylase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Histone deacetylase activity GO:0004407
Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes.
 17 Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA)
(7 more)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Histone deacetylation GO:0016575
The modification of histones by removal of acetyl groups.
 17 Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA)
(7 more)
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
 17 Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA)
(7 more)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
 17 Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA) Q7K6A1 (/IDA)
(7 more)