The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1Cystathionine gamma-synthaseCystathionine gamma-lyaseCystathionine gamma-lyaseCystathionine beta-lyaseSC:2Cysteine desulfurase IscSPhosphoserine aminotransferaseOrnithine aminotransferasealanine aminotransferase 2Alanine aminotransferase AlaCPyridoxal phosphate-dependent aminotransferaseGlutamate decarboxylaseHistidinol-phosphate aminotransferaseTryptophanaseCysteine desulfuraseAspartate aminotransferaseProbable 4-aminobutyrate aminotransferaseN-succinyldiaminopimelate aminotransferase DapCAdenosylmethionine-8-amino-7-oxononanoate aminotransferaseLPS biosynthesis proteinCysteine desulfurase CsdASelenocysteine lyaseIscS-like cysteine desulfuraseL-threonine aldolaseBifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferaseAminotransferase, DegT/DnrJ/EryC1/StrS familyPyridoxal phosphate-dependent aminotransferaseTyrosine phenol-lyaseL-tryptophan--pyruvate aminotransferase 18-amino-7-oxononanoate synthaseSerine hydroxymethyltransferaseKynureninaseSerine hydroxymethyltransferaseProbable cysteine desulfuraseAspartate aminotransferasePossible aminotransferaseHistidinol-phosphate aminotransferaseSerine-pyruvate aminotransferase (AgxT)Threonine aldolaseL-allo-threonine aldolaseCAI-1 autoinducer synthaseAlanine aminotransferase 2UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminaseKynurenine--oxoglutarate transaminase 1UPF0425 pyridoxal phosphate-dependent protein MJ0158Pyridoxamine--pyruvate transaminase8-amino-3,8-dideoxy-alpha-D-manno-octulosonate transaminaseSC:3O-phosphoseryl-tRNA(Sec) selenium transferaseSerine hydroxymethyltransferaseSerine hydroxymethyltransferaseAcetylornithine aminotransferaseGlycine dehydrogenase (decarboxylating), mitochondrial5-aminolevulinate synthase, mitochondrialglycine dehydrogenase (Decarboxylating), mitochondrialLysine decarboxylase, inducibleCystathionine gamma-synthase homolog4-aminobutyrate aminotransferaseAdenosylmethionine-8-amino-7-oxononanoate aminotransferase, probableAspartate aminotransferaseGlutamate decarboxylase like 1Glutamate decarboxylasesphingosine-1-phosphate lyase 1Glutamate-1-semialdehyde 2,1-aminomutaseTranscriptional regulator, GntR familyKynurenine--oxoglutarate transaminase 3Histidine decarboxylaseAspartate aminotransferaseSerine--pyruvate aminotransferase, mitochondrialL-seryl-tRNA(Sec) selenium transferase4-aminobutyrate aminotransferase, mitochondrialLow-specificity L-threonine aldolaseKynureninaseAspartate aminotransferaseProbable glycine dehydrogenase (decarboxylating) subunit 2O-succinylhomoserine sulfhydrylasepyridoxal-dependent decarboxylase domain-containing protein 1 isoform X2dTDP-4-amino-4,6-dideoxygalactose transaminaseUDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferaseAdenosylmethionine-8-amino-7-oxononanoate aminotransferaseValine--pyruvate aminotransferaseserine palmitoyltransferase 2 isoform X1tyrosine aminotransferaseserine palmitoyltransferase 1 isoform X1Serine hydroxymethyltransferase1-aminocyclopropane-1-carboxylate synthase 3Aspartate aminotransferaseAminotransferase, class ISerine--glyoxylate aminotransferaseAlanine--glyoxylate aminotransferase 2, mitochondrialSelA-like pyridoxal phosphate-dependent enzymePhosphoserine aminotransferaseethanolamine-phosphate phospho-lyase isoform X1Serine palmitoyl CoA transferase subunit LcbASerine hydroxymethyltransferaseCystathionine gamma-synthaseprobable low-specificity L-threonine aldolase 1Aspartate aminotransferaseSerine hydroxymethyltransferaseAspartate aminotransferaseAminotransferase, class I/classIIPutative aminotransferaseSerine decarboxylase 1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrialPutative cystathionine beta-lyaseAromatic amino acid aminotransferaseMaltose regulon modulator MalYSpore coat polysaccharide biosynthesis protein spsCAminotransferase, putativePhosphoserine aminotransferaseCystathionine gamma-lyaseKynurenine--oxoglutarate transaminase 1Diaminobutyrate--2-oxoglutarate aminotransferaseProbable cystathionine gamma-synthaseMolybdenum cofactor sulfuraseSerine hydroxymethyltransferaseGlutamic-oxaloacetic transaminase 1 like 1LL-diaminopimelate aminotransferase, chloroplasticPutative acetylornithine aminotransferase1-aminocyclopropane-1-carboxylate synthase homolog (inactive)L-allo-threonine aldolaseAlanine aminotransferase, putativeCysteine desulfurase, mitochondrialCysteine desulfurase IscSAminotransferaseAminotransferaseCystathionine gamma-synthaseProbable glycine dehydrogenase (decarboxylating) subunit 1Transcriptional regulator, GntR familyGntR family transcriptional regulatorPyridoxal phosphate (PLP)-dependent transferases superfamily proteinAcetylornithine aminotransferaseAcetylornithine aminotransferaseMolybdenum cofactor sulfurasePutative cystathionine beta-lyaseBifunctional dethiobiotin synthetase/adenosylmethionine-8-amino-7-oxononanoate aminotransferaseDegT/DnrJ/EryC1/StrS family aminotransferaseAcetylornithine aminotransferaseProbable L-tyrosine/L-aspartate decarboxylaseAminotransferaseAromatic amino acid aminotransferase C56E4.03Serine hydroxymethyltransferase, mitochondrialAlanine aminotransferase 28-amino-7-oxononanoate synthaseHISTIDINE BIOSYNTHESIS 6BSerine C-palmitoyltransferase, putativeDihydrodipicolinate reductaseSerine hydroxymethyltransferase, putativeTranscriptional regulator PtsJCystathionine beta-lyaseLong chain base biosynthesis protein 2aAcetylornithine aminotransferaseGlutamate decarboxylasePutative ornithine aminotransferase RocD2DegT/DnrJ/EryC1/StrS aminotransferase family proteinPhosphoserine aminotransferaseAminotransferase DegTAspartate aminotransferaseAspartate aminotransferaseArginine decarboxylaseHistidinol-phosphate aminotransferaseCystathionine beta-lyaseAdenosylmethionine-8-amino-7-oxononanoate aminotransferaseSerine-pyruvate aminotransferase, putativeSerine palmitoyltransferase componentAminotransferase, class VRelated to GLY1-L-threonine aldolase, low-specificUncharacterized protein, isoform AAspartate aminotransferaseGlycine dehydrogenase (decarboxylating)Uncharacterized protein R102.4Class III pyridoxal phosphate-dependent aminotransferaseUnplaced genomic scaffold supercont1.20, whole genome shotgun sequenceDegT/DnrJ/EryC1/StrS aminotransferase family proteinPhosphoserine transaminase, putativeCystathionine gamma-lyase, putativeProtein CBG17192Cysteine desulfurasePutative serine palmitoyltransferasePutative ornithine aminotransferase RocD1L-lysine 6-aminotransferase4-aminobutyrate aminotransferaseBnaA05g34080D proteinPyridoxal phosphate-dependent aminotransferasePossible 8-amino-7-oxononanoate synthase bioF2Probable hercynylcysteine sulfoxide lyaseYLL058W-like proteinNucleotide sugar transaminaseUnplaced genomic scaffold supercont1.16, whole genome shotgun sequenceAminotransferase, class I/II domain proteinAminotransferaseBiogenic Amine Synthesis relatedcystathionine gamma-lyase4-aminobutyrate aminotransferase2-aminoethylphosphonate--pyruvate transaminasePutative threonine aldolaseOrnithine aminotransferaseAminotransferase, class IIIBiotin FUnplaced genomic scaffold supercont1.10, whole genome shotgun sequenceGlycine dehydrogenase (decarboxylating)7-keto-8-aminopelargonate synthetasePerosamine synthaseDegT/DnrJ/EryC1/StrS aminotransferase family proteinPredicted proteinARO9p Aromatic aminotransferase IIAromatic amino acid aminotransferase IGlycine dehydrogenase (decarboxylating)Dubious cystathionine gamma-lyaseGlycine dehydrogenase [decarboxylating], mitochondrialAspartate aminotransferaseProbable aminotransferaseserine palmitoyltransferase 2Putative aspartate aminotransferaseUncharacterized proteinDegT/DnrJ/EryC1/StrS aminotransferase family proteinDecarboxylase, group IIPLP-dependent transferaseAminotransferaseSerine hydroxymethyltransferase mitochondrial-likeGamma-aminobutyrate transaminase POP2 mitochondrialPutative serine--glyoxylate aminotransferaseProbable aminotransferaseAspartate aminotransferaseCysteine desulfuraseAminotransferaseAminotransferase PigEKynureninasePLP-dependent transferaseUncharacterized proteinGntR family transcriptional regulatorProbable glycine dehydrogenase (decarboxylating) subunit 2Glycine dehydrogenase [decarboxylating], mitochondrialAlanine aminotransferase 2Predicted proteinAspartate aminotransferaseAminotransferaseNeamine transaminase NeoNAminotransferaseAdenosylmethionine-8-amino-7-oxononanoate transaminaseAminotransferase class V-fold PLP-dependent enzymeAdenosylmethionine-8-amino-7-oxononanoate aminotransferaseAminotransferaseMethionine S-methyltransferaseMolybdenum cofactor sulfuraseCystathionine beta lyaseMolybdenum cofactor sulfuraseGlutamate decarboxylase isoform 67Perosamine synthetaseCytochrome D ubiquinol oxidase subunit IL-cysteine desulfhydraseKynureninaseArginine decarboxylaseAminotransferase, class IAdenosylmethionine-8-amino-7-oxononanoate aminotransferaseAminotransferase class-IIIAminotransferase, class VSoluble hydrogenase, small subunitUncharacterized proteinNucleotide sugar transaminaseAspartate aminotransferaseDegT/DnrJ/EryC1/StrS family aminotransferaseNTD biosynthesis operon protein NtdADegT/DnrJ/EryC1/StrS family aminotransferaseCystathionine gamma-synthaseAminotransferaseAromatic aminotransferase ISS1Ornithine aminotransferaseKynurenine aminotransferase, putativeSerine hydroxymethyltransferase, mitochondrialProbable glycine dehydrogenase (decarboxylating) subunit 2L-seryl-tRNA(Sec) selenium transferaseGlutamic-oxaloacetic transaminase 1, solubleCapreomycidine synthaseAminotransferase, class V familyProbable aminotransferase gliIProbable 8-amino-7-oxononanoate synthase (Eurofung)Aminotransferase, putativeTaurine--pyruvate aminotransferaseBifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial40S ribosomal protein S4-3Glutamate decarboxylase 1Uncharacterized proteinAcetylornithine aminotransferase, mitochondrialGamma-aminobutyrate transaminase POP2 mitochondrialPredicted proteinO-acetyl-L-homoserine sulfhydrylaseLow specificity L-threonine aldolasedTDP-4-dehydro-6-deoxy-D-glucose 4-aminotransferaseProbable acetylornithine aminotransferaseUncharacterized proteinUncharacterized proteinAromatic amino acid aminotransferase DDB_G0272014Pyridoxal phosphate-dependent transferaseAromatic amino acid aminotransferase, putativeTranscriptional regulator, GntR familyPyridoxal dependent decarboxylase domain containing 1Uncharacterized proteinAspartate aminotransferaseHercynylcysteine sulfoxide lyaseProbable glycine dehydrogenase (decarboxylating) subunit 2Glycine cleavage system P-proteinL-seryl-tRNA(Sec) selenium transferasePyridoxal phosphate-dependent transferase4-aminobutyrate aminotransferaseUncharacterized aminotransferase C27F1.05cSi:ch211-180m24.3Aspartate aminotransferase, mitochondrial(S)-3,5-dihydroxyphenylglycine transaminaseUncharacterized proteinAminotransferase, class IIIAminotransferase class I and IIHistidinol-phosphate aminotransferaseSimilar to aspartate aminotransferaseAminotransferase class-IIIPyridoxal phosphate-dependent aminotransferaseUncharacterized proteinAspartate aminotransferaseMitochondrial aspartate aminotransferaseAdenosylmethionine-8-amino-7-oxononanoate aminotransferase family proteinKynureninaseUncharacterized proteinProbable L-aspartate decarboxylaseSerine hydroxymethyltransferaseAspartate aminotransferaseTranscriptional regulatory proteinPredicted proteinAlanine aminotransferase, putativeUncharacterized proteinSphingosine Phosphate LyaseDethiobiotin synthaseGlutamate decarboxylase 1bAromatic-amino-acid transaminase, hypothetical (Eurofung)ATP-binding cassette sub-family A member 3-like ProteinSaframycin Mx1 synthetase BAromatic-amino-acid transaminase, hypothetical (Eurofung)Serine-pyruvate aminotransferaseUncharacterized proteinPredicted proteinPredicted proteinSerine--glyoxylate aminotransferaseCystathionine gamma-synthase3-amino-5-hydroxybenzoic acid synthaseGlutamine--scyllo-inositol transaminaseCystathionine gamma-lyaseLow-specificity L-threonine aldolasePerosamine synthetaseUncharacterized proteinCys/Met metabolism pyridoxal-phosphate-dependent proteinSpore coat polysaccharide biosynthesis proteinSpsCDegT/DnrJ/EryC1/StrS aminotransferaseUncharacterized proteinPutative low-specificity L-threonine aldolase 1DegT/DnrJ/EryC1/StrS aminotransferaseLipopolysaccharide biosynthesis protein RfbHUncharacterized proteinCystathionine synthase/lyase (Cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)C4 aminotransferase for PseB product PseCPyridoxal phosphate (PLP)-dependent transferases superfamily proteinUncharacterized proteinCystathionine Beta LyaseMethionine gamma-lyase, putativePredicted proteinAspartate aminotransferasePyridoxal phosphate-dependent aminotransferaseAminotransferaseAminotransferase class I/II-fold pyridoxal phosphate-dependent enzymeAspartate aminotransferaseSerine--pyruvate aminotransferasePLP-dependent transferaseOrnithine aminotransferaseUncharacterized proteinPLP-dependent aminotransferase family proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinOs01g0711400 proteinPhosphoserineaminotransferase, putative1KynureninaseUncharacterized proteinUncharacterized proteinProbable glycine dehydrogenase (decarboxylating) subunit 2Glycine dehydrogenase (Decarboxylating)Uncharacterized proteinAspartate aminotransferase, putativeUncharacterized proteinAminotransferase (Class 5)Serine--pyruvate aminotransferase2'-deamino-2'-hydroxyneamine transaminaseAspartate aminotransferaseCobalamin biosynthetic protein CobCUncharacterized proteinRE16411pGlutamic-oxaloacetic transaminase 1-like 1Sphingosine-1-phosphate lyase 1Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinOrnithine aminotransferaseUncharacterized proteinUncharacterized aminotransferase C1771.03cPredicted proteinUncharacterized aminotransferase C1039.07cUncharacterized proteinAminotransferase, class IAminotransferase, class VUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinAlanine aminotransferase 2 mitochondrialPredicted proteinOs09g0278300 proteinBifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrialPredicted proteinUncharacterized proteinSerine--pyruvate aminotransferasePredicted proteinSerine hydroxymethyltransferase, mitochondrialPredicted proteinUncharacterized proteinSerine--pyruvate aminotransferaseGlutamic--pyruvic transaminaseAspartate aminotransferaseUncharacterized proteinPredicted proteinAlanine aminotransferaseUncharacterized proteinUncharacterized proteinUncharacterized proteinSerine--pyruvate aminotransferaseGlutamine--scyllo-inositol transaminaseUncharacterized proteinPredicted proteinTranscriptional regulator (DegT/DnrJ/Eryc1 family)Aminoadipate aminotransferaseUncharacterized proteinPredicted proteinPerosamine synthetase-related proteinProtein CBR-GOT-1.3Uncharacterized proteinCystathionase, putativeUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinAlanine aminotransferase, putativeUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinDegT/DnrJ/EryC1/StrS aminotransferase family proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinLipopolysaccharide biosynthesis protein RfbHUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinSerine hydroxymethyltransferase 4Uncharacterized proteinPutative serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit TON2Alanine aminotransferase 2 mitochondrialUncharacterized proteinOrnithine aminotransferaseUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinPredicted proteinAlanine aminotransferase 2 mitochondrialUncharacterized proteinUncharacterized proteinAminotransferase tdiDkynurenine/alpha-aminoadipate aminotransferase, mitochondrial-like isoform X4Aromatic amino acid aminotransferase DDB_G0287711-like ProteinUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinPredicted proteinKynureninaseOrnithine aminotransferaseKynurenine aminotransferase, putativeAminotransferase, conjecturalUncharacterized proteinUncharacterized proteinUncharacterized proteinPutative diaminobutyrate-pyruvate aminotransferasePredicted proteinUncharacterized proteinAminotransferase, conjecturalUncharacterized proteinUncharacterized proteinSerine--pyruvate aminotransferaseUncharacterized proteinUncharacterized proteinSerine hydroxymethyltransferasePutative diaminobutyrate-pyruvate aminotransferaseUncharacterized proteinSelenocysteine lyaseUncharacterized proteinUncharacterized proteinSerine--pyruvate aminotransferaseOrnithine aminotransferaseUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinSerine--pyruvate aminotransferaseUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized protein
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FunFam 170: 4-aminobutyrate aminotransferase

GO Diversity

Unique GO annotations
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EC Diversity

Unique EC annotations
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Species Diversity

Unique species annotations
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Statistics

Members
CATH Domains: 0
Sequences: 10
Annotations
Unique GO: 2
Unique EC: 0
Unique Species: 10
Representative
Rep ID: Q885E5/49-308
Inherited Annotations: 0
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