The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Peptidase C12, ubiquitin carboxyl-terminal hydrolase
".
FunFam 6: Ubiquitin carboxyl-terminal hydrolase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Ubiquitin binding GO:0043130
Interacting selectively and non-covalently with ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation.
|
6 | Q8IKM8 (/IDA) Q8IKM8 (/IDA) Q8IKM8 (/IDA) Q8IKM8 (/IDA) Q8IKM8 (/IDA) Q8IKM8 (/IDA) |
|
Thiol-dependent ubiquitin-specific protease activity GO:0004843
Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein.
|
2 | P35122 (/IDA) P35122 (/IDA) |
There are 4 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
|
8 | P35122 (/IDA) P35122 (/IDA) Q8IKM8 (/IDA) Q8IKM8 (/IDA) Q8IKM8 (/IDA) Q8IKM8 (/IDA) Q8IKM8 (/IDA) Q8IKM8 (/IDA) |
|
Protein deneddylation GO:0000338
The removal of a ubiquitin-like protein of the NEDD8 type from a protein.
|
6 | Q8IKM8 (/IDA) Q8IKM8 (/IDA) Q8IKM8 (/IDA) Q8IKM8 (/IDA) Q8IKM8 (/IDA) Q8IKM8 (/IDA) |
|
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
|
6 | Q8IKM8 (/ISS) Q8IKM8 (/ISS) Q8IKM8 (/ISS) Q8IKM8 (/ISS) Q8IKM8 (/ISS) Q8IKM8 (/ISS) |
|
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
|
2 | Q387M6 (/ISM) Q387M6 (/ISM) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Ubiquitin ligase complex GO:0000151
A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex.
|
6 | Q8IKM8 (/IDA) Q8IKM8 (/IDA) Q8IKM8 (/IDA) Q8IKM8 (/IDA) Q8IKM8 (/IDA) Q8IKM8 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q387M6 (/IDA) Q387M6 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q387M6 (/ISA) Q387M6 (/ISA) |
|
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
|
2 | Q387M6 (/IDA) Q387M6 (/IDA) |
|
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
|
2 | Q387M6 (/IDA) Q387M6 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q4QA77 (/ISO) |
|
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
|
1 | Q4QA77 (/ISO) |
|
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
|
1 | Q4QA77 (/ISO) |