The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 26: Protein/nucleic acid deglycase HchA

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
14 P31658 (/IPI) P31658 (/IPI) P31658 (/IPI) P31658 (/IPI) P31658 (/IPI) P31658 (/IPI) P31658 (/IPI) P31658 (/IPI) P31658 (/IPI) P31658 (/IPI)
(4 more)
Glyoxalase III activity GO:0019172
Catalysis of the reaction: methylglyoxal + H2O = D-lactate.
14 P31658 (/IDA) P31658 (/IDA) P31658 (/IDA) P31658 (/IDA) P31658 (/IDA) P31658 (/IDA) P31658 (/IDA) P31658 (/IDA) P31658 (/IDA) P31658 (/IDA)
(4 more)
Protein deglycase activity GO:0036524
Catalysis of the removal of a sugar or dicarbonyl from a lysine residue of a glycated protein.
14 P31658 (/IDA) P31658 (/IDA) P31658 (/IDA) P31658 (/IDA) P31658 (/IDA) P31658 (/IDA) P31658 (/IDA) P31658 (/IDA) P31658 (/IDA) P31658 (/IDA)
(4 more)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA repair GO:0006281
The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
14 P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP)
(4 more)
Protein deglycosylation GO:0006517
The removal of sugar residues from a glycosylated protein.
14 P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP)
(4 more)
Response to acidic pH GO:0010447
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.
14 P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP)
(4 more)
Methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione GO:0019243
The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into D-lactate via the intermediate S-lactoyl-glutathione. Glutathione is used in the first step of the pathway and then regenerated in the second step.
14 P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP)
(4 more)
Protein repair GO:0030091
The process of restoring a protein to its original state after damage by such things as oxidation or spontaneous decomposition of residues.
14 P31658 (/IDA) P31658 (/IDA) P31658 (/IDA) P31658 (/IDA) P31658 (/IDA) P31658 (/IDA) P31658 (/IDA) P31658 (/IDA) P31658 (/IDA) P31658 (/IDA)
(4 more)
RNA repair GO:0042245
Any process that results in the repair of damaged RNA.
14 P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP)
(4 more)
Response to methylglyoxal GO:0051595
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal.
14 P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP) P31658 (/IMP)
(4 more)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
14 P31658 (/HDA) P31658 (/HDA) P31658 (/HDA) P31658 (/HDA) P31658 (/HDA) P31658 (/HDA) P31658 (/HDA) P31658 (/HDA) P31658 (/HDA) P31658 (/HDA)
(4 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
14 P31658 (/IDA) P31658 (/IDA) P31658 (/IDA) P31658 (/IDA) P31658 (/IDA) P31658 (/IDA) P31658 (/IDA) P31658 (/IDA) P31658 (/IDA) P31658 (/IDA)
(4 more)