The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
HUPs
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9: Cysteine--tRNA ligase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Aminoacyl-tRNA ligase activity GO:0004812
Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of diphosphate and AMP.
7 P21888 (/IDA) P21888 (/IDA) P21888 (/IDA) P21888 (/IDA) P21888 (/IDA) P21888 (/IDA) P21888 (/IDA)
Cysteine-tRNA ligase activity GO:0004817
Catalysis of the reaction: ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys).
7 P21888 (/IDA) P21888 (/IDA) P21888 (/IDA) P21888 (/IDA) P21888 (/IDA) P21888 (/IDA) P21888 (/IDA)
Cysteine-tRNA ligase activity GO:0004817
Catalysis of the reaction: ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys).
7 Q9KQZ9 (/ISS) Q9KQZ9 (/ISS) Q9KQZ9 (/ISS) Q9KQZ9 (/ISS) Q9KQZ9 (/ISS) Q9KQZ9 (/ISS) Q9KQZ9 (/ISS)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
7 P21888 (/IPI) P21888 (/IPI) P21888 (/IPI) P21888 (/IPI) P21888 (/IPI) P21888 (/IPI) P21888 (/IPI)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
7 P21888 (/IDA) P21888 (/IDA) P21888 (/IDA) P21888 (/IDA) P21888 (/IDA) P21888 (/IDA) P21888 (/IDA)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
7 P21888 (/IPI) P21888 (/IPI) P21888 (/IPI) P21888 (/IPI) P21888 (/IPI) P21888 (/IPI) P21888 (/IPI)
Ligase activity GO:0016874
Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
7 P21888 (/IDA) P21888 (/IDA) P21888 (/IDA) P21888 (/IDA) P21888 (/IDA) P21888 (/IDA) P21888 (/IDA)
Metal ion binding GO:0046872
Interacting selectively and non-covalently with any metal ion.
7 P21888 (/IPI) P21888 (/IPI) P21888 (/IPI) P21888 (/IPI) P21888 (/IPI) P21888 (/IPI) P21888 (/IPI)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cysteinyl-tRNA aminoacylation GO:0006423
The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. A cysteinyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a cysteine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
7 P21888 (/IDA) P21888 (/IDA) P21888 (/IDA) P21888 (/IDA) P21888 (/IDA) P21888 (/IDA) P21888 (/IDA)
Cysteinyl-tRNA aminoacylation GO:0006423
The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. A cysteinyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a cysteine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
7 Q9KQZ9 (/ISS) Q9KQZ9 (/ISS) Q9KQZ9 (/ISS) Q9KQZ9 (/ISS) Q9KQZ9 (/ISS) Q9KQZ9 (/ISS) Q9KQZ9 (/ISS)
Regulation of translation GO:0006417
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
2 Q0IZQ2 (/ISS) Q0IZQ2 (/ISS)
Polar nucleus fusion GO:0010197
The merging of the polar nuclei, the two nuclei contained within the same cell that are created from the mitotic division of the megaspore during angiosperm reproduction. Polar nuclear fusion takes place in the ovule, forming in the fusion nucleus and giving rise to the endosperm when fertilized.
2 F4IPY2 (/IMP) F4IPY2 (/IMP)
Cristae formation GO:0042407
The assembly of cristae, the inwards folds of the inner mitochondrial membrane.
2 F4IPY2 (/IMP) F4IPY2 (/IMP)
Regulation of programmed cell death GO:0043067
Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
2 F4IPY2 (/IMP) F4IPY2 (/IMP)
Regulation of translation GO:0006417
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
1 A0A1D6LAG9 (/IMP)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
1 B3LFA4 (/IEP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
8 B3LFA4 (/IDA) P21888 (/IDA) P21888 (/IDA) P21888 (/IDA) P21888 (/IDA) P21888 (/IDA) P21888 (/IDA) P21888 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
3 A0A1D6LAG9 (/IDA) F4IPY2 (/IDA) F4IPY2 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 F4IPY2 (/IDA) F4IPY2 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
2 Q0IZQ2 (/ISS) Q0IZQ2 (/ISS)
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
2 F4IPY2 (/IDA) F4IPY2 (/IDA)
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