The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
HUPs
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6: bifunctional 3'-phosphoadenosine 5'-phosphosulfate...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 17 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Sulfate adenylyltransferase (ATP) activity GO:0004781
Catalysis of the reaction: ATP + sulfate = diphosphate + adenylylsulfate.
18 O43252 (/ISS) O43252 (/ISS) O43252 (/ISS) O54820 (/ISS) O88428 (/ISS) O95340 (/ISS) O95340 (/ISS) O95340 (/ISS) O95340 (/ISS) O95340 (/ISS)
(8 more)
Nucleotidyltransferase activity GO:0016779
Catalysis of the transfer of a nucleotidyl group to a reactant.
17 O43252 (/ISS) O43252 (/ISS) O43252 (/ISS) O54820 (/ISS) O88428 (/ISS) O95340 (/ISS) O95340 (/ISS) O95340 (/ISS) O95340 (/ISS) O95340 (/ISS)
(7 more)
Sulfate adenylyltransferase (ATP) activity GO:0004781
Catalysis of the reaction: ATP + sulfate = diphosphate + adenylylsulfate.
7 O43252 (/IDA) O43252 (/IDA) O43252 (/IDA) O88428 (/IDA) Q22501 (/IDA) Q60967 (/IDA) Q9UIR2 (/IDA)
Adenylylsulfate kinase activity GO:0004020
Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate.
6 O43252 (/IDA) O43252 (/IDA) O43252 (/IDA) O88428 (/IDA) Q22501 (/IDA) Q60967 (/IDA)
Sulfate adenylyltransferase (ATP) activity GO:0004781
Catalysis of the reaction: ATP + sulfate = diphosphate + adenylylsulfate.
5 O23324 (/IMP) O23324 (/IMP) Q43870 (/IMP) Q43870 (/IMP) Q9S7D8 (/IMP)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
3 O43252 (/IPI) O43252 (/IPI) O43252 (/IPI)
Sulfate adenylyltransferase (ATP) activity GO:0004781
Catalysis of the reaction: ATP + sulfate = diphosphate + adenylylsulfate.
2 Q9LIK9 (/TAS) Q9LIK9 (/TAS)
Adenylylsulfate kinase activity GO:0004020
Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate.
1 Q27128 (/IGI)
Adenylylsulfate kinase activity GO:0004020
Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate.
1 Q60967 (/ISO)
Adenylylsulfate kinase activity GO:0004020
Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate.
1 O54820 (/ISS)
Sulfate adenylyltransferase (ATP) activity GO:0004781
Catalysis of the reaction: ATP + sulfate = diphosphate + adenylylsulfate.
1 Q27128 (/IGI)
Sulfate adenylyltransferase (ATP) activity GO:0004781
Catalysis of the reaction: ATP + sulfate = diphosphate + adenylylsulfate.
1 Q60967 (/ISO)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 Q27128 (/NAS)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 Q9UIR2 (/TAS)
Transferase activity GO:0016740
Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
1 Q9UIR2 (/TAS)
Nucleotidyltransferase activity GO:0016779
Catalysis of the transfer of a nucleotidyl group to a reactant.
1 Q9UIR2 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 Q60967 (/ISO)

There are 17 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Skeletal system development GO:0001501
The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).
9 O43252 (/TAS) O43252 (/TAS) O43252 (/TAS) O95340 (/TAS) O95340 (/TAS) O95340 (/TAS) O95340 (/TAS) O95340 (/TAS) Q9UIR2 (/TAS)
3'-phosphoadenosine 5'-phosphosulfate biosynthetic process GO:0050428
The chemical reactions and pathways resulting in the formation of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.
8 O43252 (/TAS) O43252 (/TAS) O43252 (/TAS) O95340 (/TAS) O95340 (/TAS) O95340 (/TAS) O95340 (/TAS) O95340 (/TAS)
Sulfate assimilation GO:0000103
The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.
5 O23324 (/TAS) O23324 (/TAS) Q43870 (/TAS) Q43870 (/TAS) Q9S7D8 (/TAS)
3'-phosphoadenosine 5'-phosphosulfate biosynthetic process GO:0050428
The chemical reactions and pathways resulting in the formation of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.
5 O43252 (/IDA) O43252 (/IDA) O43252 (/IDA) Q22501 (/IDA) Q60967 (/IDA)
Sulfate assimilation GO:0000103
The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.
4 O43252 (/IDA) O43252 (/IDA) O43252 (/IDA) O88428 (/IDA)
Cellular response to sulfate starvation GO:0009970
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfate.
4 O23324 (/IEP) O23324 (/IEP) Q43870 (/IEP) Q43870 (/IEP)
Sulfate assimilation GO:0000103
The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.
2 O54820 (/ISS) Q60967 (/ISS)
Selenium compound metabolic process GO:0001887
The chemical reactions and pathways involving compounds that contain selenium, such as selenocysteine.
2 Q9LIK9 (/IMP) Q9LIK9 (/IMP)
Response to cytokinin GO:0009735
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus.
2 Q9LIK9 (/IDA) Q9LIK9 (/IDA)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
2 Q9LIK9 (/IEP) Q9LIK9 (/IEP)
Protein trimerization GO:0070206
The formation of a protein trimer, a macromolecular structure consisting of three noncovalently associated identical or nonidentical subunits.
2 O23324 (/IDA) O23324 (/IDA)
Sulfate assimilation GO:0000103
The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.
1 Q27128 (/IGI)
Sulfate assimilation GO:0000103
The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.
1 Q60967 (/ISO)
Blood coagulation GO:0007596
The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.
1 O88428 (/IMP)
3'-phosphoadenosine 5'-phosphosulfate biosynthetic process GO:0050428
The chemical reactions and pathways resulting in the formation of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.
1 Q60967 (/ISO)
3'-phosphoadenosine 5'-phosphosulfate biosynthetic process GO:0050428
The chemical reactions and pathways resulting in the formation of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.
1 O54820 (/ISS)
Bone development GO:0060348
The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components.
1 O88428 (/IMP)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
10 B2RYI8 (/TAS) B5DFH4 (/TAS) O43252 (/TAS) O43252 (/TAS) O43252 (/TAS) O95340 (/TAS) O95340 (/TAS) O95340 (/TAS) O95340 (/TAS) O95340 (/TAS)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
5 Q43870 (/IDA) Q43870 (/IDA) Q9LIK9 (/IDA) Q9LIK9 (/IDA) Q9S7D8 (/IDA)
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
5 Q43870 (/IDA) Q43870 (/IDA) Q9LIK9 (/IDA) Q9LIK9 (/IDA) Q9S7D8 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
4 Q7KUT8 (/HDA) Q8IQV1 (/HDA) Q961A8 (/HDA) Q9VW48 (/HDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
4 O23324 (/NAS) O23324 (/NAS) Q43870 (/NAS) Q43870 (/NAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q43870 (/IDA) Q43870 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q9LIK9 (/IDA) Q9LIK9 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q22501 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q9S7D8 (/IDA)
Sulfate adenylyltransferase complex (ATP) GO:0009336
An enzyme complex that catalyzes the formation adenylylsulfate from sulfate and ATP.
1 Q60967 (/IC)
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