View in Gene3D

CATH Superfamily 3.40.50.620

HUPs

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
HUPs
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 153: Phosphoadenosine phosphosulfate reductase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phosphoadenylyl-sulfate reductase (thioredoxin). [EC: 1.8.4.8]
Adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenylyl sulfate + thioredoxin.
  • Specific for PAPS.
  • The enzyme from Escherichia coli will use thioredoxins from other species.
  • Formerly EC 1.8.99.4.
 51 A0A0C7CX40 A0A0C7CX40 A0A0C7CX40 A0A0C7CX40 A0A0C7CX40 A0A0C7CX40 A0A0C7CX40 A0A157WSG9 A0A157WSG9 A0A157WSG9
(41 more...)
Adenylyl-sulfate reductase (glutathione). [EC: 1.8.4.9]
AMP + sulfite + glutathione disulfide = adenylyl sulfate + 2 glutathione.
  • Differs from EC 1.8.99.2, in using glutathione as the reductant.
  • Glutathione can be replaced by gamma-glutamylcysteine or dithiothreitol, but not by thioredoxin, glutaredoxin or mercaptoethanol.
  • The enzyme from Arabidopsis thaliana contains a glutaredoxin-like domain.
  • Also found in other photosynthetic eukaryotes, e.g., the Madagascar periwinkle, Catharanthus roseus and the hollow green seaweed, Enteromorpha intestinalis.
 3 P92979 P92980 P92981
CATH-Gene3D is a Global Biodata Core Resource Learn more...