The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 89: Eukaryotic initiation factor 4A-II

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 25 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
155 F4JEL4 (/IPI) P10081 (/IPI) P10081 (/IPI) P10081 (/IPI) P10081 (/IPI) P10081 (/IPI) P10081 (/IPI) P10081 (/IPI) P10081 (/IPI) P41376 (/IPI)
(145 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
86 P60842 (/HDA) P60842 (/HDA) P60842 (/HDA) P60842 (/HDA) P60842 (/HDA) P60842 (/HDA) P60842 (/HDA) P60842 (/HDA) P60842 (/HDA) P60842 (/HDA)
(76 more)
Helicase activity GO:0004386
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.
86 P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS)
(76 more)
RNA cap binding GO:0000339
Interacting selectively and non-covalently with a 7-methylguanosine (m7G) group or derivative located at the 5' end of an RNA molecule.
49 P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS)
(39 more)
Double-stranded RNA binding GO:0003725
Interacting selectively and non-covalently with double-stranded RNA.
49 P60842 (/IDA) P60842 (/IDA) P60842 (/IDA) P60842 (/IDA) P60842 (/IDA) P60842 (/IDA) P60842 (/IDA) P60842 (/IDA) P60842 (/IDA) P60842 (/IDA)
(39 more)
Double-stranded RNA binding GO:0003725
Interacting selectively and non-covalently with double-stranded RNA.
49 P60843 (/ISO) P60843 (/ISO) P60843 (/ISO) P60843 (/ISO) P60843 (/ISO) P60843 (/ISO) P60843 (/ISO) P60843 (/ISO) P60843 (/ISO) P60843 (/ISO)
(39 more)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
49 P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS)
(39 more)
Translation factor activity, RNA binding GO:0008135
Functions during translation by interacting selectively and non-covalently with RNA during polypeptide synthesis at the ribosome.
49 P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS)
(39 more)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
49 Q14240 (/IDA) Q14240 (/IDA) Q14240 (/IDA) Q14240 (/IDA) Q14240 (/IDA) Q14240 (/IDA) Q14240 (/IDA) Q14240 (/IDA) Q14240 (/IDA) Q14240 (/IDA)
(39 more)
Translation initiation factor activity GO:0003743
Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
37 Q14240 (/TAS) Q14240 (/TAS) Q14240 (/TAS) Q14240 (/TAS) Q14240 (/TAS) Q14240 (/TAS) Q14240 (/TAS) Q14240 (/TAS) Q14240 (/TAS) Q14240 (/TAS)
(27 more)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
37 P10630 (/ISO) P10630 (/ISO) P10630 (/ISO) P10630 (/ISO) P10630 (/ISO) P10630 (/ISO) P10630 (/ISO) P10630 (/ISO) P10630 (/ISO) P10630 (/ISO)
(27 more)
Translation initiation factor activity GO:0003743
Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
35 P87206 (/ISS) P87206 (/ISS) P87206 (/ISS) P87206 (/ISS) Q02748 (/ISS) Q02748 (/ISS) Q8IFN9 (/ISS) Q8IFN9 (/ISS) Q8IFN9 (/ISS) Q8IFN9 (/ISS)
(25 more)
RNA helicase activity GO:0003724
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix.
19 Q02748 (/ISS) Q02748 (/ISS) Q8IFN9 (/ISS) Q8IFN9 (/ISS) Q8IFN9 (/ISS) Q8IFN9 (/ISS) Q8IFN9 (/ISS) Q8IFN9 (/ISS) Q8IFN9 (/ISS) Q8IFN9 (/ISS)
(9 more)
RNA cap binding GO:0000339
Interacting selectively and non-covalently with a 7-methylguanosine (m7G) group or derivative located at the 5' end of an RNA molecule.
12 Q8IKF0 (/ISS) Q8IKF0 (/ISS) Q8IKF0 (/ISS) Q8IKF0 (/ISS) Q8IKF0 (/ISS) Q8IKF0 (/ISS) Q8IKF0 (/ISS) Q8IKF0 (/ISS) Q8IKF0 (/ISS) Q8IKF0 (/ISS)
(2 more)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
12 Q8IKF0 (/ISS) Q8IKF0 (/ISS) Q8IKF0 (/ISS) Q8IKF0 (/ISS) Q8IKF0 (/ISS) Q8IKF0 (/ISS) Q8IKF0 (/ISS) Q8IKF0 (/ISS) Q8IKF0 (/ISS) Q8IKF0 (/ISS)
(2 more)
Helicase activity GO:0004386
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.
12 Q8IKF0 (/IDA) Q8IKF0 (/IDA) Q8IKF0 (/IDA) Q8IKF0 (/IDA) Q8IKF0 (/IDA) Q8IKF0 (/IDA) Q8IKF0 (/IDA) Q8IKF0 (/IDA) Q8IKF0 (/IDA) Q8IKF0 (/IDA)
(2 more)
3'-5' DNA/RNA helicase activity GO:0033679
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of a DNA/RNA duplex in the direction 3' to 5'.
12 Q8IKF0 (/IDA) Q8IKF0 (/IDA) Q8IKF0 (/IDA) Q8IKF0 (/IDA) Q8IKF0 (/IDA) Q8IKF0 (/IDA) Q8IKF0 (/IDA) Q8IKF0 (/IDA) Q8IKF0 (/IDA) Q8IKF0 (/IDA)
(2 more)
Translation initiation factor activity GO:0003743
Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
9 P10081 (/IMP) P10081 (/IMP) P10081 (/IMP) P10081 (/IMP) P10081 (/IMP) P10081 (/IMP) P10081 (/IMP) P10081 (/IMP) P47943 (/IMP)
RNA helicase activity GO:0003724
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix.
8 P10081 (/IDA) P10081 (/IDA) P10081 (/IDA) P10081 (/IDA) P10081 (/IDA) P10081 (/IDA) P10081 (/IDA) P10081 (/IDA)
RNA helicase activity GO:0003724
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix.
8 P10081 (/IMP) P10081 (/IMP) P10081 (/IMP) P10081 (/IMP) P10081 (/IMP) P10081 (/IMP) P10081 (/IMP) P10081 (/IMP)
Translation initiation factor activity GO:0003743
Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
8 P10081 (/IDA) P10081 (/IDA) P10081 (/IDA) P10081 (/IDA) P10081 (/IDA) P10081 (/IDA) P10081 (/IDA) P10081 (/IDA)
RNA-dependent ATPase activity GO:0008186
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of RNA, and it drives another reaction.
8 P10081 (/IDA) P10081 (/IDA) P10081 (/IDA) P10081 (/IDA) P10081 (/IDA) P10081 (/IDA) P10081 (/IDA) P10081 (/IDA)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
2 P41377 (/IDA) P41377 (/IDA)
SMAD binding GO:0046332
Interacting selectively and non-covalently with a SMAD signaling protein.
2 Q02748 (/IPI) Q02748 (/IPI)
RNA helicase activity GO:0003724
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix.
1 P47943 (/ISO)

There are 24 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Translational initiation GO:0006413
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
86 P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS)
(76 more)
Regulation of translational initiation GO:0006446
Any process that modulates the frequency, rate or extent of translational initiation.
37 Q14240 (/TAS) Q14240 (/TAS) Q14240 (/TAS) Q14240 (/TAS) Q14240 (/TAS) Q14240 (/TAS) Q14240 (/TAS) Q14240 (/TAS) Q14240 (/TAS) Q14240 (/TAS)
(27 more)
Negative regulation of RNA-directed 5'-3' RNA polymerase activity GO:1900260
Any process that stops, prevents or reduces the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity.
37 Q14240 (/IDA) Q14240 (/IDA) Q14240 (/IDA) Q14240 (/IDA) Q14240 (/IDA) Q14240 (/IDA) Q14240 (/IDA) Q14240 (/IDA) Q14240 (/IDA) Q14240 (/IDA)
(27 more)
Negative regulation of RNA-directed 5'-3' RNA polymerase activity GO:1900260
Any process that stops, prevents or reduces the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity.
37 P10630 (/ISO) P10630 (/ISO) P10630 (/ISO) P10630 (/ISO) P10630 (/ISO) P10630 (/ISO) P10630 (/ISO) P10630 (/ISO) P10630 (/ISO) P10630 (/ISO)
(27 more)
Cellular response to leukemia inhibitory factor GO:1990830
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus.
37 P10630 (/IEP) P10630 (/IEP) P10630 (/IEP) P10630 (/IEP) P10630 (/IEP) P10630 (/IEP) P10630 (/IEP) P10630 (/IEP) P10630 (/IEP) P10630 (/IEP)
(27 more)
Regulation of translational initiation GO:0006446
Any process that modulates the frequency, rate or extent of translational initiation.
29 Q8IFN9 (/ISS) Q8IFN9 (/ISS) Q8IFN9 (/ISS) Q8IFN9 (/ISS) Q8IFN9 (/ISS) Q8IFN9 (/ISS) Q8IFN9 (/ISS) Q8IFN9 (/ISS) Q8IFN9 (/ISS) Q8IFN9 (/ISS)
(19 more)
Translational initiation GO:0006413
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
8 P10081 (/IDA) P10081 (/IDA) P10081 (/IDA) P10081 (/IDA) P10081 (/IDA) P10081 (/IDA) P10081 (/IDA) P10081 (/IDA)
Translational initiation GO:0006413
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
8 P10081 (/IMP) P10081 (/IMP) P10081 (/IMP) P10081 (/IMP) P10081 (/IMP) P10081 (/IMP) P10081 (/IMP) P10081 (/IMP)
Translational initiation GO:0006413
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
7 F4JEL4 (/ISS) P87206 (/ISS) P87206 (/ISS) P87206 (/ISS) P87206 (/ISS) Q02748 (/ISS) Q02748 (/ISS)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
3 F4JEL4 (/IEP) P41377 (/IEP) P41377 (/IEP)
Mitotic cell cycle GO:0000278
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
2 Q02748 (/HMP) Q02748 (/HMP)
Regulation of alternative mRNA splicing, via spliceosome GO:0000381
Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
2 Q02748 (/HMP) Q02748 (/HMP)
Regulation of alternative mRNA splicing, via spliceosome GO:0000381
Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
2 Q02748 (/IMP) Q02748 (/IMP)
Pole cell formation GO:0007279
Formation of a small group of cells (pole cells) at the posterior pole of the insect blastula. They are the first cells to cellularize after the arrival of nuclei at the end of the syncytial blastula stage and are the precursors to the insect germ cells.
2 Q02748 (/IGI) Q02748 (/IGI)
Negative regulation of BMP signaling pathway GO:0030514
Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
2 Q02748 (/IDA) Q02748 (/IDA)
Negative regulation of BMP signaling pathway GO:0030514
Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
2 Q02748 (/IMP) Q02748 (/IMP)
Germ-line stem cell population maintenance GO:0030718
Any process by which an organism or tissue maintains a population of germ-line stem cells.
2 Q02748 (/IMP) Q02748 (/IMP)
Positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436
Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
2 Q02748 (/IDA) Q02748 (/IDA)
Female germ-line stem cell asymmetric division GO:0048132
The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes.
2 Q02748 (/IGI) Q02748 (/IGI)
Female germ-line stem cell asymmetric division GO:0048132
The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes.
2 Q02748 (/IMP) Q02748 (/IMP)
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
2 Q02748 (/IGI) Q02748 (/IGI)
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
2 Q02748 (/IMP) Q02748 (/IMP)
Cytoplasmic translational initiation GO:0002183
The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
1 P47943 (/IMP)
Unidimensional cell growth GO:0009826
The process in which a cell irreversibly increases in size in one
1 I1GWP1 (/IMP)

There are 30 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
86 P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS)
(76 more)
Eukaryotic translation initiation factor 4F complex GO:0016281
The eukaryotic translation initiation factor 4F complex is composed of eIF4E, eIF4A and eIF4G; it is involved in the recognition of the mRNA cap, ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of the mRNA to the ribosome.
86 P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS) P60842 (/TAS)
(76 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
68 P60842 (/IDA) P60842 (/IDA) P60842 (/IDA) P60842 (/IDA) P60842 (/IDA) P60842 (/IDA) P60842 (/IDA) P60842 (/IDA) P60842 (/IDA) P60842 (/IDA)
(58 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
49 P60843 (/ISO) P60843 (/ISO) P60843 (/ISO) P60843 (/ISO) P60843 (/ISO) P60843 (/ISO) P60843 (/ISO) P60843 (/ISO) P60843 (/ISO) P60843 (/ISO)
(39 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
49 P60842 (/HDA) P60842 (/HDA) P60842 (/HDA) P60842 (/HDA) P60842 (/HDA) P60842 (/HDA) P60842 (/HDA) P60842 (/HDA) P60842 (/HDA) P60842 (/HDA)
(39 more)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
49 P60842 (/HDA) P60842 (/HDA) P60842 (/HDA) P60842 (/HDA) P60842 (/HDA) P60842 (/HDA) P60842 (/HDA) P60842 (/HDA) P60842 (/HDA) P60842 (/HDA)
(39 more)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
37 Q14240 (/IDA) Q14240 (/IDA) Q14240 (/IDA) Q14240 (/IDA) Q14240 (/IDA) Q14240 (/IDA) Q14240 (/IDA) Q14240 (/IDA) Q14240 (/IDA) Q14240 (/IDA)
(27 more)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
37 P10630 (/ISO) P10630 (/ISO) P10630 (/ISO) P10630 (/ISO) P10630 (/ISO) P10630 (/ISO) P10630 (/ISO) P10630 (/ISO) P10630 (/ISO) P10630 (/ISO)
(27 more)
Eukaryotic translation initiation factor 4F complex GO:0016281
The eukaryotic translation initiation factor 4F complex is composed of eIF4E, eIF4A and eIF4G; it is involved in the recognition of the mRNA cap, ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of the mRNA to the ribosome.
31 Q02748 (/ISS) Q02748 (/ISS) Q8IFN9 (/ISS) Q8IFN9 (/ISS) Q8IFN9 (/ISS) Q8IFN9 (/ISS) Q8IFN9 (/ISS) Q8IFN9 (/ISS) Q8IFN9 (/ISS) Q8IFN9 (/ISS)
(21 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
9 F4JEL4 (/IDA) P41377 (/IDA) P41377 (/IDA) Q02748 (/IDA) Q02748 (/IDA) Q6FQQ6 (/IDA) Q6FQQ6 (/IDA) Q9CAI7 (/IDA) Q9CAI7 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
8 P10081 (/HDA) P10081 (/HDA) P10081 (/HDA) P10081 (/HDA) P10081 (/HDA) P10081 (/HDA) P10081 (/HDA) P10081 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
8 P10081 (/HDA) P10081 (/HDA) P10081 (/HDA) P10081 (/HDA) P10081 (/HDA) P10081 (/HDA) P10081 (/HDA) P10081 (/HDA)
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
8 P10081 (/IDA) P10081 (/IDA) P10081 (/IDA) P10081 (/IDA) P10081 (/IDA) P10081 (/IDA) P10081 (/IDA) P10081 (/IDA)
Eukaryotic translation initiation factor 4F complex GO:0016281
The eukaryotic translation initiation factor 4F complex is composed of eIF4E, eIF4A and eIF4G; it is involved in the recognition of the mRNA cap, ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of the mRNA to the ribosome.
8 P10081 (/IMP) P10081 (/IMP) P10081 (/IMP) P10081 (/IMP) P10081 (/IMP) P10081 (/IMP) P10081 (/IMP) P10081 (/IMP)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
7 Q6Z2Z4 (/IDA) Q6Z2Z4 (/IDA) Q6Z2Z4 (/IDA) Q6Z2Z4 (/IDA) Q6Z2Z4 (/IDA) Q6Z2Z4 (/IDA) Q6Z2Z4 (/IDA)
Vacuolar membrane GO:0005774
The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.
4 P41377 (/IDA) P41377 (/IDA) Q9CAI7 (/IDA) Q9CAI7 (/IDA)
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
3 F4JEL4 (/IDA) P41377 (/IDA) P41377 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q02748 (/HDA) Q02748 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q02748 (/IC) Q02748 (/IC)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q02748 (/ISS) Q02748 (/ISS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 P41377 (/IDA) P41377 (/IDA)
Plant-type cell wall GO:0009505
A more or less rigid stucture lying outside the cell membrane of a cell and composed of cellulose and pectin and other organic and inorganic substances.
2 Q9CAI7 (/IDA) Q9CAI7 (/IDA)
P granule GO:0043186
A small cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.
2 Q02748 (/IDA) Q02748 (/IDA)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
1 F4JEL4 (/IDA)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
1 F4JEL4 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P47943 (/HDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 F4JEL4 (/IDA)
Eukaryotic translation initiation factor 4F complex GO:0016281
The eukaryotic translation initiation factor 4F complex is composed of eIF4E, eIF4A and eIF4G; it is involved in the recognition of the mRNA cap, ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of the mRNA to the ribosome.
1 P47943 (/ISO)
Phagocytic vesicle GO:0045335
A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
1 P90529 (/HDA)
Apoplast GO:0048046
The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it.
1 F4JEL4 (/IDA)
CATH-Gene3D is a Global Biodata Core Resource Learn more...