The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"P-loop containing nucleotide triphosphate hydrolases
".
FunFam 79: probable ATP-dependent RNA helicase DDX17
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 54 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
39 |
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
(29 more) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
37 |
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
(27 more) |
|
Promoter-specific chromatin binding GO:1990841
Interacting selectively and non-covalently with a section of chromatin that is associated with gene promoter sequences of DNA.
|
33 |
A5A6J2 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
(23 more) |
|
RNA helicase activity GO:0003724
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix.
|
30 |
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
(20 more) |
|
RNA helicase activity GO:0003724
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix.
|
30 |
P17844 (/NAS)
P17844 (/NAS)
P17844 (/NAS)
P17844 (/NAS)
P17844 (/NAS)
P17844 (/NAS)
P17844 (/NAS)
P17844 (/NAS)
P17844 (/NAS)
P17844 (/NAS)
(20 more) |
|
MRNA 3'-UTR binding GO:0003730
Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule.
|
30 |
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
(20 more) |
|
MH2 domain binding GO:0035500
Interacting selectively and non-covalently with the MH2 (MAD homology 2) domain of a protein. The MH2 domain is found at the carboxy-terminus of MAD related proteins such as Smads. The MH2 domain mediates interaction with a wide variety of proteins and provides specificity and selectivity to Smad function and also is critical for mediating interactions in Smad oligomers.
|
30 |
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
(20 more) |
|
Pre-mRNA binding GO:0036002
Interacting selectively and non-covalently with pre-messenger RNA (pre-mRNA), an intermediate molecule between DNA and protein that may contain introns and, at least in part, encodes one or more proteins. Introns are removed from pre-mRNA to form a mRNA molecule.
|
30 |
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
(20 more) |
|
Ribonucleoprotein complex binding GO:0043021
Interacting selectively and non-covalently with any complex of RNA and protein.
|
30 |
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
(20 more) |
|
SMAD binding GO:0046332
Interacting selectively and non-covalently with a SMAD signaling protein.
|
30 |
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
(20 more) |
|
Androgen receptor binding GO:0050681
Interacting selectively and non-covalently with an androgen receptor.
|
30 |
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
(20 more) |
|
R-SMAD binding GO:0070412
Interacting selectively and non-covalently with a receptor-regulated SMAD signaling protein.
|
30 |
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
P17844 (/IPI)
(20 more) |
|
Primary miRNA binding GO:0070878
Interacting selectively and non-covalently with a primary microRNA (pri-miRNA) transcript, an RNA molecule that is processed into a short hairpin-shaped structure called a pre-miRNA and finally into a functional miRNA. Both double-stranded and single-stranded regions of a pri-miRNA are required for binding.
|
30 |
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
(20 more) |
|
Helicase activity GO:0004386
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.
|
13 |
Q7K4L8 (/ISS)
Q8IL13 (/ISS)
Q8IL13 (/ISS)
Q8IL13 (/ISS)
Q8IL13 (/ISS)
Q8IL13 (/ISS)
Q8IL13 (/ISS)
Q8IL13 (/ISS)
Q8IL13 (/ISS)
Q8IL13 (/ISS)
(3 more) |
|
Nucleic acid binding GO:0003676
Interacting selectively and non-covalently with any nucleic acid.
|
11 |
Q8IL13 (/ISS)
Q8IL13 (/ISS)
Q8IL13 (/ISS)
Q8IL13 (/ISS)
Q8IL13 (/ISS)
Q8IL13 (/ISS)
Q8IL13 (/ISS)
Q8IL13 (/ISS)
Q8IL13 (/ISS)
Q8IL13 (/ISS)
(1 more) |
|
RNA helicase activity GO:0003724
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix.
|
9 | A5A6J2 (/ISS) P24782 (/ISS) Q4R6M5 (/ISS) Q5R4I9 (/ISS) Q61656 (/ISS) Q7KU78 (/ISS) Q8MZI3 (/ISS) Q9VXW2 (/ISS) Q9W3M7 (/ISS) |
|
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
|
4 | Q580H2 (/IDA) Q580H2 (/IDA) Q8W4R3 (/IDA) Q8W4R3 (/IDA) |
|
MRNA 3'-UTR binding GO:0003730
Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule.
|
4 | A5A6J2 (/ISS) Q4R6M5 (/ISS) Q5R4I9 (/ISS) Q61656 (/ISS) |
|
Ribonucleoprotein complex binding GO:0043021
Interacting selectively and non-covalently with any complex of RNA and protein.
|
4 | A5A6J2 (/ISS) Q4R6M5 (/ISS) Q5R4I9 (/ISS) Q61656 (/ISS) |
|
Androgen receptor binding GO:0050681
Interacting selectively and non-covalently with an androgen receptor.
|
4 | A5A6J2 (/ISS) Q4R6M5 (/ISS) Q5R4I9 (/ISS) Q61656 (/ISS) |
|
Helicase activity GO:0004386
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.
|
3 | Q26696 (/ISM) Q580H2 (/ISM) Q580H2 (/ISM) |
|
Calmodulin binding GO:0005516
Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.
|
3 | Q6AYI1 (/IDA) Q6AYI1 (/IDA) Q6AYI1 (/IDA) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
3 | Q26696 (/ISM) Q580H2 (/ISM) Q580H2 (/ISM) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
3 | Q6AYI1 (/IDA) Q6AYI1 (/IDA) Q6AYI1 (/IDA) |
|
Calcium-dependent protein binding GO:0048306
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of calcium.
|
3 | Q6AYI1 (/IDA) Q6AYI1 (/IDA) Q6AYI1 (/IDA) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
2 | Q92841 (/TAS) Q9NXZ2 (/TAS) |
|
RNA helicase activity GO:0003724
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix.
|
2 | Q61656 (/ISO) Q9P7C7 (/ISO) |
|
RNA helicase activity GO:0003724
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix.
|
2 | Q92841 (/TAS) Q9NXZ2 (/TAS) |
|
Transcription coregulator activity GO:0003712
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to either activate or repress the transcription of specific genes. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class modulates interactions of DNA-binding transcription factor with other transcription coregulators.
|
1 | Q61656 (/IDA) |
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
1 | Q92841 (/IDA) |
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
1 | Q501J6 (/ISO) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | Q61656 (/IDA) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | Q54CE0 (/ISS) |
|
RNA helicase activity GO:0003724
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix.
|
1 | P24783 (/IDA) |
|
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
|
1 | P19109 (/ISS) |
|
MRNA 3'-UTR binding GO:0003730
Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule.
|
1 | Q61656 (/ISO) |
|
Calmodulin binding GO:0005516
Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.
|
1 | Q61656 (/ISO) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
1 | P24782 (/ISS) |
|
RNA-dependent ATPase activity GO:0008186
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of RNA, and it drives another reaction.
|
1 | P24783 (/IDA) |
|
RNA-dependent ATPase activity GO:0008186
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of RNA, and it drives another reaction.
|
1 | P24783 (/IMP) |
|
RNA-dependent ATPase activity GO:0008186
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of RNA, and it drives another reaction.
|
1 | Q92841 (/TAS) |
|
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
|
1 | Q9P7C7 (/IDA) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
1 | Q61656 (/ISO) |
|
MH2 domain binding GO:0035500
Interacting selectively and non-covalently with the MH2 (MAD homology 2) domain of a protein. The MH2 domain is found at the carboxy-terminus of MAD related proteins such as Smads. The MH2 domain mediates interaction with a wide variety of proteins and provides specificity and selectivity to Smad function and also is critical for mediating interactions in Smad oligomers.
|
1 | Q61656 (/ISO) |
|
Pre-mRNA binding GO:0036002
Interacting selectively and non-covalently with pre-messenger RNA (pre-mRNA), an intermediate molecule between DNA and protein that may contain introns and, at least in part, encodes one or more proteins. Introns are removed from pre-mRNA to form a mRNA molecule.
|
1 | Q61656 (/ISO) |
|
Ribonucleoprotein complex binding GO:0043021
Interacting selectively and non-covalently with any complex of RNA and protein.
|
1 | Q61656 (/ISO) |
|
SMAD binding GO:0046332
Interacting selectively and non-covalently with a SMAD signaling protein.
|
1 | Q61656 (/ISO) |
|
Calcium-dependent protein binding GO:0048306
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of calcium.
|
1 | Q61656 (/ISO) |
|
Androgen receptor binding GO:0050681
Interacting selectively and non-covalently with an androgen receptor.
|
1 | Q61656 (/ISO) |
|
R-SMAD binding GO:0070412
Interacting selectively and non-covalently with a receptor-regulated SMAD signaling protein.
|
1 | Q61656 (/ISO) |
|
Primary miRNA binding GO:0070878
Interacting selectively and non-covalently with a primary microRNA (pri-miRNA) transcript, an RNA molecule that is processed into a short hairpin-shaped structure called a pre-miRNA and finally into a functional miRNA. Both double-stranded and single-stranded regions of a pri-miRNA are required for binding.
|
1 | Q61656 (/ISO) |
|
U1 snRNP binding GO:1990446
Interacting selectively and non-covalently with any part of a U1 small nuclear ribonucleoprotein particle.
|
1 | Q9P7C7 (/IDA) |
|
U2 snRNP binding GO:1990447
Interacting selectively and non-covalently with any part of a U2 small nuclear ribonucleoprotein particle.
|
1 | Q9P7C7 (/IDA) |
|
Promoter-specific chromatin binding GO:1990841
Interacting selectively and non-covalently with a section of chromatin that is associated with gene promoter sequences of DNA.
|
1 | Q61656 (/IDA) |
There are 93 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
|
36 |
P17844 (/TAS)
P17844 (/TAS)
P17844 (/TAS)
P17844 (/TAS)
P17844 (/TAS)
P17844 (/TAS)
P17844 (/TAS)
P17844 (/TAS)
P17844 (/TAS)
P17844 (/TAS)
(26 more) |
|
Myoblast differentiation GO:0045445
The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers.
|
34 |
A5A6J2 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
(24 more) |
|
Regulation of skeletal muscle cell differentiation GO:2001014
Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation.
|
34 |
A5A6J2 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
(24 more) |
|
Alternative mRNA splicing, via spliceosome GO:0000380
The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition.
|
33 |
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
(23 more) |
|
Regulation of osteoblast differentiation GO:0045667
Any process that modulates the frequency, rate or extent of osteoblast differentiation.
|
33 |
A5A6J2 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
(23 more) |
|
Pri-miRNA transcription by RNA polymerase II GO:0061614
The cellular synthesis of primary microRNA (pri-miRNA) transcripts from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. pri-miRNA transcripts are subsequently processed to produce the ~22nt miRNAs that function in gene regulation.
|
33 |
A5A6J2 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
P17844 (/ISS)
(23 more) |
|
Regulation of alternative mRNA splicing, via spliceosome GO:0000381
Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
|
32 |
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
(22 more) |
|
Regulation of alternative mRNA splicing, via spliceosome GO:0000381
Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
|
31 |
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
(21 more) |
|
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
|
31 |
P17844 (/IC)
P17844 (/IC)
P17844 (/IC)
P17844 (/IC)
P17844 (/IC)
P17844 (/IC)
P17844 (/IC)
P17844 (/IC)
P17844 (/IC)
P17844 (/IC)
(21 more) |
|
Epithelial to mesenchymal transition GO:0001837
A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
|
31 |
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
(21 more) |
|
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
31 |
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
(21 more) |
|
Intracellular estrogen receptor signaling pathway GO:0030520
Any series of molecular signals generated as a consequence of an intracellular estrogen receptor binding to one of its physiological ligands. The pathway begins with receptor-ligand binding, and ends with regulation of a downstream cellular process (e.g. transcription).
|
31 |
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
(21 more) |
|
Androgen receptor signaling pathway GO:0030521
Any series of molecular signals generated as a consequence of an androgen binding to its receptor.
|
31 |
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
(21 more) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
30 |
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
(20 more) |
|
Nuclear-transcribed mRNA catabolic process GO:0000956
The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells.
|
30 |
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
(20 more) |
|
MRNA transcription GO:0009299
The cellular synthesis of messenger RNA (mRNA) from a DNA template.
|
30 |
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
(20 more) |
|
BMP signaling pathway GO:0030509
A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
30 |
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
(20 more) |
|
Positive regulation of DNA damage response, signal transduction by p53 class mediator GO:0043517
Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
|
30 |
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
(20 more) |
|
Regulation of androgen receptor signaling pathway GO:0060765
Any process that modulates the rate, frequency, or extent of the androgen receptor signaling pathway.
|
30 |
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
(20 more) |
|
Intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332
A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, and ends when the execution phase of apoptosis is triggered.
|
30 |
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
(20 more) |
|
Positive regulation of production of miRNAs involved in gene silencing by miRNA GO:1903800
Any process that activates or increases the frequency, rate or extent of production of miRNAs involved in gene silencing by miRNA.
|
30 |
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
P17844 (/IMP)
(20 more) |
|
Alternative mRNA splicing, via spliceosome GO:0000380
The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition.
|
5 | A5A6J2 (/ISS) Q4R6M5 (/ISS) Q501J6 (/ISS) Q5R4I9 (/ISS) Q61656 (/ISS) |
|
Epithelial to mesenchymal transition GO:0001837
A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
|
5 | A5A6J2 (/ISS) Q4R6M5 (/ISS) Q501J6 (/ISS) Q5R4I9 (/ISS) Q61656 (/ISS) |
|
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
5 | A5A6J2 (/ISS) Q4R6M5 (/ISS) Q501J6 (/ISS) Q5R4I9 (/ISS) Q61656 (/ISS) |
|
Intracellular estrogen receptor signaling pathway GO:0030520
Any series of molecular signals generated as a consequence of an intracellular estrogen receptor binding to one of its physiological ligands. The pathway begins with receptor-ligand binding, and ends with regulation of a downstream cellular process (e.g. transcription).
|
5 | A5A6J2 (/ISS) Q4R6M5 (/ISS) Q501J6 (/ISS) Q5R4I9 (/ISS) Q61656 (/ISS) |
|
Androgen receptor signaling pathway GO:0030521
Any series of molecular signals generated as a consequence of an androgen binding to its receptor.
|
5 | A5A6J2 (/ISS) Q4R6M5 (/ISS) Q501J6 (/ISS) Q5R4I9 (/ISS) Q61656 (/ISS) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
4 | A5A6J2 (/ISS) Q4R6M5 (/ISS) Q5R4I9 (/ISS) Q61656 (/ISS) |
|
Regulation of alternative mRNA splicing, via spliceosome GO:0000381
Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
|
4 | A5A6J2 (/ISS) Q4R6M5 (/ISS) Q5R4I9 (/ISS) Q61656 (/ISS) |
|
Nuclear-transcribed mRNA catabolic process GO:0000956
The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells.
|
4 | A5A6J2 (/ISS) Q4R6M5 (/ISS) Q5R4I9 (/ISS) Q61656 (/ISS) |
|
Positive regulation of DNA damage response, signal transduction by p53 class mediator GO:0043517
Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
|
4 | A5A6J2 (/ISS) Q4R6M5 (/ISS) Q5R4I9 (/ISS) Q61656 (/ISS) |
|
Regulation of androgen receptor signaling pathway GO:0060765
Any process that modulates the rate, frequency, or extent of the androgen receptor signaling pathway.
|
4 | A5A6J2 (/ISS) Q4R6M5 (/ISS) Q5R4I9 (/ISS) Q61656 (/ISS) |
|
Intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332
A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, and ends when the execution phase of apoptosis is triggered.
|
4 | A5A6J2 (/ISS) Q4R6M5 (/ISS) Q5R4I9 (/ISS) Q61656 (/ISS) |
|
Nucleobase-containing compound metabolic process GO:0006139
Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
|
3 | Q26696 (/ISM) Q580H2 (/ISM) Q580H2 (/ISM) |
|
Protein localization GO:0008104
Any process in which a protein is transported to, or maintained in, a specific location.
|
3 | Q5F485 (/ISS) Q5R7D1 (/ISS) Q810A7 (/ISS) |
|
Regulation of apoptotic process GO:0042981
Any process that modulates the occurrence or rate of cell death by apoptotic process.
|
3 | Q5F485 (/ISS) Q5R7D1 (/ISS) Q810A7 (/ISS) |
|
Regulation of viral genome replication GO:0045069
Any process that modulates the frequency, rate or extent of viral genome replication.
|
3 | Q6AYI1 (/IMP) Q6AYI1 (/IMP) Q6AYI1 (/IMP) |
|
Alternative mRNA splicing, via spliceosome GO:0000380
The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition.
|
2 | Q501J6 (/ISO) Q61656 (/ISO) |
|
Regulation of alternative mRNA splicing, via spliceosome GO:0000381
Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
|
2 | P19109 (/HMP) Q9VXW2 (/HMP) |
|
Regulation of alternative mRNA splicing, via spliceosome GO:0000381
Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
|
2 | Q501J6 (/ISO) Q61656 (/ISO) |
|
Epithelial to mesenchymal transition GO:0001837
A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
|
2 | Q501J6 (/ISO) Q61656 (/ISO) |
|
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
2 | Q501J6 (/ISO) Q61656 (/ISO) |
|
Intracellular estrogen receptor signaling pathway GO:0030520
Any series of molecular signals generated as a consequence of an intracellular estrogen receptor binding to one of its physiological ligands. The pathway begins with receptor-ligand binding, and ends with regulation of a downstream cellular process (e.g. transcription).
|
2 | Q501J6 (/ISO) Q61656 (/ISO) |
|
Androgen receptor signaling pathway GO:0030521
Any series of molecular signals generated as a consequence of an androgen binding to its receptor.
|
2 | Q501J6 (/ISO) Q61656 (/ISO) |
|
Myoblast differentiation GO:0045445
The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers.
|
2 | Q501J6 (/IMP) Q61656 (/IMP) |
|
Pri-miRNA transcription by RNA polymerase II GO:0061614
The cellular synthesis of primary microRNA (pri-miRNA) transcripts from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. pri-miRNA transcripts are subsequently processed to produce the ~22nt miRNAs that function in gene regulation.
|
2 | Q501J6 (/IMP) Q61656 (/IMP) |
|
Regulation of skeletal muscle cell differentiation GO:2001014
Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation.
|
2 | Q61656 (/IMP) Q92841 (/IMP) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
1 | Q61656 (/ISO) |
|
Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184
The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins.
|
1 | P24783 (/IPI) |
|
Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184
The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins.
|
1 | P24782 (/ISO) |
|
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
|
1 | Q4TVV3 (/IMP) |
|
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
|
1 | Q9VXW2 (/ISS) |
|
Nuclear-transcribed mRNA catabolic process GO:0000956
The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells.
|
1 | Q61656 (/ISO) |
|
RRNA processing GO:0006364
Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
|
1 | P24783 (/IMP) |
|
RRNA processing GO:0006364
Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
|
1 | P24782 (/ISO) |
|
RNA processing GO:0006396
Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
|
1 | Q92841 (/TAS) |
|
Protein import into nucleus GO:0006606
The directed movement of a protein from the cytoplasm to the nucleus.
|
1 | Q61656 (/IGI) |
|
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
|
1 | Q4TVV3 (/IMP) |
|
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
|
1 | Q61656 (/IMP) |
|
Protein localization GO:0008104
Any process in which a protein is transported to, or maintained in, a specific location.
|
1 | Q86XP3 (/IDA) |
|
Protein localization GO:0008104
Any process in which a protein is transported to, or maintained in, a specific location.
|
1 | Q810A7 (/ISO) |
|
MRNA transcription GO:0009299
The cellular synthesis of messenger RNA (mRNA) from a DNA template.
|
1 | Q61656 (/ISO) |
|
MiRNA metabolic process GO:0010586
The chemical reactions and pathways involving miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression.
|
1 | Q92841 (/IMP) |
|
MiRNA metabolic process GO:0010586
The chemical reactions and pathways involving miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression.
|
1 | Q501J6 (/ISO) |
|
MiRNA metabolic process GO:0010586
The chemical reactions and pathways involving miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression.
|
1 | Q501J6 (/ISS) |
|
RNA interference GO:0016246
The process in which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation ('silencing') both of transgenes or dsRNA introduced into a germline, and of the host gene(s) homologous to the transgenes or dsRNA. This silencing is triggered by the introduction of transgenes or double-stranded RNA (dsRNA), and can occur through a specific decrease in the level of mRNA, or by negative regulation of translation, of both host genes and transgenes.
|
1 | P19109 (/IMP) |
|
Antimicrobial humoral response GO:0019730
An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus.
|
1 | P19109 (/IMP) |
|
BMP signaling pathway GO:0030509
A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | Q61656 (/ISO) |
|
Exocrine pancreas development GO:0031017
The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells.
|
1 | Q4TVV3 (/IMP) |
|
Regulation of apoptotic process GO:0042981
Any process that modulates the occurrence or rate of cell death by apoptotic process.
|
1 | Q86XP3 (/IMP) |
|
Regulation of apoptotic process GO:0042981
Any process that modulates the occurrence or rate of cell death by apoptotic process.
|
1 | Q810A7 (/ISO) |
|
Positive regulation of DNA damage response, signal transduction by p53 class mediator GO:0043517
Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
|
1 | Q61656 (/ISO) |
|
Regulation of viral genome replication GO:0045069
Any process that modulates the frequency, rate or extent of viral genome replication.
|
1 | Q61656 (/ISO) |
|
MRNA cis splicing, via spliceosome GO:0045292
The joining together, after removal of an intervening sequence composed of one or more introns, of two segments of the same RNA molecule via spliceosomal catalysis to produce an mRNA composed only of exon sequences that all came from the same primary transcript.
|
1 | Q9P7C7 (/ISO) |
|
Positive regulation of lymphocyte differentiation GO:0045621
Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation.
|
1 | Q4TVV3 (/IMP) |
|
Positive regulation of erythrocyte differentiation GO:0045648
Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation.
|
1 | Q4TVV3 (/IMP) |
|
Regulation of osteoblast differentiation GO:0045667
Any process that modulates the frequency, rate or extent of osteoblast differentiation.
|
1 | Q61656 (/IMP) |
|
Negative regulation of Notch signaling pathway GO:0045746
Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.
|
1 | Q9W3M7 (/IGI) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q61656 (/IDA) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q92841 (/IDA) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q501J6 (/ISO) |
|
Digestive tract morphogenesis GO:0048546
The process in which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed.
|
1 | Q4TVV3 (/IMP) |
|
Regulation of defense response to virus GO:0050688
Any process that modulates the frequency, rate or extent of the antiviral response of a cell or organism.
|
1 | P19109 (/IMP) |
|
Definitive hemopoiesis GO:0060216
A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood.
|
1 | Q4TVV3 (/IMP) |
|
Regulation of androgen receptor signaling pathway GO:0060765
Any process that modulates the rate, frequency, or extent of the androgen receptor signaling pathway.
|
1 | Q61656 (/ISO) |
|
Nuclear polyadenylation-dependent mRNA catabolic process GO:0071042
The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA.
|
1 | P24783 (/IGI) |
|
Nuclear polyadenylation-dependent mRNA catabolic process GO:0071042
The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA.
|
1 | P24783 (/IMP) |
|
Intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332
A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, and ends when the execution phase of apoptosis is triggered.
|
1 | Q61656 (/ISO) |
|
Liver morphogenesis GO:0072576
The process in which the anatomical structures of the liver are generated and organized.
|
1 | Q4TVV3 (/IMP) |
|
Positive regulation of hematopoietic stem cell differentiation GO:1902038
Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell differentiation.
|
1 | Q4TVV3 (/IMP) |
|
U2-type prespliceosome assembly GO:1903241
The aggregation, arrangement and bonding together of a set of components to form an U2-type prespliceosome.
|
1 | Q9P7C7 (/IMP) |
|
Positive regulation of production of miRNAs involved in gene silencing by miRNA GO:1903800
Any process that activates or increases the frequency, rate or extent of production of miRNAs involved in gene silencing by miRNA.
|
1 | Q61656 (/ISO) |
|
Messenger ribonucleoprotein complex assembly GO:1990120
The aggregation, arrangement and bonding together of proteins and messenger RNA (mRNA) molecules to form a messenger ribonucleoprotein (mRNP) complex.
|
1 | P24783 (/IMP) |
|
Regulation of skeletal muscle cell differentiation GO:2001014
Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation.
|
1 | Q501J6 (/ISO) |
There are 39 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
39 |
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
(29 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
38 |
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
(28 more) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
37 |
P17844 (/TAS)
P17844 (/TAS)
P17844 (/TAS)
P17844 (/TAS)
P17844 (/TAS)
P17844 (/TAS)
P17844 (/TAS)
P17844 (/TAS)
P17844 (/TAS)
P17844 (/TAS)
(27 more) |
|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
33 |
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
(23 more) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
32 |
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
(22 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
30 |
P17844 (/NAS)
P17844 (/NAS)
P17844 (/NAS)
P17844 (/NAS)
P17844 (/NAS)
P17844 (/NAS)
P17844 (/NAS)
P17844 (/NAS)
P17844 (/NAS)
P17844 (/NAS)
(20 more) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
30 |
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
P17844 (/HDA)
(20 more) |
|
Catalytic step 2 spliceosome GO:0071013
A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs.
|
30 |
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
(20 more) |
|
Ribonucleoprotein complex GO:1990904
A macromolecular complex containing both protein and RNA molecules.
|
30 |
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
P17844 (/IDA)
(20 more) |
|
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
|
11 |
A0A0A0MSJ0 (/IDA)
A0A0C4DG89 (/IDA)
A0A0C4DG89 (/IDA)
A0A0C4DG89 (/IDA)
Q7L014 (/IDA)
Q7L014 (/IDA)
Q7L014 (/IDA)
Q7L014 (/IDA)
Q7L014 (/IDA)
Q86XP3 (/IDA)
(1 more) |
|
Fibrillar center GO:0001650
A structure found most metazoan nucleoli, but not usually found in lower eukaryotes; surrounded by the dense fibrillar component; the zone of transcription from multiple copies of the pre-rRNA genes is in the border region between these two structures.
|
8 | A0A0C4DG89 (/IDA) A0A0C4DG89 (/IDA) A0A0C4DG89 (/IDA) Q7L014 (/IDA) Q7L014 (/IDA) Q7L014 (/IDA) Q7L014 (/IDA) Q7L014 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
8 | A5A6J2 (/ISS) Q4R6M5 (/ISS) Q54CE0 (/ISS) Q5F485 (/ISS) Q5R4I9 (/ISS) Q5R7D1 (/ISS) Q61656 (/ISS) Q810A7 (/ISS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
4 | Q501J6 (/ISO) Q569Z5 (/ISO) Q61656 (/ISO) Q810A7 (/ISO) |
|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
4 | A5A6J2 (/ISS) Q4R6M5 (/ISS) Q5R4I9 (/ISS) Q61656 (/ISS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
4 | Q26696 (/IDA) Q86XP3 (/IDA) Q9C718 (/IDA) Q9C718 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | P19109 (/IC) Q61656 (/IC) Q9VXW2 (/IC) |
|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
3 | Q4Q1K8 (/ISO) Q4QIQ9 (/ISO) Q61656 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
3 | Q5F485 (/ISS) Q5R7D1 (/ISS) Q810A7 (/ISS) |
|
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
|
3 | Q501J6 (/ISO) Q569Z5 (/ISO) Q810A7 (/ISO) |
|
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
|
2 | Q5T1V6 (/IDA) Q9NXZ2 (/IDA) |
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Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
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2 | Q580H2 (/IDA) Q580H2 (/IDA) |
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Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
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2 | P19109 (/HDA) P24783 (/HDA) |
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Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
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2 | P24782 (/HDA) Q9P7C7 (/HDA) |
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Fibrillar center GO:0001650
A structure found most metazoan nucleoli, but not usually found in lower eukaryotes; surrounded by the dense fibrillar component; the zone of transcription from multiple copies of the pre-rRNA genes is in the border region between these two structures.
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1 | Q569Z5 (/ISO) |
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Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
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1 | Q92841 (/TAS) |
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Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
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1 | Q4QIQ9 (/ISO) |
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Spliceosomal complex GO:0005681
Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA.
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1 | Q9VXW2 (/ISS) |
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Polytene chromosome GO:0005700
A type of chromosome in a polyploid cell, formed when multiple copies of homologous chromosomes are aligned side by side to give a giant chromosome in which distinct chromosome bands are readily visible.
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1 | P19109 (/IDA) |
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Polytene chromosome puff GO:0005703
A swelling at a site along the length of a polytene chromosome, thought to be the site of active transcription.
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1 | P19109 (/IDA) |
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Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
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1 | P24782 (/HDA) |
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Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
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1 | Q86XP3 (/IDA) |
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Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
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1 | Q810A7 (/ISO) |
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Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
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1 | P24783 (/HDA) |
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Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
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1 | Q810A7 (/ISO) |
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U2-type prespliceosome GO:0071004
A spliceosomal complex that is formed by association of the 5' splice site with the U1 snRNP, while the branch point sequence is recognized by the U2 snRNP. The prespliceosome includes many proteins in addition to those found in the U1 and U2 snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation.
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1 | Q9P7C7 (/IDA) |
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Precatalytic spliceosome GO:0071011
A spliceosomal complex that is formed by the recruitment of a preassembled U5-containing tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the associated snRNPs.
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1 | P19109 (/HDA) |
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Catalytic step 2 spliceosome GO:0071013
A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs.
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1 | P19109 (/HDA) |
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Catalytic step 2 spliceosome GO:0071013
A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs.
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1 | Q61656 (/ISO) |
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Ribonucleoprotein complex GO:1990904
A macromolecular complex containing both protein and RNA molecules.
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1 | Q61656 (/ISO) |
