The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"P-loop containing nucleotide triphosphate hydrolases
".
FunFam 448: RAB3D, member RAS oncogene family
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | P35276 (/IPI) P35276 (/IPI) Q63942 (/IPI) |
|
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
|
2 | O95716 (/TAS) O95716 (/TAS) |
|
GTP-dependent protein binding GO:0030742
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) when at least one of the interacting partners is in the GTP-bound state.
|
2 | P35276 (/IPI) P35276 (/IPI) |
|
Myosin V binding GO:0031489
Interacting selectively and non-covalently with a class V myosin; myosin V is a dimeric molecule involved in intracellular transport.
|
2 | O95716 (/IPI) O95716 (/IPI) |
|
Myosin V binding GO:0031489
Interacting selectively and non-covalently with a class V myosin; myosin V is a dimeric molecule involved in intracellular transport.
|
2 | P35276 (/ISO) P35276 (/ISO) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of exocytosis GO:0017157
Any process that modulates the frequency, rate or extent of exocytosis.
|
2 | P35276 (/IDA) P35276 (/IDA) |
|
Peptidyl-cysteine methylation GO:0018125
The methylation of peptidyl-cysteine to form peptidyl-S-methyl-L-cysteine.
|
2 | P35276 (/IDA) P35276 (/IDA) |
|
Neutrophil degranulation GO:0043312
The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.
|
2 | O95716 (/TAS) O95716 (/TAS) |
|
Bone resorption GO:0045453
The process in which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the degradation products.
|
2 | O95716 (/IDA) O95716 (/IDA) |
|
Bone resorption GO:0045453
The process in which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the degradation products.
|
2 | P35276 (/ISO) P35276 (/ISO) |
|
Positive regulation of regulated secretory pathway GO:1903307
Any process that activates or increases the frequency, rate or extent of regulated secretory pathway.
|
2 | O95716 (/IMP) O95716 (/IMP) |
|
Positive regulation of regulated secretory pathway GO:1903307
Any process that activates or increases the frequency, rate or extent of regulated secretory pathway.
|
2 | P35276 (/ISO) P35276 (/ISO) |
There are 11 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | P35276 (/HDA) P35276 (/HDA) |
|
Cytoplasmic microtubule GO:0005881
Any microtubule in the cytoplasm of a cell.
|
2 | O95716 (/IDA) O95716 (/IDA) |
|
Cytoplasmic microtubule GO:0005881
Any microtubule in the cytoplasm of a cell.
|
2 | P35276 (/ISO) P35276 (/ISO) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | O95716 (/TAS) O95716 (/TAS) |
|
Transport vesicle GO:0030133
Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell.
|
2 | P35276 (/ISO) P35276 (/ISO) |
|
Azurophil granule membrane GO:0035577
The lipid bilayer surrounding an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.
|
2 | O95716 (/TAS) O95716 (/TAS) |
|
Zymogen granule GO:0042588
A membrane-bounded, cytoplasmic secretory granule found in enzyme-secreting cells and visible by light microscopy. Contain zymogen, an inactive enzyme precursor, often of a digestive enzyme.
|
2 | P35276 (/IDA) P35276 (/IDA) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
2 | O95716 (/HDA) O95716 (/HDA) |
|
Secretory vesicle GO:0099503
A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space.
|
2 | O95716 (/IDA) O95716 (/IDA) |
|
Secretory vesicle GO:0099503
A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space.
|
2 | P35276 (/ISO) P35276 (/ISO) |
|
Transport vesicle GO:0030133
Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell.
|
1 | Q63942 (/IDA) |
