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CATH Superfamily 3.40.50.300

P-loop containing nucleotide triphosphate hydrolases

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 350: RNA polymerase-associated protein RapA

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Bacterial-type RNA polymerase core enzyme binding GO:0001000
Interacting selectively and non-covalently with the bacterial-type RNA polymerase core enzyme, typically consisting of two alpha, one beta, one beta prime, and one omega subunit.
 81 P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA)
(71 more)
Nucleic acid binding GO:0003676
Interacting selectively and non-covalently with any nucleic acid.
 81 P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA)
(71 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 81 P60240 (/IPI) P60240 (/IPI) P60240 (/IPI) P60240 (/IPI) P60240 (/IPI) P60240 (/IPI) P60240 (/IPI) P60240 (/IPI) P60240 (/IPI) P60240 (/IPI)
(71 more)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
 81 P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA)
(71 more)
Helicase activity GO:0004386
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.
 5 Q9KP70 (/ISS) Q9KP70 (/ISS) Q9KP70 (/ISS) Q9KP70 (/ISS) Q9KP70 (/ISS)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
 5 Q9KP70 (/ISS) Q9KP70 (/ISS) Q9KP70 (/ISS) Q9KP70 (/ISS) Q9KP70 (/ISS)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
 81 P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA)
(71 more)
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
 5 Q9KP70 (/ISS) Q9KP70 (/ISS) Q9KP70 (/ISS) Q9KP70 (/ISS) Q9KP70 (/ISS)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
 81 P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA)
(71 more)