The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"alpha/beta hydrolase
".
FunFam 1: Neuroligin 3 isoform
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 27 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
13 |
Q62765 (/IPI)
Q62888 (/IPI)
Q69ZK9 (/IPI)
Q8N0W4 (/IPI)
Q8N0W4 (/IPI)
Q8N0W4 (/IPI)
Q8N0W4 (/IPI)
Q8N0W4 (/IPI)
Q8NFZ3 (/IPI)
Q8NFZ3 (/IPI)
(3 more) |
Neurexin family protein binding GO:0042043
Interacting selectively and non-covalently with neurexins, synaptic cell surface proteins related to latrotoxin receptor, laminin and agrin. Neurexins act as cell recognition molecules at nerve terminals.
|
9 | Q62765 (/IPI) Q62889 (/IPI) Q69ZK9 (/IPI) Q8N0W4 (/IPI) Q8N0W4 (/IPI) Q8N0W4 (/IPI) Q8N0W4 (/IPI) Q8N0W4 (/IPI) Q99K10 (/IPI) |
Scaffold protein binding GO:0097110
Interacting selectively and non-covalently with a scaffold protein. Scaffold proteins are crucial regulators of many key signaling pathways. Although not strictly defined in function, they are known to interact and/or bind with multiple members of a signaling pathway, tethering them into complexes.
|
9 | Q8N0W4 (/IPI) Q8N0W4 (/IPI) Q8N0W4 (/IPI) Q8N0W4 (/IPI) Q8N0W4 (/IPI) Q8NFZ3 (/IPI) Q8NFZ3 (/IPI) Q9NZ94 (/IPI) Q9NZ94 (/IPI) |
Neurexin family protein binding GO:0042043
Interacting selectively and non-covalently with neurexins, synaptic cell surface proteins related to latrotoxin receptor, laminin and agrin. Neurexins act as cell recognition molecules at nerve terminals.
|
8 | B0F2B4 (/ISS) Q62765 (/ISS) Q62888 (/ISS) Q8BYM5 (/ISS) Q8N2Q7 (/ISS) Q8NFZ4 (/ISS) Q9NZ94 (/ISS) Q9NZ94 (/ISS) |
Cell adhesion molecule binding GO:0050839
Interacting selectively and non-covalently with a cell adhesion molecule.
|
7 | Q8N0W4 (/TAS) Q8N0W4 (/TAS) Q8N0W4 (/TAS) Q8N0W4 (/TAS) Q8N0W4 (/TAS) Q8NFZ3 (/TAS) Q8NFZ3 (/TAS) |
Cell adhesion molecule binding GO:0050839
Interacting selectively and non-covalently with a cell adhesion molecule.
|
6 | Q62888 (/ISS) Q8BYM5 (/ISS) Q8N2Q7 (/ISS) Q8NFZ4 (/ISS) Q9NZ94 (/ISS) Q9NZ94 (/ISS) |
Chloride ion binding GO:0031404
Interacting selectively and non-covalently with chloride ions (Cl-).
|
5 | Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) |
Neurexin family protein binding GO:0042043
Interacting selectively and non-covalently with neurexins, synaptic cell surface proteins related to latrotoxin receptor, laminin and agrin. Neurexins act as cell recognition molecules at nerve terminals.
|
5 | Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
5 | Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) |
Signaling receptor activity GO:0038023
Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
|
3 | Q8N2Q7 (/ISS) Q9NZ94 (/ISS) Q9NZ94 (/ISS) |
Cell adhesion molecule binding GO:0050839
Interacting selectively and non-covalently with a cell adhesion molecule.
|
3 | Q62765 (/IPI) Q62889 (/IPI) Q69ZK9 (/IPI) |
Signaling receptor activity GO:0038023
Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
|
2 | Q62765 (/IDA) Q62889 (/IDA) |
Signaling receptor activity GO:0038023
Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
|
2 | Q8BYM5 (/ISO) Q99K10 (/ISO) |
Neurexin family protein binding GO:0042043
Interacting selectively and non-covalently with neurexins, synaptic cell surface proteins related to latrotoxin receptor, laminin and agrin. Neurexins act as cell recognition molecules at nerve terminals.
|
2 | Q8BYM5 (/ISO) Q99K10 (/ISO) |
Neurexin family protein binding GO:0042043
Interacting selectively and non-covalently with neurexins, synaptic cell surface proteins related to latrotoxin receptor, laminin and agrin. Neurexins act as cell recognition molecules at nerve terminals.
|
2 | Q8N2Q7 (/NAS) Q8NFZ4 (/NAS) |
Protein dimerization activity GO:0046983
The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
|
2 | Q8N2Q7 (/ISS) Q99K10 (/ISS) |
Cell adhesion molecule binding GO:0050839
Interacting selectively and non-covalently with a cell adhesion molecule.
|
2 | Q8BYM5 (/ISO) Q99K10 (/ISO) |
Scaffold protein binding GO:0097110
Interacting selectively and non-covalently with a scaffold protein. Scaffold proteins are crucial regulators of many key signaling pathways. Although not strictly defined in function, they are known to interact and/or bind with multiple members of a signaling pathway, tethering them into complexes.
|
2 | Q8BYM5 (/ISO) Q99K10 (/ISO) |
Amyloid-beta binding GO:0001540
Interacting selectively and non-covalently with amyloid-beta peptide/protein and/or its precursor.
|
1 | Q8N2Q7 (/NAS) |
Sulfuric ester hydrolase activity GO:0008484
Catalysis of the reaction: RSO-R' + H2O = RSOOH + R'H. This reaction is the hydrolysis of any sulfuric ester bond, any ester formed from sulfuric acid, O=SO(OH)2.
|
1 | F1N104 (/ISS) |
PDZ domain binding GO:0030165
Interacting selectively and non-covalently with a PDZ domain of a protein, a domain found in diverse signaling proteins.
|
1 | Q8N2Q7 (/IDA) |
PDZ domain binding GO:0030165
Interacting selectively and non-covalently with a PDZ domain of a protein, a domain found in diverse signaling proteins.
|
1 | Q99K10 (/ISO) |
Neurexin family protein binding GO:0042043
Interacting selectively and non-covalently with neurexins, synaptic cell surface proteins related to latrotoxin receptor, laminin and agrin. Neurexins act as cell recognition molecules at nerve terminals.
|
1 | Q99K10 (/IMP) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q69ZK9 (/IPI) |
Protein dimerization activity GO:0046983
The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
|
1 | Q62765 (/IDA) |
Protein dimerization activity GO:0046983
The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
|
1 | Q99K10 (/ISO) |
Scaffold protein binding GO:0097110
Interacting selectively and non-covalently with a scaffold protein. Scaffold proteins are crucial regulators of many key signaling pathways. Although not strictly defined in function, they are known to interact and/or bind with multiple members of a signaling pathway, tethering them into complexes.
|
1 | Q8N2Q7 (/IDA) |
There are 250 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Social behavior GO:0035176
Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group.
|
12 |
B0F2B4 (/IMP)
Q62888 (/IMP)
Q8BYM5 (/IMP)
Q8N0W4 (/IMP)
Q8N0W4 (/IMP)
Q8N0W4 (/IMP)
Q8N0W4 (/IMP)
Q8N0W4 (/IMP)
Q8NFZ3 (/IMP)
Q8NFZ3 (/IMP)
(2 more) |
Presynapse assembly GO:0099054
The aggregation, arrangement and bonding together of a set of components to form a presynapse.
|
11 |
Q8N0W4 (/TAS)
Q8N0W4 (/TAS)
Q8N0W4 (/TAS)
Q8N0W4 (/TAS)
Q8N0W4 (/TAS)
Q8N2Q7 (/TAS)
Q8NFZ3 (/TAS)
Q8NFZ3 (/TAS)
Q8NFZ4 (/TAS)
Q9NZ94 (/TAS)
(1 more) |
Vocalization behavior GO:0071625
The behavior in which an organism produces sounds by a mechanism involving its respiratory system.
|
10 | B0F2B4 (/IMP) Q8N0W4 (/IMP) Q8N0W4 (/IMP) Q8N0W4 (/IMP) Q8N0W4 (/IMP) Q8N0W4 (/IMP) Q8NFZ3 (/IMP) Q8NFZ3 (/IMP) Q9NZ94 (/IMP) Q9NZ94 (/IMP) |
Presynaptic membrane assembly GO:0097105
The aggregation, arrangement and bonding together of a set of components to form a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction.
|
10 | Q62765 (/IDA) Q62888 (/IDA) Q62889 (/IDA) Q69ZK9 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q99K10 (/IDA) |
Learning GO:0007612
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.
|
9 | Q8N0W4 (/IMP) Q8N0W4 (/IMP) Q8N0W4 (/IMP) Q8N0W4 (/IMP) Q8N0W4 (/IMP) Q8NFZ3 (/IMP) Q8NFZ3 (/IMP) Q9NZ94 (/IMP) Q9NZ94 (/IMP) |
Neuron cell-cell adhesion GO:0007158
The attachment of a neuron to another cell via adhesion molecules.
|
8 | Q8N0W4 (/TAS) Q8N0W4 (/TAS) Q8N0W4 (/TAS) Q8N0W4 (/TAS) Q8N0W4 (/TAS) Q8N2Q7 (/TAS) Q8NFZ3 (/TAS) Q8NFZ3 (/TAS) |
Adult behavior GO:0030534
Behavior in a fully developed and mature organism.
|
7 | Q8N0W4 (/IMP) Q8N0W4 (/IMP) Q8N0W4 (/IMP) Q8N0W4 (/IMP) Q8N0W4 (/IMP) Q9NZ94 (/IMP) Q9NZ94 (/IMP) |
Synapse organization GO:0050808
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
|
7 | Q8N0W4 (/IMP) Q8N0W4 (/IMP) Q8N0W4 (/IMP) Q8N0W4 (/IMP) Q8N0W4 (/IMP) Q9NZ94 (/IMP) Q9NZ94 (/IMP) |
Positive regulation of synapse assembly GO:0051965
Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
|
7 | Q69ZK9 (/ISS) Q8BYM5 (/ISS) Q8N2Q7 (/ISS) Q8NFZ4 (/ISS) Q99K10 (/ISS) Q9NZ94 (/ISS) Q9NZ94 (/ISS) |
Positive regulation of synaptic transmission, glutamatergic GO:0051968
Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
|
7 | Q62888 (/ISS) Q62889 (/ISS) Q8N2Q7 (/ISS) Q8NFZ4 (/ISS) Q99K10 (/ISS) Q9NZ94 (/ISS) Q9NZ94 (/ISS) |
Postsynaptic membrane assembly GO:0097104
The aggregation, arrangement and bonding together of a set of components to form a postsynaptic membrane, a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft).
|
7 | Q62765 (/ISS) Q62888 (/ISS) Q62889 (/ISS) Q8N2Q7 (/ISS) Q8NFZ4 (/ISS) Q9NZ94 (/ISS) Q9NZ94 (/ISS) |
Neuron cell-cell adhesion GO:0007158
The attachment of a neuron to another cell via adhesion molecules.
|
6 | Q69ZK9 (/ISS) Q8BYM5 (/ISS) Q8N2Q7 (/ISS) Q8NFZ4 (/ISS) Q9NZ94 (/ISS) Q9NZ94 (/ISS) |
Synapse assembly GO:0007416
The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional).
|
6 | Q62765 (/ISS) Q69ZK9 (/ISS) Q8N2Q7 (/ISS) Q8NFZ4 (/ISS) Q9NZ94 (/ISS) Q9NZ94 (/ISS) |
Modulation of chemical synaptic transmission GO:0050804
Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission.
|
6 | Q62888 (/ISS) Q62889 (/ISS) Q8N2Q7 (/ISS) Q8NFZ4 (/ISS) Q9NZ94 (/ISS) Q9NZ94 (/ISS) |
Presynaptic membrane assembly GO:0097105
The aggregation, arrangement and bonding together of a set of components to form a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction.
|
6 | B0F2B4 (/ISS) Q8BYM5 (/ISS) Q8N2Q7 (/ISS) Q8NFZ4 (/ISS) Q9NZ94 (/ISS) Q9NZ94 (/ISS) |
Positive regulation of excitatory postsynaptic potential GO:2000463
Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
|
6 | Q62888 (/ISS) Q62889 (/ISS) Q8N2Q7 (/ISS) Q8NFZ4 (/ISS) Q9NZ94 (/ISS) Q9NZ94 (/ISS) |
Regulation of respiratory gaseous exchange by nervous system process GO:0002087
A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates.
|
5 | Q62888 (/ISS) Q62889 (/ISS) Q8NFZ4 (/ISS) Q9NZ94 (/ISS) Q9NZ94 (/ISS) |
Brainstem development GO:0003360
The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord.
|
5 | Q8N0W4 (/ISS) Q8N0W4 (/ISS) Q8N0W4 (/ISS) Q8N0W4 (/ISS) Q8N0W4 (/ISS) |
Cerebellum development GO:0021549
The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.
|
5 | Q8N0W4 (/ISS) Q8N0W4 (/ISS) Q8N0W4 (/ISS) Q8N0W4 (/ISS) Q8N0W4 (/ISS) |
Neuron differentiation GO:0030182
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
|
5 | Q8N0W4 (/NAS) Q8N0W4 (/NAS) Q8N0W4 (/NAS) Q8N0W4 (/NAS) Q8N0W4 (/NAS) |
Organ growth GO:0035265
The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function.
|
5 | Q8N0W4 (/ISS) Q8N0W4 (/ISS) Q8N0W4 (/ISS) Q8N0W4 (/ISS) Q8N0W4 (/ISS) |
Cell-cell junction organization GO:0045216
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells.
|
5 | Q8N0W4 (/NAS) Q8N0W4 (/NAS) Q8N0W4 (/NAS) Q8N0W4 (/NAS) Q8N0W4 (/NAS) |
Synapse organization GO:0050808
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
|
5 | Q8N0W4 (/NAS) Q8N0W4 (/NAS) Q8N0W4 (/NAS) Q8N0W4 (/NAS) Q8N0W4 (/NAS) |
Positive regulation of synapse assembly GO:0051965
Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
|
5 | Q62765 (/IDA) Q62888 (/IDA) Q62889 (/IDA) Q8N2Q7 (/IDA) Q99K10 (/IDA) |
Vocalization behavior GO:0071625
The behavior in which an organism produces sounds by a mechanism involving its respiratory system.
|
5 | Q8N0W4 (/ISS) Q8N0W4 (/ISS) Q8N0W4 (/ISS) Q8N0W4 (/ISS) Q8N0W4 (/ISS) |
Negative regulation of excitatory postsynaptic potential GO:0090394
Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
|
5 | Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) |
Regulation of AMPA receptor activity GO:2000311
Any process that modulates the frequency, rate or extent of AMPA selective glutamate receptor activity.
|
5 | Q62888 (/ISS) Q62889 (/ISS) Q8N2Q7 (/ISS) Q8NFZ4 (/ISS) Q99K10 (/ISS) |
Neuron cell-cell adhesion GO:0007158
The attachment of a neuron to another cell via adhesion molecules.
|
4 | Q62765 (/IDA) Q62888 (/IDA) Q62889 (/IDA) Q99K10 (/IDA) |
Synapse assembly GO:0007416
The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional).
|
4 | Q62765 (/IDA) Q62888 (/IDA) Q62889 (/IDA) Q99K10 (/IDA) |
Positive regulation of synaptic transmission, GABAergic GO:0032230
Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).
|
4 | Q62888 (/ISS) Q8N2Q7 (/ISS) Q8NFZ4 (/ISS) Q99K10 (/ISS) |
Protein localization to synapse GO:0035418
Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
|
4 | Q62765 (/ISS) Q62888 (/ISS) Q8N2Q7 (/ISS) Q8NFZ4 (/ISS) |
Positive regulation of dendritic spine development GO:0060999
Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.
|
4 | Q62765 (/IMP) Q62888 (/IMP) Q62889 (/IMP) Q99K10 (/IMP) |
Postsynaptic density protein 95 clustering GO:0097119
The clustering process in which postsynaptic density protein 95 (PSD-95) molecules are localized to distinct domains in the cell membrane. PSD-95 is mostly located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins.
|
4 | Q62765 (/ISS) Q62888 (/ISS) Q8N2Q7 (/ISS) Q8NFZ4 (/ISS) |
Positive regulation of excitatory postsynaptic potential GO:2000463
Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
|
4 | Q62765 (/IMP) Q69ZK9 (/IMP) Q8BYM5 (/IMP) Q99K10 (/IMP) |
Sprouting angiogenesis GO:0002040
The extension of new blood vessels from existing vessels into avascular tissues, this process includes the specialization of endothelial cells into leading tip and stalk cells, proliferation and migration of the endothelial cells and cell adhesion resulting in angiogenic sprout fusion or lumen formation.
|
3 | B6EUL6 (/IGI) D0EVW8 (/IGI) D2X2F9 (/IGI) |
Regulation of respiratory gaseous exchange by nervous system process GO:0002087
A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates.
|
3 | Q69ZK9 (/IGI) Q8BYM5 (/IGI) Q99K10 (/IGI) |
Receptor-mediated endocytosis GO:0006898
An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.
|
3 | Q8BYM5 (/ISS) Q9NZ94 (/ISS) Q9NZ94 (/ISS) |
Neuron cell-cell adhesion GO:0007158
The attachment of a neuron to another cell via adhesion molecules.
|
3 | Q69ZK9 (/ISO) Q8BYM5 (/ISO) Q99K10 (/ISO) |
Synapse assembly GO:0007416
The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional).
|
3 | Q69ZK9 (/ISO) Q8BYM5 (/ISO) Q99K10 (/ISO) |
Axon extension GO:0048675
Long distance growth of a single axon process involved in cellular development.
|
3 | Q8BYM5 (/ISS) Q9NZ94 (/ISS) Q9NZ94 (/ISS) |
Modulation of chemical synaptic transmission GO:0050804
Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission.
|
3 | Q69ZK9 (/IGI) Q8BYM5 (/IGI) Q99K10 (/IGI) |
Synapse organization GO:0050808
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
|
3 | Q62765 (/IDA) Q62888 (/IDA) Q62889 (/IDA) |
Synapse organization GO:0050808
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
|
3 | Q69ZK9 (/ISO) Q8BYM5 (/ISO) Q99K10 (/ISO) |
Positive regulation of synapse assembly GO:0051965
Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
|
3 | Q69ZK9 (/ISO) Q8BYM5 (/ISO) Q99K10 (/ISO) |
Positive regulation of synaptic transmission, glutamatergic GO:0051968
Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
|
3 | Q62765 (/IMP) Q69ZK9 (/IMP) Q8BYM5 (/IMP) |
Rhythmic synaptic transmission GO:0060024
Any process involved in the generation of rhythmic, synchronous synaptic inputs in a neural circuit.
|
3 | Q8BYM5 (/ISS) Q9NZ94 (/ISS) Q9NZ94 (/ISS) |
Positive regulation of dendritic spine development GO:0060999
Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.
|
3 | Q69ZK9 (/ISO) Q8BYM5 (/ISO) Q99K10 (/ISO) |
Terminal button organization GO:0072553
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a terminal button. A terminal button is the terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters.
|
3 | Q62765 (/IMP) Q62888 (/IMP) Q99K10 (/IMP) |
Terminal button organization GO:0072553
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a terminal button. A terminal button is the terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters.
|
3 | Q69ZK9 (/ISS) Q8N2Q7 (/ISS) Q8NFZ4 (/ISS) |
Presynaptic membrane assembly GO:0097105
The aggregation, arrangement and bonding together of a set of components to form a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction.
|
3 | Q69ZK9 (/ISO) Q8BYM5 (/ISO) Q99K10 (/ISO) |
Postsynaptic density protein 95 clustering GO:0097119
The clustering process in which postsynaptic density protein 95 (PSD-95) molecules are localized to distinct domains in the cell membrane. PSD-95 is mostly located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins.
|
3 | Q62765 (/IDA) Q69ZK9 (/IDA) Q99K10 (/IDA) |
Postsynaptic specialization assembly GO:0098698
The aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane.
|
3 | Q62889 (/IDA) Q69ZK9 (/IDA) Q99K10 (/IDA) |
Positive regulation of protein localization to synapse GO:1902474
Any process that activates or increases the frequency, rate or extent of protein localization to synapse.
|
3 | Q62765 (/IMP) Q62888 (/IMP) Q62889 (/IMP) |
Positive regulation of protein localization to synapse GO:1902474
Any process that activates or increases the frequency, rate or extent of protein localization to synapse.
|
3 | Q69ZK9 (/ISO) Q8BYM5 (/ISO) Q99K10 (/ISO) |
Regulation of NMDA receptor activity GO:2000310
Any process that modulates the frequency, rate or extent of N-methyl-D-aspartate selective glutamate receptor activity.
|
3 | Q62765 (/IMP) Q8BYM5 (/IMP) Q99K10 (/IMP) |
Positive regulation of AMPA receptor activity GO:2000969
Any process that activates or increases the frequency, rate or extent of AMPA selective glutamate receptor activity.
|
3 | Q62889 (/ISS) Q9NZ94 (/ISS) Q9NZ94 (/ISS) |
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157
The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell.
|
2 | Q62765 (/ISS) Q8N2Q7 (/ISS) |
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
|
2 | Q62765 (/ISS) Q8N2Q7 (/ISS) |
Positive regulation of circadian sleep/wake cycle, wakefulness GO:0010841
Any process that increases the frequency, or extent of the wakeful phase of the circadian sleep/wake cycle. The wakeful phase is the part of the circadian sleep/wake cycle where the organism is not asleep.
|
2 | Q62765 (/ISS) Q8N2Q7 (/ISS) |
Synaptic vesicle targeting GO:0016080
The process in which synaptic vesicles are directed to specific destination membranes, mediated by molecules at the vesicle membrane and target membrane surfaces.
|
2 | Q62765 (/ISS) Q8N2Q7 (/ISS) |
Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules GO:0016339
The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.
|
2 | Q62765 (/IDA) Q99K10 (/IDA) |
Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules GO:0016339
The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.
|
2 | Q8N2Q7 (/ISS) Q99K10 (/ISS) |
Positive regulation of insulin secretion GO:0032024
Any process that activates or increases the frequency, rate or extent of the regulated release of insulin.
|
2 | Q62888 (/IMP) Q8NFZ4 (/IMP) |
Social behavior GO:0035176
Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group.
|
2 | Q69ZK9 (/ISO) Q8BYM5 (/ISO) |
Social behavior GO:0035176
Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group.
|
2 | Q62889 (/ISS) Q69ZK9 (/ISS) |
Protein localization to synapse GO:0035418
Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
|
2 | Q69ZK9 (/IDA) Q99K10 (/IDA) |
Establishment of protein localization GO:0045184
The directed movement of a protein to a specific location.
|
2 | Q62765 (/ISS) Q8N2Q7 (/ISS) |
Regulation of neuron differentiation GO:0045664
Any process that modulates the frequency, rate or extent of neuron differentiation.
|
2 | Q62765 (/ISS) Q8N2Q7 (/ISS) |
Cytoskeletal matrix organization at active zone GO:0048789
The assembly and arrangement of cytomatrix proteins to form complexes in the cell cortex beneath the active zone, i.e. just beneath the presynaptic plasma membrane.
|
2 | Q62765 (/IMP) Q99K10 (/IMP) |
Synapse organization GO:0050808
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
|
2 | Q8BYM5 (/IGI) Q99K10 (/IGI) |
Synapse organization GO:0050808
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
|
2 | Q69ZK9 (/ISS) Q8NFZ4 (/ISS) |
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
|
2 | Q62765 (/ISS) Q8N2Q7 (/ISS) |
Positive regulation of filopodium assembly GO:0051491
Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
|
2 | Q8N2Q7 (/ISS) Q99K10 (/ISS) |
Inhibitory postsynaptic potential GO:0060080
A process that causes a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.
|
2 | Q9NZ94 (/ISS) Q9NZ94 (/ISS) |
Long-term synaptic potentiation GO:0060291
A process that modulates synaptic plasticity such that synapses are changed resulting in the increase in the rate, or frequency of synaptic transmission at the synapse.
|
2 | Q62765 (/IMP) Q8BYM5 (/IMP) |
Positive regulation of dendritic spine development GO:0060999
Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.
|
2 | Q8N2Q7 (/ISS) Q99K10 (/ISS) |
Negative regulation of dendritic spine morphogenesis GO:0061002
Any process that decreases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.
|
2 | Q8BYM5 (/IMP) Q99K10 (/IMP) |
Terminal button organization GO:0072553
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a terminal button. A terminal button is the terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters.
|
2 | Q69ZK9 (/ISO) Q99K10 (/ISO) |
Synaptic vesicle clustering GO:0097091
The process that results in grouping synaptic vesicles in presynaptic structures.
|
2 | Q62765 (/IDA) Q99K10 (/IDA) |
Synaptic vesicle clustering GO:0097091
The process that results in grouping synaptic vesicles in presynaptic structures.
|
2 | Q62765 (/ISS) Q8N2Q7 (/ISS) |
Postsynaptic membrane assembly GO:0097104
The aggregation, arrangement and bonding together of a set of components to form a postsynaptic membrane, a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft).
|
2 | Q69ZK9 (/IDA) Q99K10 (/IDA) |
AMPA glutamate receptor clustering GO:0097113
The glutamate receptor clustering process in which alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors are localized to distinct domains in the cell membrane.
|
2 | Q62765 (/IMP) Q99K10 (/IMP) |
AMPA glutamate receptor clustering GO:0097113
The glutamate receptor clustering process in which alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors are localized to distinct domains in the cell membrane.
|
2 | Q62765 (/ISS) Q8N2Q7 (/ISS) |
NMDA glutamate receptor clustering GO:0097114
The receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane.
|
2 | Q8N2Q7 (/ISS) Q99K10 (/ISS) |
Neurexin clustering involved in presynaptic membrane assembly GO:0097115
The receptor clustering process involved in assembly of the presynaptic membrane in which neurexins are localized to distinct domains in the cell membrane. Neurexins are synaptic cell surface proteins which act as cell recognition molecules at nerve terminals.
|
2 | Q62765 (/ISS) Q8N2Q7 (/ISS) |
Gephyrin clustering involved in postsynaptic density assembly GO:0097116
The clustering process in which gephyrin molecules are localized to distinct domains in the postsynaptic density as part of postsynaptic density assembly. Gephyrin is a component of the postsynaptic protein network of inhibitory synapses.
|
2 | Q62888 (/ISS) Q8NFZ4 (/ISS) |
Receptor localization to synapse GO:0097120
Any process in which a receptor is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
|
2 | Q62765 (/ISS) Q8N2Q7 (/ISS) |
Positive regulation of inhibitory postsynaptic potential GO:0097151
Any process that activates or increases the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.
|
2 | Q62888 (/IMP) Q69ZK9 (/IMP) |
Positive regulation of inhibitory postsynaptic potential GO:0097151
Any process that activates or increases the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.
|
2 | Q69ZK9 (/ISO) Q8BYM5 (/ISO) |
Postsynaptic specialization assembly GO:0098698
The aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane.
|
2 | Q69ZK9 (/IMP) Q99K10 (/IMP) |
Positive regulation of synaptic vesicle endocytosis GO:1900244
Any process that activates or increases the frequency, rate or extent of synaptic vesicle endocytosis.
|
2 | Q62765 (/IMP) Q99K10 (/IMP) |
Positive regulation of synaptic vesicle exocytosis GO:2000302
Any process that activates or increases the frequency, rate or extent of synaptic vesicle exocytosis.
|
2 | Q62765 (/IMP) Q99K10 (/IMP) |
Regulation of NMDA receptor activity GO:2000310
Any process that modulates the frequency, rate or extent of N-methyl-D-aspartate selective glutamate receptor activity.
|
2 | Q62765 (/IDA) Q99K10 (/IDA) |
Regulation of NMDA receptor activity GO:2000310
Any process that modulates the frequency, rate or extent of N-methyl-D-aspartate selective glutamate receptor activity.
|
2 | Q62889 (/ISS) Q8N2Q7 (/ISS) |
Regulation of AMPA receptor activity GO:2000311
Any process that modulates the frequency, rate or extent of AMPA selective glutamate receptor activity.
|
2 | Q69ZK9 (/IMP) Q8BYM5 (/IMP) |
Positive regulation of excitatory postsynaptic potential GO:2000463
Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
|
2 | Q62765 (/IDA) Q99K10 (/IDA) |
Positive regulation of synaptic vesicle clustering GO:2000809
Any process that activates or increases the frequency, rate or extent of synaptic vesicle clustering.
|
2 | Q69ZK9 (/IDA) Q99K10 (/IDA) |
Thigmotaxis GO:0001966
The directed movement of a motile cell or organism in response to touch.
|
1 | Q62888 (/IMP) |
Thigmotaxis GO:0001966
The directed movement of a motile cell or organism in response to touch.
|
1 | Q69ZK9 (/ISO) |
Thigmotaxis GO:0001966
The directed movement of a motile cell or organism in response to touch.
|
1 | Q69ZK9 (/ISS) |
Territorial aggressive behavior GO:0002124
Aggressive behavior performed in defence of a fixed area against intruders, typically conspecifics.
|
1 | B0F2B4 (/IMP) |
Brainstem development GO:0003360
The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord.
|
1 | B0F2B4 (/IMP) |
Protein targeting GO:0006605
The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
|
1 | Q62765 (/IDA) |
Protein targeting GO:0006605
The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
|
1 | Q99K10 (/ISO) |
Protein targeting GO:0006605
The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
|
1 | Q8N2Q7 (/ISS) |
Receptor-mediated endocytosis GO:0006898
An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.
|
1 | Q62889 (/IDA) |
Receptor-mediated endocytosis GO:0006898
An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.
|
1 | Q8BYM5 (/ISO) |
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157
The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell.
|
1 | Q99K10 (/IDA) |
Neuron cell-cell adhesion GO:0007158
The attachment of a neuron to another cell via adhesion molecules.
|
1 | Q8N2Q7 (/NAS) |
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
|
1 | Q99K10 (/IDA) |
Synapse assembly GO:0007416
The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional).
|
1 | Q8NFZ4 (/NAS) |
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
|
1 | Q62888 (/IEP) |
Learning GO:0007612
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.
|
1 | Q8BYM5 (/ISO) |
Jump response GO:0007630
The sudden, usually upward, movement off the ground or other surface through sudden muscular effort in the legs, following exposure to an external stimulus.
|
1 | Q62888 (/IMP) |
Jump response GO:0007630
The sudden, usually upward, movement off the ground or other surface through sudden muscular effort in the legs, following exposure to an external stimulus.
|
1 | Q69ZK9 (/ISO) |
Jump response GO:0007630
The sudden, usually upward, movement off the ground or other surface through sudden muscular effort in the legs, following exposure to an external stimulus.
|
1 | Q69ZK9 (/ISS) |
Male courtship behavior GO:0008049
The behavior of a male, for the purpose of attracting a sexual partner. An example of this process is found in Drosophila melanogaster.
|
1 | B0F2B4 (/IMP) |
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
1 | Q62888 (/IDA) |
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
1 | Q69ZK9 (/ISO) |
Visual learning GO:0008542
Any process in an organism in which a change in behavior of an individual occurs in response to repeated exposure to a visual cue.
|
1 | Q8BYM5 (/IMP) |
Positive regulation of circadian sleep/wake cycle, wakefulness GO:0010841
Any process that increases the frequency, or extent of the wakeful phase of the circadian sleep/wake cycle. The wakeful phase is the part of the circadian sleep/wake cycle where the organism is not asleep.
|
1 | Q99K10 (/IMP) |
Synaptic vesicle targeting GO:0016080
The process in which synaptic vesicles are directed to specific destination membranes, mediated by molecules at the vesicle membrane and target membrane surfaces.
|
1 | Q99K10 (/IMP) |
Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules GO:0016339
The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.
|
1 | Q99K10 (/ISO) |
Sensory perception of pain GO:0019233
The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process.
|
1 | Q69ZK9 (/IMP) |
Sensory perception of pain GO:0019233
The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process.
|
1 | Q62888 (/ISS) |
Cerebellum development GO:0021549
The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.
|
1 | B0F2B4 (/IMP) |
Neuronal signal transduction GO:0023041
The process in which an activated neuronal cell receptor conveys information down a signaling pathway, resulting in a change in the function or state of a cell. This process may be intracellular or intercellular.
|
1 | Q8N2Q7 (/TAS) |
Adult behavior GO:0030534
Behavior in a fully developed and mature organism.
|
1 | Q8BYM5 (/ISO) |
Neuron projection development GO:0031175
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
|
1 | Q8N2Q7 (/IDA) |
Neuron projection development GO:0031175
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
|
1 | Q62765 (/IGI) |
Neuron projection development GO:0031175
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
|
1 | Q99K10 (/ISO) |
Neuron projection development GO:0031175
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
|
1 | Q8N2Q7 (/ISS) |
Positive regulation of insulin secretion GO:0032024
Any process that activates or increases the frequency, rate or extent of the regulated release of insulin.
|
1 | Q62888 (/IDA) |
Positive regulation of insulin secretion GO:0032024
Any process that activates or increases the frequency, rate or extent of the regulated release of insulin.
|
1 | Q69ZK9 (/ISO) |
Positive regulation of synaptic transmission, GABAergic GO:0032230
Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).
|
1 | Q62765 (/IDA) |
Positive regulation of synaptic transmission, GABAergic GO:0032230
Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).
|
1 | Q69ZK9 (/IMP) |
Positive regulation of synaptic transmission, GABAergic GO:0032230
Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).
|
1 | Q99K10 (/ISO) |
Organ growth GO:0035265
The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function.
|
1 | B0F2B4 (/IMP) |
Locomotory exploration behavior GO:0035641
The specific movement from place to place of an organism in response to a novel environment.
|
1 | Q69ZK9 (/IMP) |
Locomotory exploration behavior GO:0035641
The specific movement from place to place of an organism in response to a novel environment.
|
1 | Q62888 (/ISS) |
Neuronal ion channel clustering GO:0045161
The process in which voltage-gated ion channels become localized to distinct subcellular domains in the neuron. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation.
|
1 | Q62765 (/TAS) |
Establishment of protein localization GO:0045184
The directed movement of a protein to a specific location.
|
1 | Q99K10 (/IMP) |
Cell-cell junction maintenance GO:0045217
The maintenance of junctions between cells.
|
1 | Q8NFZ4 (/NAS) |
Regulation of neuron differentiation GO:0045664
Any process that modulates the frequency, rate or extent of neuron differentiation.
|
1 | Q99K10 (/IDA) |
Synaptic vesicle transport GO:0048489
The directed movement of synaptic vesicles.
|
1 | Q62765 (/IMP) |
Synaptic vesicle transport GO:0048489
The directed movement of synaptic vesicles.
|
1 | Q99K10 (/ISO) |
Axon extension GO:0048675
Long distance growth of a single axon process involved in cellular development.
|
1 | Q62889 (/IMP) |
Axon extension GO:0048675
Long distance growth of a single axon process involved in cellular development.
|
1 | Q8BYM5 (/ISO) |
Oligodendrocyte differentiation GO:0048709
The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system.
|
1 | Q8BYM5 (/IMP) |
Cytoskeletal matrix organization at active zone GO:0048789
The assembly and arrangement of cytomatrix proteins to form complexes in the cell cortex beneath the active zone, i.e. just beneath the presynaptic plasma membrane.
|
1 | Q99K10 (/ISO) |
Cytoskeletal matrix organization at active zone GO:0048789
The assembly and arrangement of cytomatrix proteins to form complexes in the cell cortex beneath the active zone, i.e. just beneath the presynaptic plasma membrane.
|
1 | Q8N2Q7 (/ISS) |
Modulation of chemical synaptic transmission GO:0050804
Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission.
|
1 | Q62765 (/IMP) |
Modulation of chemical synaptic transmission GO:0050804
Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission.
|
1 | Q99K10 (/ISO) |
Neuromuscular process controlling balance GO:0050885
Any process that an organism uses to control its balance, the orientation of the organism (or the head of the organism) in relation to the source of gravity. In humans and animals, balance is perceived through visual cues, the labyrinth system of the inner ears and information from skin pressure receptors and muscle and joint receptors.
|
1 | Q69ZK9 (/IMP) |
Neuromuscular process controlling balance GO:0050885
Any process that an organism uses to control its balance, the orientation of the organism (or the head of the organism) in relation to the source of gravity. In humans and animals, balance is perceived through visual cues, the labyrinth system of the inner ears and information from skin pressure receptors and muscle and joint receptors.
|
1 | Q62888 (/ISS) |
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
|
1 | Q99K10 (/IDA) |
Protein heterotetramerization GO:0051290
The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical.
|
1 | Q62765 (/IDA) |
Protein heterotetramerization GO:0051290
The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical.
|
1 | Q99K10 (/ISO) |
Positive regulation of filopodium assembly GO:0051491
Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
|
1 | Q62765 (/IDA) |
Positive regulation of filopodium assembly GO:0051491
Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
|
1 | Q99K10 (/ISO) |
Positive regulation of synapse assembly GO:0051965
Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
|
1 | Q8BYM5 (/IMP) |
Regulation of synaptic transmission, glutamatergic GO:0051966
Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
|
1 | Q8BYM5 (/IMP) |
Regulation of synaptic transmission, glutamatergic GO:0051966
Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
|
1 | Q62889 (/ISS) |
Positive regulation of synaptic transmission, glutamatergic GO:0051968
Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
|
1 | Q62765 (/IDA) |
Positive regulation of synaptic transmission, glutamatergic GO:0051968
Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
|
1 | Q99K10 (/ISO) |
Rhythmic synaptic transmission GO:0060024
Any process involved in the generation of rhythmic, synchronous synaptic inputs in a neural circuit.
|
1 | Q62889 (/IMP) |
Rhythmic synaptic transmission GO:0060024
Any process involved in the generation of rhythmic, synchronous synaptic inputs in a neural circuit.
|
1 | Q8BYM5 (/ISO) |
Excitatory postsynaptic potential GO:0060079
A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
|
1 | Q8BYM5 (/IMP) |
Excitatory postsynaptic potential GO:0060079
A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
|
1 | Q62889 (/ISS) |
Inhibitory postsynaptic potential GO:0060080
A process that causes a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.
|
1 | Q62889 (/IDA) |
Inhibitory postsynaptic potential GO:0060080
A process that causes a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.
|
1 | Q8BYM5 (/IMP) |
Inhibitory postsynaptic potential GO:0060080
A process that causes a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.
|
1 | Q8BYM5 (/ISO) |
Long-term synaptic potentiation GO:0060291
A process that modulates synaptic plasticity such that synapses are changed resulting in the increase in the rate, or frequency of synaptic transmission at the synapse.
|
1 | Q99K10 (/ISO) |
Positive regulation of dendritic spine development GO:0060999
Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.
|
1 | Q62765 (/IDA) |
Positive regulation of dendritic spine development GO:0060999
Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.
|
1 | Q8N2Q7 (/IGI) |
Regulation of dendritic spine morphogenesis GO:0061001
Any process that modulates the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.
|
1 | Q8BYM5 (/IMP) |
Regulation of dendritic spine morphogenesis GO:0061001
Any process that modulates the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.
|
1 | Q62889 (/ISS) |
Negative regulation of dendritic spine morphogenesis GO:0061002
Any process that decreases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.
|
1 | Q8N2Q7 (/IGI) |
Negative regulation of dendritic spine morphogenesis GO:0061002
Any process that decreases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.
|
1 | Q99K10 (/ISO) |
Negative regulation of dendritic spine morphogenesis GO:0061002
Any process that decreases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.
|
1 | Q62765 (/ISS) |
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
1 | Q62765 (/IDA) |
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
1 | Q99K10 (/ISO) |
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
1 | Q8N2Q7 (/ISS) |
Vocalization behavior GO:0071625
The behavior in which an organism produces sounds by a mechanism involving its respiratory system.
|
1 | Q8BYM5 (/ISO) |
Negative regulation of excitatory postsynaptic potential GO:0090394
Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
|
1 | Q8BYM5 (/IMP) |
Negative regulation of excitatory postsynaptic potential GO:0090394
Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
|
1 | B0F2B4 (/ISS) |
Synaptic vesicle clustering GO:0097091
The process that results in grouping synaptic vesicles in presynaptic structures.
|
1 | Q62765 (/IMP) |
Synaptic vesicle clustering GO:0097091
The process that results in grouping synaptic vesicles in presynaptic structures.
|
1 | Q99K10 (/ISO) |
Postsynaptic membrane assembly GO:0097104
The aggregation, arrangement and bonding together of a set of components to form a postsynaptic membrane, a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft).
|
1 | Q8BYM5 (/IMP) |
Presynaptic membrane assembly GO:0097105
The aggregation, arrangement and bonding together of a set of components to form a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction.
|
1 | Q69ZK9 (/IMP) |
AMPA glutamate receptor clustering GO:0097113
The glutamate receptor clustering process in which alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors are localized to distinct domains in the cell membrane.
|
1 | Q99K10 (/IDA) |
AMPA glutamate receptor clustering GO:0097113
The glutamate receptor clustering process in which alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors are localized to distinct domains in the cell membrane.
|
1 | Q99K10 (/ISO) |
NMDA glutamate receptor clustering GO:0097114
The receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane.
|
1 | Q62765 (/IDA) |
NMDA glutamate receptor clustering GO:0097114
The receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane.
|
1 | Q99K10 (/ISO) |
Neurexin clustering involved in presynaptic membrane assembly GO:0097115
The receptor clustering process involved in assembly of the presynaptic membrane in which neurexins are localized to distinct domains in the cell membrane. Neurexins are synaptic cell surface proteins which act as cell recognition molecules at nerve terminals.
|
1 | Q99K10 (/IDA) |
Gephyrin clustering involved in postsynaptic density assembly GO:0097116
The clustering process in which gephyrin molecules are localized to distinct domains in the postsynaptic density as part of postsynaptic density assembly. Gephyrin is a component of the postsynaptic protein network of inhibitory synapses.
|
1 | Q69ZK9 (/IDA) |
Postsynaptic density protein 95 clustering GO:0097119
The clustering process in which postsynaptic density protein 95 (PSD-95) molecules are localized to distinct domains in the cell membrane. PSD-95 is mostly located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins.
|
1 | Q62765 (/IMP) |
Postsynaptic density protein 95 clustering GO:0097119
The clustering process in which postsynaptic density protein 95 (PSD-95) molecules are localized to distinct domains in the cell membrane. PSD-95 is mostly located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins.
|
1 | Q99K10 (/ISO) |
Receptor localization to synapse GO:0097120
Any process in which a receptor is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
|
1 | Q99K10 (/IDA) |
Positive regulation of inhibitory postsynaptic potential GO:0097151
Any process that activates or increases the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.
|
1 | Q62889 (/IDA) |
Positive regulation of inhibitory postsynaptic potential GO:0097151
Any process that activates or increases the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.
|
1 | Q8NFZ4 (/ISS) |
Cell-cell adhesion GO:0098609
The attachment of one cell to another cell via adhesion molecules.
|
1 | Q8NFZ4 (/NAS) |
Postsynaptic specialization assembly GO:0098698
The aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane.
|
1 | Q8BYM5 (/ISO) |
Retrograde trans-synaptic signaling by trans-synaptic protein complex GO:0098942
Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by trans-synaptic protein complex.
|
1 | Q62765 (/IMP) |
Retrograde trans-synaptic signaling by trans-synaptic protein complex GO:0098942
Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by trans-synaptic protein complex.
|
1 | Q99K10 (/ISO) |
Regulation of presynapse organization GO:0099174
Any process that modulates the physical form of a presynapse.
|
1 | Q62765 (/EXP) |
Regulation of presynapse organization GO:0099174
Any process that modulates the physical form of a presynapse.
|
1 | Q62765 (/IDA) |
Regulation of presynapse organization GO:0099174
Any process that modulates the physical form of a presynapse.
|
1 | Q62765 (/IMP) |
Regulation of presynapse organization GO:0099174
Any process that modulates the physical form of a presynapse.
|
1 | Q99K10 (/ISO) |
Synaptic membrane adhesion GO:0099560
The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane.
|
1 | Q99K10 (/IDA) |
Synaptic membrane adhesion GO:0099560
The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane.
|
1 | Q99K10 (/IMP) |
Neuron projection arborization GO:0140058
The process in which the anatomical structures of a neuron projection are generated and organized into branches. A neuron projection is any process extending from a neural cell, such as axons or dendrites.
|
1 | Q62765 (/IGI) |
Neuron projection arborization GO:0140058
The process in which the anatomical structures of a neuron projection are generated and organized into branches. A neuron projection is any process extending from a neural cell, such as axons or dendrites.
|
1 | Q99K10 (/ISO) |
Neuron projection arborization GO:0140058
The process in which the anatomical structures of a neuron projection are generated and organized into branches. A neuron projection is any process extending from a neural cell, such as axons or dendrites.
|
1 | Q8N2Q7 (/ISS) |
Positive regulation of ruffle assembly GO:1900029
Any process that activates or increases the frequency, rate or extent of ruffle assembly.
|
1 | Q62765 (/IDA) |
Positive regulation of ruffle assembly GO:1900029
Any process that activates or increases the frequency, rate or extent of ruffle assembly.
|
1 | Q99K10 (/ISO) |
Positive regulation of ruffle assembly GO:1900029
Any process that activates or increases the frequency, rate or extent of ruffle assembly.
|
1 | Q8N2Q7 (/ISS) |
Positive regulation of synaptic vesicle endocytosis GO:1900244
Any process that activates or increases the frequency, rate or extent of synaptic vesicle endocytosis.
|
1 | Q99K10 (/ISO) |
Positive regulation of synaptic vesicle endocytosis GO:1900244
Any process that activates or increases the frequency, rate or extent of synaptic vesicle endocytosis.
|
1 | Q8N2Q7 (/ISS) |
Regulation of long-term synaptic potentiation GO:1900271
Any process that modulates the frequency, rate or extent of long-term synaptic potentiation.
|
1 | Q8BYM5 (/IMP) |
Regulation of long-term synaptic potentiation GO:1900271
Any process that modulates the frequency, rate or extent of long-term synaptic potentiation.
|
1 | Q62889 (/ISS) |
Insulin metabolic process GO:1901142
The chemical reactions and pathways involving insulin.
|
1 | Q62888 (/IDA) |
Insulin metabolic process GO:1901142
The chemical reactions and pathways involving insulin.
|
1 | Q69ZK9 (/ISO) |
Positive regulation of protein localization to synapse GO:1902474
Any process that activates or increases the frequency, rate or extent of protein localization to synapse.
|
1 | Q8NFZ4 (/IDA) |
Positive regulation of intracellular signal transduction GO:1902533
Any process that activates or increases the frequency, rate or extent of intracellular signal transduction.
|
1 | Q62765 (/IDA) |
Positive regulation of intracellular signal transduction GO:1902533
Any process that activates or increases the frequency, rate or extent of intracellular signal transduction.
|
1 | Q99K10 (/ISO) |
Positive regulation of intracellular signal transduction GO:1902533
Any process that activates or increases the frequency, rate or extent of intracellular signal transduction.
|
1 | Q8N2Q7 (/ISS) |
Positive regulation of t-SNARE clustering GO:1904034
Any process that activates or increases the frequency, rate or extent of t-SNARE clustering.
|
1 | Q62888 (/IDA) |
Positive regulation of t-SNARE clustering GO:1904034
Any process that activates or increases the frequency, rate or extent of t-SNARE clustering.
|
1 | Q69ZK9 (/ISO) |
Excitatory synapse assembly GO:1904861
The aggregation, arrangement and bonding together of a set of components to form an excitatory synapse.
|
1 | Q99K10 (/IDA) |
Excitatory synapse assembly GO:1904861
The aggregation, arrangement and bonding together of a set of components to form an excitatory synapse.
|
1 | Q99K10 (/IMP) |
Excitatory synapse assembly GO:1904861
The aggregation, arrangement and bonding together of a set of components to form an excitatory synapse.
|
1 | Q8N2Q7 (/ISS) |
Inhibitory synapse assembly GO:1904862
The aggregation, arrangement and bonding together of a set of components to form an inhibitory synapse.
|
1 | Q69ZK9 (/IDA) |
Positive regulation of presynaptic active zone assembly GO:1905520
Any process that activates or increases the frequency, rate or extent of presynaptic active zone assembly.
|
1 | Q62765 (/IDA) |
Positive regulation of presynaptic active zone assembly GO:1905520
Any process that activates or increases the frequency, rate or extent of presynaptic active zone assembly.
|
1 | Q99K10 (/ISO) |
Regulation of presynapse assembly GO:1905606
Any process that modulates the frequency, rate or extent of presynapse assembly.
|
1 | Q62888 (/IDA) |
Regulation of presynapse assembly GO:1905606
Any process that modulates the frequency, rate or extent of presynapse assembly.
|
1 | Q62888 (/IMP) |
Regulation of presynapse assembly GO:1905606
Any process that modulates the frequency, rate or extent of presynapse assembly.
|
1 | Q69ZK9 (/ISO) |
Positive regulation of synaptic vesicle exocytosis GO:2000302
Any process that activates or increases the frequency, rate or extent of synaptic vesicle exocytosis.
|
1 | Q99K10 (/ISO) |
Positive regulation of synaptic vesicle exocytosis GO:2000302
Any process that activates or increases the frequency, rate or extent of synaptic vesicle exocytosis.
|
1 | Q8N2Q7 (/ISS) |
Regulation of NMDA receptor activity GO:2000310
Any process that modulates the frequency, rate or extent of N-methyl-D-aspartate selective glutamate receptor activity.
|
1 | Q8N2Q7 (/IGI) |
Regulation of NMDA receptor activity GO:2000310
Any process that modulates the frequency, rate or extent of N-methyl-D-aspartate selective glutamate receptor activity.
|
1 | Q99K10 (/ISO) |
Regulation of AMPA receptor activity GO:2000311
Any process that modulates the frequency, rate or extent of AMPA selective glutamate receptor activity.
|
1 | Q62765 (/IDA) |
Regulation of AMPA receptor activity GO:2000311
Any process that modulates the frequency, rate or extent of AMPA selective glutamate receptor activity.
|
1 | Q99K10 (/ISO) |
Regulation of terminal button organization GO:2000331
Any process that modulates the frequency, rate or extent of terminal button organization.
|
1 | Q8BYM5 (/IMP) |
Regulation of terminal button organization GO:2000331
Any process that modulates the frequency, rate or extent of terminal button organization.
|
1 | Q62889 (/ISS) |
Positive regulation of excitatory postsynaptic potential GO:2000463
Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
|
1 | Q8N2Q7 (/IGI) |
Positive regulation of excitatory postsynaptic potential GO:2000463
Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
|
1 | Q99K10 (/ISO) |
Positive regulation of synaptic vesicle clustering GO:2000809
Any process that activates or increases the frequency, rate or extent of synaptic vesicle clustering.
|
1 | Q8BYM5 (/IMP) |
Positive regulation of AMPA receptor activity GO:2000969
Any process that activates or increases the frequency, rate or extent of AMPA selective glutamate receptor activity.
|
1 | Q8BYM5 (/IMP) |
There are 74 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
12 |
Q62765 (/TAS)
Q8N0W4 (/TAS)
Q8N0W4 (/TAS)
Q8N0W4 (/TAS)
Q8N0W4 (/TAS)
Q8N0W4 (/TAS)
Q8N2Q7 (/TAS)
Q8NFZ3 (/TAS)
Q8NFZ3 (/TAS)
Q8NFZ4 (/TAS)
(2 more) |
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
11 |
Q62765 (/IDA)
Q62888 (/IDA)
Q62889 (/IDA)
Q8N0W4 (/IDA)
Q8N0W4 (/IDA)
Q8N0W4 (/IDA)
Q8N0W4 (/IDA)
Q8N0W4 (/IDA)
Q99K10 (/IDA)
Q9NZ94 (/IDA)
(1 more) |
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
|
11 |
Q62888 (/ISS)
Q8N0W4 (/ISS)
Q8N0W4 (/ISS)
Q8N0W4 (/ISS)
Q8N0W4 (/ISS)
Q8N0W4 (/ISS)
Q8N2Q7 (/ISS)
Q8NFZ4 (/ISS)
Q99K10 (/ISS)
Q9NZ94 (/ISS)
(1 more) |
Spanning component of membrane GO:0089717
The component of a membrane consisting of gene products and protein complexes that have some part that spans both leaflets of the membrane.
|
11 |
Q8N0W4 (/TAS)
Q8N0W4 (/TAS)
Q8N0W4 (/TAS)
Q8N0W4 (/TAS)
Q8N0W4 (/TAS)
Q8N2Q7 (/TAS)
Q8NFZ3 (/TAS)
Q8NFZ3 (/TAS)
Q8NFZ4 (/TAS)
Q9NZ94 (/TAS)
(1 more) |
Symmetric, GABA-ergic, inhibitory synapse GO:0098983
A neuron to neuron synapse that lacks an electron dense postsynaptic specialization, uses GABA as a neurotransmitter and whose activity results in inhibitory postsynaptic potentials.
|
10 | Q8N0W4 (/TAS) Q8N0W4 (/TAS) Q8N0W4 (/TAS) Q8N0W4 (/TAS) Q8N0W4 (/TAS) Q8NFZ3 (/TAS) Q8NFZ3 (/TAS) Q8NFZ4 (/TAS) Q9NZ94 (/TAS) Q9NZ94 (/TAS) |
Asymmetric, glutamatergic, excitatory synapse GO:0098985
A neuron to neuron synapse with a postsynaptic density, that uses glutamate as a neurotransmitter and whose activity results in excitatory postsynaptic potentials.
|
10 | Q8N0W4 (/TAS) Q8N0W4 (/TAS) Q8N0W4 (/TAS) Q8N0W4 (/TAS) Q8N0W4 (/TAS) Q8N2Q7 (/TAS) Q8NFZ3 (/TAS) Q8NFZ3 (/TAS) Q9NZ94 (/TAS) Q9NZ94 (/TAS) |
Excitatory synapse GO:0060076
A synapse in which an action potential in the presynaptic cell increases the probability of an action potential occurring in the postsynaptic cell.
|
9 | Q62888 (/IDA) Q62889 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q9NZ94 (/IDA) Q9NZ94 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
8 | B0F2B4 (/IDA) Q62765 (/IDA) Q62888 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) |
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
6 | B0F2B4 (/ISS) Q69ZK9 (/ISS) Q8BYM5 (/ISS) Q8N2Q7 (/ISS) Q8NFZ4 (/ISS) Q99K10 (/ISS) |
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
|
6 | Q62765 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
5 | Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) Q8N0W4 (/IDA) |
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
5 | Q8N0W4 (/NAS) Q8N0W4 (/NAS) Q8N0W4 (/NAS) Q8N0W4 (/NAS) Q8N0W4 (/NAS) |
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
|
5 | B0F2B4 (/IDA) Q62765 (/IDA) Q62889 (/IDA) Q69ZK9 (/IDA) Q99K10 (/IDA) |
Integral component of postsynaptic membrane GO:0099055
The component of the postsynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
5 | Q69ZK9 (/ISS) Q8BYM5 (/ISS) Q8NFZ4 (/ISS) Q9NZ94 (/ISS) Q9NZ94 (/ISS) |
Integral component of postsynaptic specialization membrane GO:0099060
The component of the postsynaptic specialization membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
5 | B0F2B4 (/IDA) Q62765 (/IDA) Q62888 (/IDA) Q62889 (/IDA) Q69ZK9 (/IDA) |
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
3 | Q69ZK9 (/ISO) Q8BYM5 (/ISO) Q99K10 (/ISO) |
Endocytic vesicle GO:0030139
A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. Endocytic vesicles fuse with early endosomes to deliver the cargo for further sorting.
|
3 | Q8BYM5 (/ISS) Q9NZ94 (/ISS) Q9NZ94 (/ISS) |
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
|
3 | B0F2B4 (/ISS) Q8N2Q7 (/ISS) Q99K10 (/ISS) |
Excitatory synapse GO:0060076
A synapse in which an action potential in the presynaptic cell increases the probability of an action potential occurring in the postsynaptic cell.
|
3 | Q62765 (/IC) Q69ZK9 (/IC) Q99K10 (/IC) |
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
|
3 | Q62765 (/IDA) Q62889 (/IDA) Q99K10 (/IDA) |
GABA-ergic synapse GO:0098982
A synapse that uses GABA as a neurotransmitter. These synapses are typically inhibitory.
|
3 | Q62888 (/IDA) Q62889 (/IDA) Q69ZK9 (/IDA) |
Integral component of postsynaptic specialization membrane GO:0099060
The component of the postsynaptic specialization membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
3 | Q69ZK9 (/ISO) Q8BYM5 (/ISO) Q99K10 (/ISO) |
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
|
2 | Q8N2Q7 (/ISS) Q99K10 (/ISS) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | Q69ZK9 (/ISO) Q99K10 (/ISO) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q62765 (/ISS) Q8N2Q7 (/ISS) |
Filopodium tip GO:0032433
The end of a filopodium distal to the body of the cell.
|
2 | Q8N2Q7 (/ISS) Q99K10 (/ISS) |
Dendritic spine GO:0043197
A small, membranous protrusion from a dendrite that forms a postsynaptic compartment - typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable including \thin\, \stubby\, \mushroom\, and \branched\, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.
|
2 | Q8N2Q7 (/ISS) Q99K10 (/ISS) |
Dendritic shaft GO:0043198
Cylindric portion of the dendrite, directly stemming from the perikaryon, and carrying the dendritic spines.
|
2 | Q62765 (/IDA) Q62888 (/IDA) |
Dendritic shaft GO:0043198
Cylindric portion of the dendrite, directly stemming from the perikaryon, and carrying the dendritic spines.
|
2 | Q69ZK9 (/ISO) Q99K10 (/ISO) |
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
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2 | Q8BYM5 (/ISO) Q99K10 (/ISO) |
Excitatory synapse GO:0060076
A synapse in which an action potential in the presynaptic cell increases the probability of an action potential occurring in the postsynaptic cell.
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2 | Q69ZK9 (/ISO) Q8BYM5 (/ISO) |
Excitatory synapse GO:0060076
A synapse in which an action potential in the presynaptic cell increases the probability of an action potential occurring in the postsynaptic cell.
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2 | B0F2B4 (/ISS) Q8BYM5 (/ISS) |
Inhibitory synapse GO:0060077
A synapse in which an action potential in the presynaptic cell reduces the probability of an action potential occurring in the postsynaptic cell.
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2 | Q62889 (/IC) Q69ZK9 (/IC) |
Inhibitory synapse GO:0060077
A synapse in which an action potential in the presynaptic cell reduces the probability of an action potential occurring in the postsynaptic cell.
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2 | Q62888 (/IDA) Q62889 (/IDA) |
Inhibitory synapse GO:0060077
A synapse in which an action potential in the presynaptic cell reduces the probability of an action potential occurring in the postsynaptic cell.
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2 | Q69ZK9 (/ISO) Q8BYM5 (/ISO) |
Glycinergic synapse GO:0098690
A synapse that uses glycine as a neurotransmitter.
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2 | B0F2B4 (/IDA) Q69ZK9 (/IDA) |
Glycinergic synapse GO:0098690
A synapse that uses glycine as a neurotransmitter.
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2 | B0F2B4 (/IMP) Q69ZK9 (/IMP) |
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
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2 | Q8BYM5 (/ISO) Q99K10 (/ISO) |
GABA-ergic synapse GO:0098982
A synapse that uses GABA as a neurotransmitter. These synapses are typically inhibitory.
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2 | Q62888 (/IMP) Q69ZK9 (/IMP) |
GABA-ergic synapse GO:0098982
A synapse that uses GABA as a neurotransmitter. These synapses are typically inhibitory.
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2 | Q69ZK9 (/ISO) Q8BYM5 (/ISO) |
Integral component of postsynaptic membrane GO:0099055
The component of the postsynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
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2 | Q62888 (/IDA) Q62889 (/IDA) |
Integral component of postsynaptic membrane GO:0099055
The component of the postsynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
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2 | Q69ZK9 (/ISO) Q8BYM5 (/ISO) |
Integral component of postsynaptic specialization membrane GO:0099060
The component of the postsynaptic specialization membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
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2 | B0F2B4 (/IMP) Q62888 (/IMP) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
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1 | Q62888 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
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1 | Q69ZK9 (/ISO) |
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
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1 | Q62765 (/IDA) |
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
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1 | Q99K10 (/ISO) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
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1 | Q8N2Q7 (/ISS) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
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1 | Q99K10 (/IMP) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
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1 | Q8N2Q7 (/NAS) |
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
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1 | Q99K10 (/IDA) |
Postsynaptic density GO:0014069
An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
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1 | Q8N2Q7 (/TAS) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
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1 | Q8NFZ4 (/NAS) |
Endocytic vesicle GO:0030139
A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. Endocytic vesicles fuse with early endosomes to deliver the cargo for further sorting.
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1 | Q62889 (/IDA) |
Endocytic vesicle GO:0030139
A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. Endocytic vesicles fuse with early endosomes to deliver the cargo for further sorting.
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1 | Q8BYM5 (/ISO) |
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
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1 | Q99K10 (/ISO) |
Filopodium tip GO:0032433
The end of a filopodium distal to the body of the cell.
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1 | Q62765 (/IDA) |
Filopodium tip GO:0032433
The end of a filopodium distal to the body of the cell.
|
1 | Q99K10 (/ISO) |
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
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1 | Q62889 (/IDA) |
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
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1 | Q8BYM5 (/ISO) |
Dendritic spine GO:0043197
A small, membranous protrusion from a dendrite that forms a postsynaptic compartment - typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable including \thin\, \stubby\, \mushroom\, and \branched\, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.
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1 | Q62765 (/IDA) |
Dendritic spine GO:0043197
A small, membranous protrusion from a dendrite that forms a postsynaptic compartment - typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable including \thin\, \stubby\, \mushroom\, and \branched\, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.
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1 | Q99K10 (/ISO) |
Postsynaptic membrane GO:0045211
A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.
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1 | B0F2B4 (/IC) |
Postsynaptic membrane GO:0045211
A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.
|
1 | Q62888 (/IDA) |
Postsynaptic membrane GO:0045211
A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.
|
1 | Q69ZK9 (/ISO) |
Postsynaptic membrane GO:0045211
A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.
|
1 | Q8NFZ4 (/NAS) |
Excitatory synapse GO:0060076
A synapse in which an action potential in the presynaptic cell increases the probability of an action potential occurring in the postsynaptic cell.
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1 | Q8N2Q7 (/NAS) |
Inhibitory synapse GO:0060077
A synapse in which an action potential in the presynaptic cell reduces the probability of an action potential occurring in the postsynaptic cell.
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1 | Q8NFZ4 (/ISS) |
Ribbon synapse GO:0097470
Type of synapse characterized by an electron-dense ribbon, lamella (bar) or spherical body in the presynaptic process cytoplasm.
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1 | Q62888 (/IDA) |
Ribbon synapse GO:0097470
Type of synapse characterized by an electron-dense ribbon, lamella (bar) or spherical body in the presynaptic process cytoplasm.
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1 | Q69ZK9 (/ISO) |
Dopaminergic synapse GO:0098691
A synapse that uses dopamine as a neurotransmitter.
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1 | Q69ZK9 (/IDA) |
Postsynapse GO:0098794
The part of a synapse that is part of the post-synaptic cell.
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1 | Q8N2Q7 (/NAS) |
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
|
1 | Q99K10 (/IMP) |
Integral component of postsynaptic membrane GO:0099055
The component of the postsynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q8N2Q7 (/TAS) |