The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 60: tRNA (guanine-N(7)-)-methyltransferase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
TRNA (guanine-N7-)-methyltransferase activity GO:0008176
Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N7-methylguanine.
8 A9UMM1 (/ISS) Q23126 (/ISS) Q28H76 (/ISS) Q2YDF1 (/ISS) Q5XJ57 (/ISS) Q6NU94 (/ISS) Q6NU94 (/ISS) Q9Z120 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
7 Q12009 (/IPI) Q12009 (/IPI) Q12009 (/IPI) Q12009 (/IPI) Q12009 (/IPI) Q12009 (/IPI) Q9UBP6 (/IPI)
TRNA (guanine-N7-)-methyltransferase activity GO:0008176
Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N7-methylguanine.
1 Q9UBP6 (/IDA)
TRNA (guanine-N7-)-methyltransferase activity GO:0008176
Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N7-methylguanine.
1 Q9Z120 (/ISO)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
TRNA modification GO:0006400
The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.
8 A9UMM1 (/ISS) Q23126 (/ISS) Q28H76 (/ISS) Q2YDF1 (/ISS) Q5XJ57 (/ISS) Q6NU94 (/ISS) Q6NU94 (/ISS) Q9Z120 (/ISS)
TRNA modification GO:0006400
The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.
6 Q12009 (/TAS) Q12009 (/TAS) Q12009 (/TAS) Q12009 (/TAS) Q12009 (/TAS) Q12009 (/TAS)
TRNA (guanine-N7)-methylation GO:0106004
The process whereby a guanine in a tRNA is methylated at the N7 position of guanine.
6 Q12009 (/IDA) Q12009 (/IDA) Q12009 (/IDA) Q12009 (/IDA) Q12009 (/IDA) Q12009 (/IDA)
TRNA (guanine-N7)-methylation GO:0106004
The process whereby a guanine in a tRNA is methylated at the N7 position of guanine.
6 Q12009 (/IMP) Q12009 (/IMP) Q12009 (/IMP) Q12009 (/IMP) Q12009 (/IMP) Q12009 (/IMP)
TRNA modification GO:0006400
The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.
1 Q9UBP6 (/IDA)
TRNA modification GO:0006400
The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.
1 Q9Z120 (/ISO)

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
7 A9UMM1 (/ISS) Q28H76 (/ISS) Q2YDF1 (/ISS) Q5XJ57 (/ISS) Q6NU94 (/ISS) Q6NU94 (/ISS) Q9Z120 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 Q12009 (/HDA) Q12009 (/HDA) Q12009 (/HDA) Q12009 (/HDA) Q12009 (/HDA) Q12009 (/HDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
6 Q12009 (/TAS) Q12009 (/TAS) Q12009 (/TAS) Q12009 (/TAS) Q12009 (/TAS) Q12009 (/TAS)
TRNA (m7G46) methyltransferase complex GO:0106143
A protein complex involved in the catalysis of the formation of the modified nucleotide 7-methylguanine (at position 46 in certain tRNAs, such as tRNA(phe) and tRNA(met). In yeast, it is a heterotetramer of two subunits, Trm8 (catalytic) and Trm82 (WD repeat).
6 Q12009 (/IDA) Q12009 (/IDA) Q12009 (/IDA) Q12009 (/IDA) Q12009 (/IDA) Q12009 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9UBP6 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9Z120 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q9UBP6 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q9Z120 (/ISO)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
1 Q9UBP6 (/IDA)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
1 Q9Z120 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9UBP6 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9Z120 (/ISO)
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