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CATH Superfamily 3.40.50.12780

ANL, N-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
N-terminal domain of ligase-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Acetyl-coenzyme A synthetase

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Acetate--CoA ligase. [EC: 6.2.1.1]
ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.
  • Also acts on propanoate and propenoate.
 4910 A0A026V5M6 A0A026V5M6 A0A026V5M6 A0A026V5M6 A0A026V5M6 A0A026V5M6 A0A026V5M6 A0A026V5M6 A0A026V5M6 A0A026V5M6
(4900 more...)
Propionate--CoA ligase. [EC: 6.2.1.17]
ATP + propanoate + CoA = AMP + diphosphate + propanoyl-CoA.
  • Propenoate can act instead of propanoate.
  • Not identical with EC 6.2.1.1 or EC 6.2.1.2.
 111 A0A0D6HC33 A0A0D6HC33 A0A0D6HC33 A0A0D6HC33 A0A0D6HC33 A0A0D6HC33 A0A0D6HC33 A0A0D6HC33 A0A0D6HC33 A0A0D6HC33
(101 more...)
3-hydroxypropionyl-CoA synthase. [EC: 6.2.1.36]
3-hydroxypropanoate + ATP + CoA = 3-hydroxypropionyl-CoA + AMP + diphosphate.
  • Catalyzes a step in the 3-hydroxypropanoate/4-hydroxybutyrate cycle, an autotrophic CO(2) fixation pathway found in some thermoacidophilic archaea.
  • The enzymes from Metallosphaera sedula and Sulfolobus tokodaii can also use propanoate, acrylate, acetate, and butanoate as substrates, and are thus different from EC 6.2.1.17, which does not accept acetate or butanoate.
 5 A0A088E7D2 A0A088E7D2 A4YGR1 A4YGR1 Q973W5
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