View in Gene3D

CATH Superfamily 3.40.50.1220

TPP-binding domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
TPP-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 64: SIR2 family protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
 5 P0DN71 (/IDA) P0DN71 (/IDA) P0DN71 (/IDA) P0DN71 (/IDA) P0DN71 (/IDA)
NAD+ binding GO:0070403
Interacting selectively and non-covalently with the oxidized form, NAD, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions.
 5 P0DN71 (/IDA) P0DN71 (/IDA) P0DN71 (/IDA) P0DN71 (/IDA) P0DN71 (/IDA)
Protein ADP-ribosylase activity GO:1990404
The transfer, from NAD, of ADP-ribose to a protein amino acid residue.
 5 P0DN71 (/IDA) P0DN71 (/IDA) P0DN71 (/IDA) P0DN71 (/IDA) P0DN71 (/IDA)

There are 1 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein ADP-ribosylation GO:0006471
The transfer, from NAD, of ADP-ribose to protein amino acids.
 5 P0DN71 (/IDA) P0DN71 (/IDA) P0DN71 (/IDA) P0DN71 (/IDA) P0DN71 (/IDA)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.