The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"TPP-binding domain
".
FunFam 34: NAD-dependent histone deacetylase HST3
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Histone deacetylase activity GO:0004407
Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes.
|
1 | Q5A1W9 (/IMP) |
|
NAD-dependent histone deacetylase activity GO:0017136
Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from a histone.
|
1 | P53687 (/IDA) |
|
NAD-dependent histone deacetylase activity GO:0017136
Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from a histone.
|
1 | P53687 (/IMP) |
There are 11 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Chromatin silencing at telomere GO:0006348
Repression of transcription of telomeric DNA by altering the structure of chromatin.
|
1 | P53687 (/IGI) |
|
Histone deacetylation GO:0016575
The modification of histones by removal of acetyl groups.
|
1 | P53687 (/IGI) |
|
Histone deacetylation GO:0016575
The modification of histones by removal of acetyl groups.
|
1 | P53687 (/IMP) |
|
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
|
1 | Q5A1W9 (/IMP) |
|
Phenotypic switching GO:0036166
A reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations. Phenotypic switching involves changes in cell morphology and altered gene expression patterns. For example, Candida albicans switches from white cells to opaque cells for sexual mating. Phenotypic switching also occurs in multicellular organisms; smooth muscle cells (SMCs) exhibit phenotypic transitions to allow rapid adaption to fluctuating environmental cues.
|
1 | Q5A1W9 (/IMP) |
|
Filamentous growth of a population of unicellular organisms GO:0044182
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape.
|
1 | Q5A1W9 (/IMP) |
|
Short-chain fatty acid metabolic process GO:0046459
The chemical reactions and pathways involving fatty acids with a chain length of less than C6.
|
1 | P53687 (/IMP) |
|
Histone H3-K56 deacetylation GO:0071572
The modification of histone H3 by the removal of an acetyl group from lysine at position 56 of the histone.
|
1 | Q5A1W9 (/IMP) |
|
Regulation of phenotypic switching GO:1900239
Any process that modulates the frequency, rate or extent of phenotypic switching.
|
1 | Q5A1W9 (/IMP) |
|
Negative regulation of filamentous growth of a population of unicellular organisms GO:1900429
Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms.
|
1 | Q5A1W9 (/IMP) |
|
Replication-born double-strand break repair via sister chromatid exchange GO:1990414
The repair of a replication-born double-strand DNA break in which the DNA molecule is repaired using the homologous sequence of the sister chromatid which serves as a template to repair the breaks.
|
1 | P53687 (/IMP) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | P53687 (/IC) |