The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Leucine Dehydrogenase, chain A, domain 1
".
FunFam 12: Methylenetetrahydrofolate dehydrogenase [NAD(+)]
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Methylenetetrahydrofolate dehydrogenase (NAD+) activity GO:0004487
Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD(+) = 5,10-methenyltetrahydrofolate + NADH.
|
10 | Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) |
|
Methylenetetrahydrofolate dehydrogenase (NAD+) activity GO:0004487
Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD(+) = 5,10-methenyltetrahydrofolate + NADH.
|
2 | Q5BD56 (/RCA) Q5BD56 (/RCA) |
|
Methylenetetrahydrofolate dehydrogenase (NADP+) activity GO:0004488
Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH.
|
2 | Q5BD56 (/RCA) Q5BD56 (/RCA) |
|
Methylenetetrahydrofolate dehydrogenase (NAD+) activity GO:0004487
Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD(+) = 5,10-methenyltetrahydrofolate + NADH.
|
1 | Q9P786 (/ISO) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
One-carbon metabolic process GO:0006730
The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.
|
10 | Q02046 (/IDA) Q02046 (/IDA) Q02046 (/IDA) Q02046 (/IDA) Q02046 (/IDA) Q02046 (/IDA) Q02046 (/IDA) Q02046 (/IDA) Q02046 (/IDA) Q02046 (/IDA) |
|
One-carbon metabolic process GO:0006730
The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.
|
10 | Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) |
|
Purine nucleobase biosynthetic process GO:0009113
The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.
|
10 | Q02046 (/IDA) Q02046 (/IDA) Q02046 (/IDA) Q02046 (/IDA) Q02046 (/IDA) Q02046 (/IDA) Q02046 (/IDA) Q02046 (/IDA) Q02046 (/IDA) Q02046 (/IDA) |
|
Purine nucleobase biosynthetic process GO:0009113
The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.
|
10 | Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) |
|
Folic acid-containing compound biosynthetic process GO:0009396
The chemical reactions and pathways resulting in the formation of folic acid and its derivatives.
|
10 | Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) Q02046 (/IMP) |
|
One-carbon metabolic process GO:0006730
The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.
|
2 | Q5BD56 (/RCA) Q5BD56 (/RCA) |
|
Purine nucleobase biosynthetic process GO:0009113
The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.
|
1 | Q9P786 (/ISO) |
|
Folic acid biosynthetic process GO:0046656
The chemical reactions and pathways resulting in the formation of folic acid, pteroylglutamic acid.
|
1 | Q9P786 (/ISO) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
10 | Q02046 (/IDA) Q02046 (/IDA) Q02046 (/IDA) Q02046 (/IDA) Q02046 (/IDA) Q02046 (/IDA) Q02046 (/IDA) Q02046 (/IDA) Q02046 (/IDA) Q02046 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9P786 (/HDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9P786 (/HDA) |
