The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Toll/interleukin-1 receptor homology (TIR) domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 15: Toll/interleukin-1 receptor domain-containing adap...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 17 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 P58753 (/IPI) P58753 (/IPI) P58753 (/IPI) P58753 (/IPI) Q99JY1 (/IPI)
Toll-like receptor 2 binding GO:0035663
Interacting selectively and non-covalently with a Toll-like 2 protein, a pattern recognition receptor that binds microbial pattern motifs to initiate an innate immune response.
5 P58753 (/IPI) P58753 (/IPI) P58753 (/IPI) P58753 (/IPI) Q99JY1 (/IPI)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
5 P58753 (/IDA) P58753 (/IDA) P58753 (/IDA) P58753 (/IDA) Q99JY1 (/IDA)
Protein kinase C binding GO:0005080
Interacting selectively and non-covalently with protein kinase C.
4 P58753 (/IPI) P58753 (/IPI) P58753 (/IPI) P58753 (/IPI)
Phosphatidylinositol-4,5-bisphosphate binding GO:0005546
Interacting selectively and non-covalently with phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions.
4 P58753 (/ISS) P58753 (/ISS) P58753 (/ISS) P58753 (/ISS)
Protein binding, bridging GO:0030674
The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
4 P58753 (/NAS) P58753 (/NAS) P58753 (/NAS) P58753 (/NAS)
Toll-like receptor 4 binding GO:0035662
Interacting selectively and non-covalently with a Toll-like 4 protein, a pattern recognition receptor that binds bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
4 P58753 (/IPI) P58753 (/IPI) P58753 (/IPI) P58753 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
4 P58753 (/IPI) P58753 (/IPI) P58753 (/IPI) P58753 (/IPI)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
4 P58753 (/ISS) P58753 (/ISS) P58753 (/ISS) P58753 (/ISS)
Protein kinase C binding GO:0005080
Interacting selectively and non-covalently with protein kinase C.
1 Q99JY1 (/ISO)
Protein kinase C binding GO:0005080
Interacting selectively and non-covalently with protein kinase C.
1 Q99JY1 (/ISS)
Phosphatidylinositol-4,5-bisphosphate binding GO:0005546
Interacting selectively and non-covalently with phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions.
1 Q99JY1 (/IDA)
Toll-like receptor 4 binding GO:0035662
Interacting selectively and non-covalently with a Toll-like 4 protein, a pattern recognition receptor that binds bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
1 Q99JY1 (/ISO)
Toll-like receptor 2 binding GO:0035663
Interacting selectively and non-covalently with a Toll-like 2 protein, a pattern recognition receptor that binds microbial pattern motifs to initiate an innate immune response.
1 Q99JY1 (/ISO)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q99JY1 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 Q99JY1 (/IDA)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
1 Q99JY1 (/ISO)

There are 73 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of interleukin-8 production GO:0032757
Any process that activates or increases the frequency, rate, or extent of interleukin-8 production.
5 P58753 (/IMP) P58753 (/IMP) P58753 (/IMP) P58753 (/IMP) Q99JY1 (/IMP)
Positive regulation of tumor necrosis factor production GO:0032760
Any process that activates or increases the frequency, rate, or extent of tumor necrosis factor production.
5 P58753 (/IMP) P58753 (/IMP) P58753 (/IMP) P58753 (/IMP) Q99JY1 (/IMP)
Positive regulation of interleukin-6 biosynthetic process GO:0045410
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-6.
5 P58753 (/IMP) P58753 (/IMP) P58753 (/IMP) P58753 (/IMP) Q99JY1 (/IMP)
Positive regulation of NF-kappaB transcription factor activity GO:0051092
Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.
5 P58753 (/IMP) P58753 (/IMP) P58753 (/IMP) P58753 (/IMP) Q99JY1 (/IMP)
MyD88-dependent toll-like receptor signaling pathway GO:0002755
Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.
4 P58753 (/TAS) P58753 (/TAS) P58753 (/TAS) P58753 (/TAS)
Cell surface receptor signaling pathway GO:0007166
A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
4 P58753 (/ISS) P58753 (/ISS) P58753 (/ISS) P58753 (/ISS)
Activation of NF-kappaB-inducing kinase activity GO:0007250
The stimulation of the activity of NF-kappaB-inducing kinase through phosphorylation at specific residues.
4 P58753 (/IMP) P58753 (/IMP) P58753 (/IMP) P58753 (/IMP)
Myeloid cell differentiation GO:0030099
The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages.
4 P58753 (/ISS) P58753 (/ISS) P58753 (/ISS) P58753 (/ISS)
Positive regulation of B cell proliferation GO:0030890
Any process that activates or increases the rate or extent of B cell proliferation.
4 P58753 (/ISS) P58753 (/ISS) P58753 (/ISS) P58753 (/ISS)
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
4 P58753 (/IDA) P58753 (/IDA) P58753 (/IDA) P58753 (/IDA)
Regulation of interferon-beta production GO:0032648
Any process that modulates the frequency, rate, or extent of interferon-beta production.
4 P58753 (/ISS) P58753 (/ISS) P58753 (/ISS) P58753 (/ISS)
Positive regulation of interleukin-12 production GO:0032735
Any process that activates or increases the frequency, rate, or extent of interleukin-12 production.
4 P58753 (/ISS) P58753 (/ISS) P58753 (/ISS) P58753 (/ISS)
Positive regulation of interleukin-15 production GO:0032738
Any process that activates or increases the frequency, rate, or extent of interleukin-15 production.
4 P58753 (/IDA) P58753 (/IDA) P58753 (/IDA) P58753 (/IDA)
Positive regulation of toll-like receptor 2 signaling pathway GO:0034137
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 2 signaling pathway.
4 P58753 (/IMP) P58753 (/IMP) P58753 (/IMP) P58753 (/IMP)
Positive regulation of toll-like receptor 3 signaling pathway GO:0034141
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 3 signaling pathway.
4 P58753 (/ISS) P58753 (/ISS) P58753 (/ISS) P58753 (/ISS)
Positive regulation of toll-like receptor 4 signaling pathway GO:0034145
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway.
4 P58753 (/IMP) P58753 (/IMP) P58753 (/IMP) P58753 (/IMP)
TIRAP-dependent toll-like receptor 4 signaling pathway GO:0035665
Any series of molecular signals generated as a consequence of binding to a toll-like receptor 4 where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
4 P58753 (/IDA) P58753 (/IDA) P58753 (/IDA) P58753 (/IDA)
Positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123
Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling.
4 P58753 (/IMP) P58753 (/IMP) P58753 (/IMP) P58753 (/IMP)
Negative regulation of growth of symbiont in host GO:0044130
Any process in which the symbiont stops, prevents or reduces its increase in size or mass within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.
4 P58753 (/ISS) P58753 (/ISS) P58753 (/ISS) P58753 (/ISS)
Regulation of innate immune response GO:0045088
Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
4 P58753 (/IC) P58753 (/IC) P58753 (/IC) P58753 (/IC)
Positive regulation of JNK cascade GO:0046330
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the JNK cascade.
4 P58753 (/IMP) P58753 (/IMP) P58753 (/IMP) P58753 (/IMP)
Defense response to Gram-positive bacterium GO:0050830
Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.
4 P58753 (/ISS) P58753 (/ISS) P58753 (/ISS) P58753 (/ISS)
Positive regulation of ERK1 and ERK2 cascade GO:0070374
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
4 P58753 (/IMP) P58753 (/IMP) P58753 (/IMP) P58753 (/IMP)
3'-UTR-mediated mRNA stabilization GO:0070935
An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.
4 P58753 (/IDA) P58753 (/IDA) P58753 (/IDA) P58753 (/IDA)
Cellular response to bacterial lipopeptide GO:0071221
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus.
4 P58753 (/ISS) P58753 (/ISS) P58753 (/ISS) P58753 (/ISS)
Cellular response to lipoteichoic acid GO:0071223
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.
4 P58753 (/ISS) P58753 (/ISS) P58753 (/ISS) P58753 (/ISS)
Positive regulation of neutrophil chemotaxis GO:0090023
Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
4 P58753 (/ISS) P58753 (/ISS) P58753 (/ISS) P58753 (/ISS)
Positive regulation of protein homodimerization activity GO:0090073
Any process that increases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.
4 P58753 (/IDA) P58753 (/IDA) P58753 (/IDA) P58753 (/IDA)
Positive regulation of chemokine (C-X-C motif) ligand 1 production GO:2000340
Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.
4 P58753 (/ISS) P58753 (/ISS) P58753 (/ISS) P58753 (/ISS)
Positive regulation of chemokine (C-X-C motif) ligand 2 production GO:2000343
Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production.
4 P58753 (/ISS) P58753 (/ISS) P58753 (/ISS) P58753 (/ISS)
Cell surface receptor signaling pathway GO:0007166
A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
1 Q99JY1 (/IPI)
Cell surface receptor signaling pathway GO:0007166
A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
1 Q99JY1 (/ISO)
I-kappaB kinase/NF-kappaB signaling GO:0007249
The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.
1 Q99JY1 (/IMP)
I-kappaB kinase/NF-kappaB signaling GO:0007249
The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.
1 Q99JY1 (/ISO)
Activation of NF-kappaB-inducing kinase activity GO:0007250
The stimulation of the activity of NF-kappaB-inducing kinase through phosphorylation at specific residues.
1 Q99JY1 (/ISO)
Activation of JUN kinase activity GO:0007257
The initiation of the activity of the inactive enzyme JUN kinase (JNK).
1 Q99JY1 (/ISO)
Response to bacterium GO:0009617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
1 Q99JY1 (/ISO)
Myeloid cell differentiation GO:0030099
The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages.
1 Q99JY1 (/IMP)
Positive regulation of B cell proliferation GO:0030890
Any process that activates or increases the rate or extent of B cell proliferation.
1 Q99JY1 (/IMP)
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
1 Q99JY1 (/ISO)
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
1 Q99JY1 (/ISS)
Regulation of interferon-beta production GO:0032648
Any process that modulates the frequency, rate, or extent of interferon-beta production.
1 Q99JY1 (/IDA)
Regulation of interleukin-15 production GO:0032658
Any process that modulates the frequency, rate, or extent of interleukin-15 production.
1 Q99JY1 (/IMP)
Positive regulation of interleukin-12 production GO:0032735
Any process that activates or increases the frequency, rate, or extent of interleukin-12 production.
1 Q99JY1 (/IMP)
Positive regulation of interleukin-15 production GO:0032738
Any process that activates or increases the frequency, rate, or extent of interleukin-15 production.
1 Q99JY1 (/ISO)
Positive regulation of interleukin-8 production GO:0032757
Any process that activates or increases the frequency, rate, or extent of interleukin-8 production.
1 Q99JY1 (/ISO)
Positive regulation of tumor necrosis factor production GO:0032760
Any process that activates or increases the frequency, rate, or extent of tumor necrosis factor production.
1 Q99JY1 (/ISO)
Positive regulation of toll-like receptor 2 signaling pathway GO:0034137
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 2 signaling pathway.
1 Q99JY1 (/ISO)
Positive regulation of toll-like receptor 2 signaling pathway GO:0034137
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 2 signaling pathway.
1 Q99JY1 (/ISS)
Positive regulation of toll-like receptor 3 signaling pathway GO:0034141
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 3 signaling pathway.
1 Q99JY1 (/IDA)
Positive regulation of toll-like receptor 4 signaling pathway GO:0034145
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway.
1 Q99JY1 (/ISO)
Positive regulation of toll-like receptor 4 signaling pathway GO:0034145
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway.
1 Q99JY1 (/ISS)
TIRAP-dependent toll-like receptor 4 signaling pathway GO:0035665
Any series of molecular signals generated as a consequence of binding to a toll-like receptor 4 where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
1 Q99JY1 (/ISO)
Positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123
Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling.
1 Q99JY1 (/ISO)
Negative regulation of growth of symbiont in host GO:0044130
Any process in which the symbiont stops, prevents or reduces its increase in size or mass within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.
1 Q99JY1 (/IMP)
Regulation of innate immune response GO:0045088
Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
1 Q99JY1 (/NAS)
Positive regulation of innate immune response GO:0045089
Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
1 Q99JY1 (/IMP)
Positive regulation of interleukin-6 biosynthetic process GO:0045410
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-6.
1 Q99JY1 (/IDA)
Positive regulation of interleukin-6 biosynthetic process GO:0045410
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-6.
1 Q99JY1 (/ISO)
Positive regulation of JNK cascade GO:0046330
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the JNK cascade.
1 Q99JY1 (/ISO)
Positive regulation of JNK cascade GO:0046330
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the JNK cascade.
1 Q99JY1 (/ISS)
Defense response to Gram-positive bacterium GO:0050830
Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.
1 Q99JY1 (/IMP)
Positive regulation of NF-kappaB transcription factor activity GO:0051092
Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.
1 Q99JY1 (/ISO)
Positive regulation of ERK1 and ERK2 cascade GO:0070374
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
1 Q99JY1 (/ISO)
Positive regulation of ERK1 and ERK2 cascade GO:0070374
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
1 Q99JY1 (/ISS)
3'-UTR-mediated mRNA stabilization GO:0070935
An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.
1 Q99JY1 (/ISO)
3'-UTR-mediated mRNA stabilization GO:0070935
An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.
1 Q99JY1 (/ISS)
Cellular response to bacterial lipopeptide GO:0071221
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus.
1 Q99JY1 (/IMP)
Cellular response to lipoteichoic acid GO:0071223
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.
1 Q99JY1 (/IMP)
Positive regulation of neutrophil chemotaxis GO:0090023
Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
1 Q99JY1 (/IMP)
Positive regulation of protein homodimerization activity GO:0090073
Any process that increases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.
1 Q99JY1 (/ISO)
Positive regulation of chemokine (C-X-C motif) ligand 1 production GO:2000340
Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.
1 Q99JY1 (/IMP)
Positive regulation of chemokine (C-X-C motif) ligand 2 production GO:2000343
Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production.
1 Q99JY1 (/IMP)

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 P58753 (/IDA) P58753 (/IDA) P58753 (/IDA) P58753 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 P58753 (/TAS) P58753 (/TAS) P58753 (/TAS) P58753 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 P58753 (/IDA) P58753 (/IDA) P58753 (/IDA) P58753 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 P58753 (/TAS) P58753 (/TAS) P58753 (/TAS) P58753 (/TAS)
Endocytic vesicle GO:0030139
A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. Endocytic vesicles fuse with early endosomes to deliver the cargo for further sorting.
4 P58753 (/ISS) P58753 (/ISS) P58753 (/ISS) P58753 (/ISS)
Ruffle membrane GO:0032587
The portion of the plasma membrane surrounding a ruffle.
4 P58753 (/ISS) P58753 (/ISS) P58753 (/ISS) P58753 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q99JY1 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q99JY1 (/ISS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q99JY1 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q99JY1 (/ISS)
Endocytic vesicle GO:0030139
A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. Endocytic vesicles fuse with early endosomes to deliver the cargo for further sorting.
1 Q99JY1 (/IDA)
Ruffle membrane GO:0032587
The portion of the plasma membrane surrounding a ruffle.
1 Q99JY1 (/IDA)