The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Collagenase (Catalytic Domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1Neutral protease 2SC:2Matrix metallopeptidase 1672 kDa type IV collagenaseStromelysin-3 preproproteinMatrix metalloproteinase-14 preproproteinSC:3Calmodulin-sensitive adenylate cyclaseLethal factorSC:4Protein MtfASC:5A disintegrin and metalloproteinase with thrombospondin motifs 1disintegrin and metalloproteinase domain-containing protein 11Disintegrin and metalloproteinase domain-containing protein 17ArchaemetzincinSC:6Meprin A subunitMetalloendopeptidaseSerralysinAstacinSC:7endothelin-converting enzyme 1 isoform X1Probable zinc metalloproteaseDisintegrin and metalloproteinase domain-containing protein 22MetalloendopeptidaseThimet oligopeptidase 1Collagenase 3A disintegrin and metalloproteinase with thrombospondin motifs 3Oligopeptidase ADisintegrin and metalloproteinase domain-containing protein 10Mitochondrial intermediate peptidaseMatrix metallopeptidase 17Metalloendoproteinase 1Mitochondrial intermediate peptidase, mitochondrialMatrix metallopeptidase 28Matrix metalloproteinase 1, isoform CMatrix metallopeptidase 23Bendothelin-converting enzyme-like 1 isoform X1Pappalysin 1Matrix metallopeptidase 19Zinc metalloproteinaseMitochondrial intermediate peptidase 1MetalloendopeptidasePappalysin 2Probable thimet oligopeptidaseA disintegrin and metallopeptidase domain 18Sol narae, isoform CMatrix metallopeptidase 27MetalloendopeptidaseMetalloendopeptidaseMetalloendopeptidasePeptidase M3Kuzbanian-like, isoform AMetalloendopeptidaseMajor allergen Asp F2ADAM metallopeptidase with thrombospondin type 1 motif, 13MetalloendopeptidaseMatrix metallopeptidase 21Zinc metalloproteinaseKell blood group, metallo-endopeptidaseMetalloendopeptidaseADAM metallopeptidase domain 17Matrix metallopeptidase 26MetalloendopeptidaseBlast:Endothelin-converting enzyme 1Related to mitochondrial intermediate peptidaseThrombospondin type 1 domain proteinZinc metalloproteinaseMetalloendoproteinase 5-MMPOligopeptidase, putativeMitochondrial intermediate peptidase, putativeRelated to mitochondrial intermediate peptidaseZinc metalloproteinasePutative cytosolic oligopeptidase A-like ProteinMatrix metalloproteinase-CMetalloendopeptidaseMetalloendopeptidasePredicted proteinOligopeptidase AMatrix metallopeptidase 25bZinc metalloproteinaseMatrix metallopeptidase 25Zinc metalloproteinaseMetalloproteaseMetalloendopeptidasemembrane metallo-endopeptidase-like 1MetalloendopeptidaseMetalloendopeptidaseGone early, isoform BA disintegrin and metallopeptidase domain 30Serpentine receptor class gammaZinc metalloproteinaseZinc metalloproteinaseZinc metalloproteinaseDisintegrin and metalloproteinase domain-containing protein unc-71Uncharacterized protein, isoform AUncharacterized proteinDUF3152 domain-containing proteinneprilysinMatrix metalloproteinase-16-like ProteinStall, isoform CDisintegrin and metalloproteinase domain-containing protein BMeltrin, isoform DMetalloendopeptidaseOs10g0558125 proteinMetalloendopeptidaseMetalloendopeptidaseGM23611Oligopeptidase A, putativeMetalloendopeptidaseMatrix metalloproteinase 16Matrix metallopeptidase 21MetalloendopeptidaseZinc metalloproteinase nas-16MetalloendopeptidaseExtracellular metalloprotease 1A disintegrin and metallopeptidase domain 6Matrix metallopeptidase 19MetalloendopeptidaseMetalloendopeptidaseZinc MetalloProteaseMetalloendopeptidaseMetalloendopeptidaseMatrix metallopeptidase 30MetalloendopeptidaseMetalloendopeptidaseMetalloendopeptidaseProtein CBG24150Matrix metalloproteinase-BZinc metalloproteinaseMetalloendopeptidaseMatrix metalloproteinase 13Predicted proteinMetalloendopeptidaseA disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6MetalloendopeptidaseGD21387GG12482ADAM metallopeptidase domain 3AProtein CBG01792Matrix metallopeptidase 11bUncharacterized protein, isoform DMetalloendopeptidaseUncharacterized proteinMetalloendopeptidaseUncharacterized proteinZinc metalloproteinase nas-24MetalloendopeptidaseMetalloendopeptidasePeptidaseMetalloendopeptidaseLethal factorCarbohydrate-binding proteinMetalloendopeptidaseEndothelin-converting enzyme (AFU_orthologue AFUA_3G12420)Disintegrin and metalloproteinase domain-containing protein 5Matrix metallopeptidase 15aNeutral protease 2Matrix metalloproteinase-28-like ProteinMetalloendopeptidaseAGAP011870-PAMetalloendopeptidaseUncharacterized proteinMetalloendopeptidaseMetalloendopeptidaseMetalloendopeptidaseZinc metalloproteinaseFra mauro, isoform FUncharacterized proteinMetalloendopeptidaseNEPrilysin metallopeptidase family
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FunFam 172:

Representative CATH Domain E9GY39/1-27

Sequence alignment 200 sequences

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