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CATH Superfamily 3.40.1280.10

SPOUT methyltransferase, trefoil knot domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 41: tRNA (pseudouridine(54)-N(1))-methyltransferase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
TRNA (pseudouridine(54)-N(1))-methyltransferase. [EC: 2.1.1.257]
S-adenosyl-L-methionine + pseudouridine(54) in tRNA = S-adenosyl-L- homocysteine + N(1)-methylpseudouridine(54) in tRNA.
  • While this archaeal enzyme is specific for the 54 position and does not methylate pseudouridine at position 55, the presence of pseudouridine at position 55 is necessary for the efficient methylation of pseudouridine at position 54.
 11 B0R6T1 B0R6T1 D4GTL8 D4GTL8 L9VBV1 L9VBV1 Q59034 Q5JF45 Q8TQU1 Q9HNR6
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