The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Calcium-transporting ATPase, cytoplasmic domain N
".
FunFam 23: Copper-transporting ATPase 1, putative
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 19 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q04656 (/IPI) Q64430 (/IPI) |
Copper ion transmembrane transporter activity GO:0005375
Enables the transfer of copper (Cu) ions from one side of a membrane to the other.
|
1 | Q64430 (/IMP) |
Copper ion transmembrane transporter activity GO:0005375
Enables the transfer of copper (Cu) ions from one side of a membrane to the other.
|
1 | Q04656 (/ISS) |
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
|
1 | Q04656 (/IDA) |
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
|
1 | Q64430 (/ISO) |
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
|
1 | Q64430 (/ISS) |
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
1 | Q04656 (/TAS) |
Superoxide dismutase copper chaperone activity GO:0016532
A copper chaperone activity that specifically delivers copper to the Cu-Zn superoxide dismutase, to activate superoxide dismutase activity.
|
1 | Q64430 (/IDA) |
Superoxide dismutase copper chaperone activity GO:0016532
A copper chaperone activity that specifically delivers copper to the Cu-Zn superoxide dismutase, to activate superoxide dismutase activity.
|
1 | Q04656 (/ISS) |
Copper-dependent protein binding GO:0032767
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of copper.
|
1 | Q04656 (/IPI) |
Copper-dependent protein binding GO:0032767
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of copper.
|
1 | Q64430 (/ISO) |
Copper transmembrane transporter activity, phosphorylative mechanism GO:0043682
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cu2+(in) -> ADP + phosphate + Cu2+(out).
|
1 | Q64430 (/IDA) |
Copper transmembrane transporter activity, phosphorylative mechanism GO:0043682
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cu2+(in) -> ADP + phosphate + Cu2+(out).
|
1 | Q04656 (/ISS) |
Rac GTPase binding GO:0048365
Interacting selectively and non-covalently with Rac protein, any member of the Rac subfamily of the Ras superfamily of monomeric GTPases.
|
1 | P70705 (/IPI) |
Rac GTPase binding GO:0048365
Interacting selectively and non-covalently with Rac protein, any member of the Rac subfamily of the Ras superfamily of monomeric GTPases.
|
1 | Q64430 (/ISO) |
Chaperone binding GO:0051087
Interacting selectively and non-covalently with a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.
|
1 | P70705 (/IPI) |
Chaperone binding GO:0051087
Interacting selectively and non-covalently with a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.
|
1 | Q64430 (/ISO) |
Cuprous ion binding GO:1903136
Interacting selectively and non-covalently with cuprous ion, copper(1+).
|
1 | Q04656 (/IMP) |
Cuprous ion binding GO:1903136
Interacting selectively and non-covalently with cuprous ion, copper(1+).
|
1 | Q64430 (/ISO) |
There are 125 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Response to copper ion GO:0046688
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
|
5 | A0A2R8PXR4 (/IDA) F1Q5B3 (/IDA) F1QEG1 (/IDA) P70705 (/IDA) Q4F8H5 (/IDA) |
Response to metal ion GO:0010038
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.
|
4 | A0A2R8PXR4 (/IDA) F1Q5B3 (/IDA) F1QEG1 (/IDA) Q4F8H5 (/IDA) |
Response to copper ion GO:0046688
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
|
4 | A0A2R8PXR4 (/IMP) F1Q5B3 (/IMP) F1QEG1 (/IMP) Q4F8H5 (/IMP) |
Copper ion transport GO:0006825
The directed movement of copper (Cu) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
2 | Q04656 (/IMP) Q64430 (/IMP) |
Cellular copper ion homeostasis GO:0006878
Any process involved in the maintenance of an internal steady state of copper ions at the level of a cell.
|
2 | Q04656 (/IMP) Q64430 (/IMP) |
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
2 | P70705 (/IMP) Q64430 (/IMP) |
Copper ion export GO:0060003
The directed movement of copper ions out of a cell or organelle.
|
2 | P70705 (/IMP) Q64430 (/IMP) |
Blood vessel development GO:0001568
The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.
|
1 | Q64430 (/IMP) |
Blood vessel development GO:0001568
The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.
|
1 | Q04656 (/ISS) |
In utero embryonic development GO:0001701
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
|
1 | P70705 (/IEP) |
Release of cytochrome c from mitochondria GO:0001836
The process that results in the movement of cytochrome c from the mitochondrial intermembrane space into the cytosol, which is part of the apoptotic signaling pathway and leads to caspase activation.
|
1 | Q64430 (/IMP) |
Liver development GO:0001889
The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.
|
1 | P70705 (/IEP) |
Blood vessel remodeling GO:0001974
The reorganization or renovation of existing blood vessels.
|
1 | Q64430 (/IMP) |
Blood vessel remodeling GO:0001974
The reorganization or renovation of existing blood vessels.
|
1 | Q04656 (/ISS) |
Regulation of oxidative phosphorylation GO:0002082
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.
|
1 | Q64430 (/IMP) |
Regulation of oxidative phosphorylation GO:0002082
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.
|
1 | Q04656 (/ISS) |
Tryptophan metabolic process GO:0006568
The chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.
|
1 | Q64430 (/IMP) |
Tryptophan metabolic process GO:0006568
The chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.
|
1 | Q04656 (/ISS) |
Tyrosine metabolic process GO:0006570
The chemical reactions and pathways involving tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid.
|
1 | Q64430 (/IMP) |
Catecholamine metabolic process GO:0006584
The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.
|
1 | Q64430 (/IMP) |
Catecholamine metabolic process GO:0006584
The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.
|
1 | Q04656 (/ISS) |
Copper ion transport GO:0006825
The directed movement of copper (Cu) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q64430 (/IDA) |
Copper ion transport GO:0006825
The directed movement of copper (Cu) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q64430 (/ISO) |
Copper ion transport GO:0006825
The directed movement of copper (Cu) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q64430 (/ISS) |
Cellular copper ion homeostasis GO:0006878
Any process involved in the maintenance of an internal steady state of copper ions at the level of a cell.
|
1 | Q64430 (/IGI) |
Cellular copper ion homeostasis GO:0006878
Any process involved in the maintenance of an internal steady state of copper ions at the level of a cell.
|
1 | Q64430 (/ISO) |
Mitochondrion organization GO:0007005
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
|
1 | Q64430 (/IMP) |
Mitochondrion organization GO:0007005
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
|
1 | Q04656 (/ISS) |
Lactation GO:0007595
The regulated release of milk from the mammary glands and the period of time that a mother lactates to feed her young.
|
1 | P70705 (/IEP) |
Locomotory behavior GO:0007626
The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
|
1 | Q64430 (/IMP) |
Locomotory behavior GO:0007626
The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
|
1 | Q04656 (/ISS) |
Response to iron(III) ion GO:0010041
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(III) ion stimulus.
|
1 | P70705 (/IEP) |
Response to manganese ion GO:0010042
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus.
|
1 | P70705 (/IDA) |
Response to manganese ion GO:0010042
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus.
|
1 | P70705 (/IEP) |
Response to manganese ion GO:0010042
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus.
|
1 | Q64430 (/ISO) |
Response to zinc ion GO:0010043
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.
|
1 | P70705 (/IEP) |
Detoxification of copper ion GO:0010273
Any process that reduces or removes the toxicity of copper ion. These include transport of copper away from sensitive areas and to compartments or complexes whose purpose is sequestration of copper ion.
|
1 | Q64430 (/IMP) |
Detoxification of copper ion GO:0010273
Any process that reduces or removes the toxicity of copper ion. These include transport of copper away from sensitive areas and to compartments or complexes whose purpose is sequestration of copper ion.
|
1 | Q04656 (/ISS) |
Response to lead ion GO:0010288
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus.
|
1 | P70705 (/IEP) |
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | Q64430 (/ISO) |
Positive regulation of lamellipodium assembly GO:0010592
Any process that increases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
|
1 | P70705 (/IMP) |
Positive regulation of lamellipodium assembly GO:0010592
Any process that increases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
|
1 | Q64430 (/ISO) |
Copper ion import GO:0015677
The directed movement of copper ions into a cell or organelle.
|
1 | Q64430 (/IMP) |
Copper ion import GO:0015677
The directed movement of copper ions into a cell or organelle.
|
1 | Q04656 (/ISS) |
Peptidyl-lysine modification GO:0018205
The modification of peptidyl-lysine.
|
1 | Q64430 (/IMP) |
Peptidyl-lysine modification GO:0018205
The modification of peptidyl-lysine.
|
1 | Q04656 (/ISS) |
Removal of superoxide radicals GO:0019430
Any process, acting at the cellular level, involved in removing superoxide radicals (O2-) from a cell or organism, e.g. by conversion to dioxygen (O2) and hydrogen peroxide (H2O2).
|
1 | Q64430 (/IMP) |
Removal of superoxide radicals GO:0019430
Any process, acting at the cellular level, involved in removing superoxide radicals (O2-) from a cell or organism, e.g. by conversion to dioxygen (O2) and hydrogen peroxide (H2O2).
|
1 | Q04656 (/ISS) |
Antimicrobial humoral response GO:0019730
An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus.
|
1 | Q04656 (/TAS) |
Cerebellar Purkinje cell differentiation GO:0021702
The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Purkinje cell. Differentiation includes the processes involved in commitment of a neuroblast to a Purkinje cell fate. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem.
|
1 | Q64430 (/IMP) |
Cerebellar Purkinje cell differentiation GO:0021702
The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Purkinje cell. Differentiation includes the processes involved in commitment of a neuroblast to a Purkinje cell fate. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem.
|
1 | Q04656 (/ISS) |
Pyramidal neuron development GO:0021860
The progression of a pyramidal neuron from its initial formation to its mature state.
|
1 | Q64430 (/IMP) |
Pyramidal neuron development GO:0021860
The progression of a pyramidal neuron from its initial formation to its mature state.
|
1 | Q04656 (/ISS) |
Central nervous system neuron development GO:0021954
The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron.
|
1 | Q64430 (/IMP) |
Central nervous system neuron development GO:0021954
The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron.
|
1 | Q04656 (/ISS) |
Extracellular matrix organization GO:0030198
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.
|
1 | Q64430 (/IMP) |
Extracellular matrix organization GO:0030198
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.
|
1 | Q04656 (/ISS) |
Collagen fibril organization GO:0030199
Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix.
|
1 | Q64430 (/IMP) |
Collagen fibril organization GO:0030199
Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix.
|
1 | Q04656 (/ISS) |
Hair follicle morphogenesis GO:0031069
The process in which the anatomical structures of the hair follicle are generated and organized.
|
1 | Q64430 (/IMP) |
Hair follicle morphogenesis GO:0031069
The process in which the anatomical structures of the hair follicle are generated and organized.
|
1 | Q04656 (/ISS) |
Ion transmembrane transport GO:0034220
A process in which an ion is transported across a membrane.
|
1 | Q04656 (/TAS) |
Negative regulation of iron ion transmembrane transport GO:0034760
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
1 | P70705 (/IMP) |
Negative regulation of iron ion transmembrane transport GO:0034760
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
1 | Q64430 (/ISO) |
Cellular response to platelet-derived growth factor stimulus GO:0036120
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus.
|
1 | P70705 (/IMP) |
Cellular response to platelet-derived growth factor stimulus GO:0036120
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus.
|
1 | Q64430 (/ISO) |
T-helper cell differentiation GO:0042093
The process in which a relatively unspecialized thymocyte acquires specialized features of a T-helper cell.
|
1 | Q64430 (/IMP) |
T-helper cell differentiation GO:0042093
The process in which a relatively unspecialized thymocyte acquires specialized features of a T-helper cell.
|
1 | Q04656 (/ISS) |
Epinephrine metabolic process GO:0042414
The chemical reactions and pathways involving epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.
|
1 | Q64430 (/IMP) |
Epinephrine metabolic process GO:0042414
The chemical reactions and pathways involving epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.
|
1 | Q04656 (/ISS) |
Norepinephrine metabolic process GO:0042415
The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.
|
1 | Q64430 (/IMP) |
Norepinephrine metabolic process GO:0042415
The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.
|
1 | Q04656 (/ISS) |
Dopamine metabolic process GO:0042417
The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
|
1 | Q64430 (/IMP) |
Dopamine metabolic process GO:0042417
The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
|
1 | Q04656 (/ISS) |
Norepinephrine biosynthetic process GO:0042421
The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.
|
1 | Q64430 (/IMP) |
Serotonin metabolic process GO:0042428
The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.
|
1 | Q64430 (/IMP) |
Serotonin metabolic process GO:0042428
The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.
|
1 | Q04656 (/ISS) |
Positive regulation of catalytic activity GO:0043085
Any process that activates or increases the activity of an enzyme.
|
1 | Q64430 (/IMP) |
Positive regulation of catalytic activity GO:0043085
Any process that activates or increases the activity of an enzyme.
|
1 | Q04656 (/ISS) |
Negative regulation of catalytic activity GO:0043086
Any process that stops or reduces the activity of an enzyme.
|
1 | Q64430 (/IMP) |
Negative regulation of catalytic activity GO:0043086
Any process that stops or reduces the activity of an enzyme.
|
1 | Q04656 (/ISS) |
Pigmentation GO:0043473
The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells.
|
1 | Q64430 (/IMP) |
Pigmentation GO:0043473
The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells.
|
1 | Q04656 (/ISS) |
Negative regulation of neuron apoptotic process GO:0043524
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.
|
1 | Q64430 (/IMP) |
Skin development GO:0043588
The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue.
|
1 | Q64430 (/IMP) |
Skin development GO:0043588
The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue.
|
1 | Q04656 (/ISS) |
Positive regulation of cell size GO:0045793
Any process that increases cell size.
|
1 | P70705 (/IMP) |
Positive regulation of cell size GO:0045793
Any process that increases cell size.
|
1 | Q64430 (/ISO) |
ATP metabolic process GO:0046034
The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.
|
1 | Q64430 (/IMP) |
Response to copper ion GO:0046688
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
|
1 | P70705 (/IEP) |
Response to copper ion GO:0046688
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
|
1 | Q64430 (/ISO) |
Elastic fiber assembly GO:0048251
Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching.
|
1 | Q64430 (/IMP) |
Elastic fiber assembly GO:0048251
Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching.
|
1 | Q04656 (/ISS) |
Lung alveolus development GO:0048286
The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways.
|
1 | Q64430 (/IMP) |
Lung alveolus development GO:0048286
The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways.
|
1 | Q04656 (/ISS) |
Neuron projection morphogenesis GO:0048812
The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites.
|
1 | Q64430 (/IMP) |
Neuron projection morphogenesis GO:0048812
The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites.
|
1 | Q04656 (/ISS) |
Dendrite morphogenesis GO:0048813
The process in which the anatomical structures of a dendrite are generated and organized.
|
1 | Q64430 (/IMP) |
Positive regulation of epithelial cell proliferation GO:0050679
Any process that activates or increases the rate or extent of epithelial cell proliferation.
|
1 | P70705 (/IMP) |
Positive regulation of epithelial cell proliferation GO:0050679
Any process that activates or increases the rate or extent of epithelial cell proliferation.
|
1 | Q64430 (/ISO) |
Cartilage development GO:0051216
The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
|
1 | Q64430 (/IMP) |
Cartilage development GO:0051216
The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
|
1 | Q04656 (/ISS) |
Positive regulation of oxidoreductase activity GO:0051353
Any process that activates or increases the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.
|
1 | Q04656 (/IDA) |
Positive regulation of oxidoreductase activity GO:0051353
Any process that activates or increases the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.
|
1 | Q64430 (/ISO) |
Elastin biosynthetic process GO:0051542
The chemical reactions and pathways resulting in the formation of elastin, a fibrous glycoprotein found in elastic tissues such as the walls of arteries.
|
1 | Q64430 (/IMP) |
Elastin biosynthetic process GO:0051542
The chemical reactions and pathways resulting in the formation of elastin, a fibrous glycoprotein found in elastic tissues such as the walls of arteries.
|
1 | Q04656 (/ISS) |
Copper ion export GO:0060003
The directed movement of copper ions out of a cell or organelle.
|
1 | Q64430 (/ISO) |
Copper ion export GO:0060003
The directed movement of copper ions out of a cell or organelle.
|
1 | Q04656 (/ISS) |
Cellular response to amino acid stimulus GO:0071230
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
|
1 | P70705 (/IMP) |
Cellular response to amino acid stimulus GO:0071230
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
|
1 | Q64430 (/ISO) |
Cellular response to antibiotic GO:0071236
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
|
1 | P70705 (/IEP) |
Cellular response to cadmium ion GO:0071276
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
|
1 | P70705 (/IEP) |
Cellular response to cobalt ion GO:0071279
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus.
|
1 | P70705 (/IEP) |
Cellular response to copper ion GO:0071280
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
|
1 | P70705 (/IDA) |
Cellular response to copper ion GO:0071280
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
|
1 | P70705 (/IEP) |
Cellular response to copper ion GO:0071280
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
|
1 | Q64430 (/ISO) |
Cellular response to iron ion GO:0071281
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
|
1 | P70705 (/IEP) |
Cellular response to lead ion GO:0071284
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus.
|
1 | P70705 (/IEP) |
Cellular response to hypoxia GO:0071456
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
|
1 | P70705 (/IEP) |
Positive regulation of response to wounding GO:1903036
Any process that activates or increases the frequency, rate or extent of response to wounding.
|
1 | P70705 (/IMP) |
Positive regulation of response to wounding GO:1903036
Any process that activates or increases the frequency, rate or extent of response to wounding.
|
1 | Q64430 (/ISO) |
Positive regulation of vascular associated smooth muscle cell migration GO:1904754
Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell migration.
|
1 | P70705 (/IMP) |
Positive regulation of vascular associated smooth muscle cell migration GO:1904754
Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell migration.
|
1 | Q64430 (/ISO) |
Regulation of cytochrome-c oxidase activity GO:1904959
Any process that modulates the frequency, rate or extent of cytochrome-c oxidase activity.
|
1 | P70705 (/IMP) |
Regulation of cytochrome-c oxidase activity GO:1904959
Any process that modulates the frequency, rate or extent of cytochrome-c oxidase activity.
|
1 | Q64430 (/ISO) |
There are 45 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
|
3 | P70705 (/IDA) Q04656 (/IDA) Q64430 (/IDA) |
Trans-Golgi network GO:0005802
The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.
|
3 | P70705 (/IDA) Q04656 (/IDA) Q64430 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
3 | P70705 (/IDA) Q04656 (/IDA) Q64430 (/IDA) |
Late endosome GO:0005770
A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
|
2 | P70705 (/IDA) Q04656 (/IDA) |
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
|
2 | P70705 (/IDA) Q04656 (/IDA) |
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
2 | P70705 (/IDA) Q04656 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | P70705 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q64430 (/ISO) |
Late endosome GO:0005770
A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
|
1 | Q64430 (/ISO) |
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
1 | Q64430 (/ISO) |
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
|
1 | Q64430 (/ISO) |
Trans-Golgi network GO:0005802
The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.
|
1 | Q64430 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | P70705 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q64430 (/ISO) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q64430 (/ISO) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q04656 (/TAS) |
Microvillus GO:0005902
Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells.
|
1 | P70705 (/IDA) |
Microvillus GO:0005902
Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells.
|
1 | Q64430 (/ISO) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q04656 (/HDA) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q64430 (/IDA) |
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | P70705 (/IDA) |
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q64430 (/ISO) |
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
|
1 | Q64430 (/ISO) |
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
|
1 | P70705 (/IDA) |
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
|
1 | Q64430 (/ISO) |
Trans-Golgi network transport vesicle GO:0030140
A vesicle that mediates transport between the trans-Golgi network and other parts of the cell.
|
1 | Q04656 (/IMP) |
Trans-Golgi network transport vesicle GO:0030140
A vesicle that mediates transport between the trans-Golgi network and other parts of the cell.
|
1 | Q64430 (/ISO) |
Trans-Golgi network transport vesicle GO:0030140
A vesicle that mediates transport between the trans-Golgi network and other parts of the cell.
|
1 | Q64430 (/ISS) |
Secretory granule GO:0030141
A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
|
1 | P70705 (/IDA) |
Secretory granule GO:0030141
A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
|
1 | Q64430 (/ISO) |
Phagocytic vesicle membrane GO:0030670
The lipid bilayer surrounding a phagocytic vesicle.
|
1 | Q04656 (/TAS) |
Cell leading edge GO:0031252
The area of a motile cell closest to the direction of movement.
|
1 | P70705 (/IDA) |
Cell leading edge GO:0031252
The area of a motile cell closest to the direction of movement.
|
1 | Q64430 (/ISO) |
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
|
1 | Q64430 (/IDA) |
Brush border membrane GO:0031526
The portion of the plasma membrane surrounding the brush border.
|
1 | P70705 (/IDA) |
Brush border membrane GO:0031526
The portion of the plasma membrane surrounding the brush border.
|
1 | Q64430 (/ISO) |
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
|
1 | Q64430 (/IDA) |
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
|
1 | Q04656 (/ISS) |
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
|
1 | Q64430 (/IDA) |
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
|
1 | Q04656 (/ISS) |
Perikaryon GO:0043204
The portion of the cell soma (neuronal cell body) that excludes the nucleus.
|
1 | P70705 (/IDA) |
Perikaryon GO:0043204
The portion of the cell soma (neuronal cell body) that excludes the nucleus.
|
1 | Q64430 (/ISO) |
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
|
1 | P70705 (/IDA) |
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
|
1 | Q64430 (/ISO) |
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
1 | Q64430 (/ISO) |