The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Carbonic anhydrase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Carbonic anhydrase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Carbonate dehydratase activity GO:0004089
Catalysis of the reaction: H2CO3 = CO2 + H2O.
168 P45148 (/IDA) P45148 (/IDA) P45148 (/IDA) P45148 (/IDA) P45148 (/IDA) P45148 (/IDA) P45148 (/IDA) P45148 (/IDA) P45148 (/IDA) P45148 (/IDA)
(158 more)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
168 P45148 (/IDA) P45148 (/IDA) P45148 (/IDA) P45148 (/IDA) P45148 (/IDA) P45148 (/IDA) P45148 (/IDA) P45148 (/IDA) P45148 (/IDA) P45148 (/IDA)
(158 more)
Carbonate dehydratase activity GO:0004089
Catalysis of the reaction: H2CO3 = CO2 + H2O.
145 P61517 (/TAS) P61517 (/TAS) P61517 (/TAS) P61517 (/TAS) P61517 (/TAS) P61517 (/TAS) P61517 (/TAS) P61517 (/TAS) P61517 (/TAS) P61517 (/TAS)
(135 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
145 P61517 (/IPI) P61517 (/IPI) P61517 (/IPI) P61517 (/IPI) P61517 (/IPI) P61517 (/IPI) P61517 (/IPI) P61517 (/IPI) P61517 (/IPI) P61517 (/IPI)
(135 more)
Carbonate dehydratase activity GO:0004089
Catalysis of the reaction: H2CO3 = CO2 + H2O.
8 Q9KUD6 (/ISS) Q9KUD6 (/ISS) Q9KUD6 (/ISS) Q9KUD6 (/ISS) Q9KUD6 (/ISS) Q9KUD6 (/ISS) Q9KUD6 (/ISS) Q9KUD6 (/ISS)
Carbonate dehydratase activity GO:0004089
Catalysis of the reaction: H2CO3 = CO2 + H2O.
1 O94255 (/ISO)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Carbon utilization GO:0015976
A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbon sources and then activates genes to scavenge the last traces of the primary carbon source and to transport and metabolize alternative carbon sources such as carbon dioxide or carbonic acid. The utilization process begins when the cell or organism detects carbon levels, includes the activation of genes whose products detect, transport or metabolize carbon-containing substances, and ends when carbon is incorporated into the cell or organism's metabolism.
12 P45148 (/IDA) P45148 (/IDA) P45148 (/IDA) P45148 (/IDA) P45148 (/IDA) P45148 (/IDA) P45148 (/IDA) P45148 (/IDA) P45148 (/IDA) P45148 (/IDA)
(2 more)
One-carbon metabolic process GO:0006730
The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.
1 O94255 (/IC)
Cellular detoxification GO:1990748
Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.
1 O94255 (/IC)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
145 P61517 (/HDA) P61517 (/HDA) P61517 (/HDA) P61517 (/HDA) P61517 (/HDA) P61517 (/HDA) P61517 (/HDA) P61517 (/HDA) P61517 (/HDA) P61517 (/HDA)
(135 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
145 P61517 (/IDA) P61517 (/IDA) P61517 (/IDA) P61517 (/IDA) P61517 (/IDA) P61517 (/IDA) P61517 (/IDA) P61517 (/IDA) P61517 (/IDA) P61517 (/IDA)
(135 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 O94255 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 O94255 (/ISO)
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