The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Repressor of RNA polymerase III transcription Maf1
".
FunFam 2: Repressor of RNA polymerase III transcription MAF1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
RNA polymerase III type 1 promoter DNA binding GO:0001030
Interacting selectively and non-covalently with a region of DNA that is a part of a type 1 promoter that controls transcription by RNA polymerase III. Type 1 promoters are found in 5S rRNA genes, downstream of the transcription start site within the sequence of the mature RNA, and require TFIIIA for recognition.
|
3 | Q9H063 (/IDA) Q9H063 (/IDA) Q9H063 (/IDA) |
|
RNA polymerase III type 2 promoter DNA binding GO:0001031
Interacting selectively and non-covalently with a region of DNA that is a part of a type 2 promoter that controls transcription by RNA polymerase III. Type 2 promoters consist of an A box and a B box downstream of the transcription start site within the sequence within the sequence of the mature RNA. Type 2 promoters are found in many tRNA genes as well as in other small RNAs.
|
3 | Q9H063 (/IDA) Q9H063 (/IDA) Q9H063 (/IDA) |
|
RNA polymerase III type 3 promoter DNA binding GO:0001032
Interacting selectively and non-covalently with a region of DNA that is a part of a type 3 promoter that controls transcription by RNA polymerase III. A type 3 Pol III promoter is composed of elements upstream of the transcription start site, including a TATA box. The human U6 snRNA gene has a type 3 promoter. Type 3 Pol III promoters have not been observed in S. cerevisiae.
|
3 | Q9H063 (/IDA) Q9H063 (/IDA) Q9H063 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | Q9H063 (/IPI) Q9H063 (/IPI) Q9H063 (/IPI) |
There are 2 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of transcription by RNA polymerase III GO:0016480
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase III.
|
4 | A5D9C6 (/ISS) A5D9C6 (/ISS) Q6PGU2 (/ISS) Q7ZWL6 (/ISS) |
|
Negative regulation of transcription by RNA polymerase III GO:0016480
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase III.
|
3 | Q9H063 (/IDA) Q9H063 (/IDA) Q9H063 (/IDA) |
There are 9 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
5 | E9PR76 (/IDA) E9PSH4 (/IDA) Q9H063 (/IDA) Q9H063 (/IDA) Q9H063 (/IDA) |
|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
5 | E9PR76 (/IDA) E9PSH4 (/IDA) Q9H063 (/IDA) Q9H063 (/IDA) Q9H063 (/IDA) |
|
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
|
5 | E9PR76 (/IDA) E9PSH4 (/IDA) Q9H063 (/IDA) Q9H063 (/IDA) Q9H063 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
4 | A5D9C6 (/ISS) A5D9C6 (/ISS) Q6PGU2 (/ISS) Q7ZWL6 (/ISS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | A5D9C6 (/ISS) A5D9C6 (/ISS) Q6PGU2 (/ISS) Q7ZWL6 (/ISS) |
|
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
|
3 | Q9H063 (/IDA) Q9H063 (/IDA) Q9H063 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
3 | Q9H063 (/TAS) Q9H063 (/TAS) Q9H063 (/TAS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
3 | Q9H063 (/IDA) Q9H063 (/IDA) Q9H063 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
3 | Q9H063 (/TAS) Q9H063 (/TAS) Q9H063 (/TAS) |
