The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Bira Bifunctional Protein; Domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 16: Asparagine--tRNA ligase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Asparagine-tRNA ligase activity GO:0004816
Catalysis of the reaction: L-asparagine + ATP + tRNA(Asn) = AMP + Asn-tRNA(Asn) + diphosphate + 2 H(+).
166 O96198 (/IDA) O96198 (/IDA) O96198 (/IDA) O96198 (/IDA) O96198 (/IDA) O96198 (/IDA) O96198 (/IDA) O96198 (/IDA) O96198 (/IDA) O96198 (/IDA)
(156 more)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
146 P0A8M0 (/IMP) P0A8M0 (/IMP) P0A8M0 (/IMP) P0A8M0 (/IMP) P0A8M0 (/IMP) P0A8M0 (/IMP) P0A8M0 (/IMP) P0A8M0 (/IMP) P0A8M0 (/IMP) P0A8M0 (/IMP)
(136 more)
Asparagine-tRNA ligase activity GO:0004816
Catalysis of the reaction: L-asparagine + ATP + tRNA(Asn) = AMP + Asn-tRNA(Asn) + diphosphate + 2 H(+).
15 O48593 (/ISS) P25345 (/ISS) P25345 (/ISS) P25345 (/ISS) P25345 (/ISS) P25345 (/ISS) P25345 (/ISS) P25345 (/ISS) Q55FI3 (/ISS) Q9KSF9 (/ISS)
(5 more)
TRNA binding GO:0000049
Interacting selectively and non-covalently with transfer RNA.
1 Q9P6I0 (/IC)
Asparagine-tRNA ligase activity GO:0004816
Catalysis of the reaction: L-asparagine + ATP + tRNA(Asn) = AMP + Asn-tRNA(Asn) + diphosphate + 2 H(+).
1 Q9P6I0 (/ISO)
Asparagine-tRNA ligase activity GO:0004816
Catalysis of the reaction: L-asparagine + ATP + tRNA(Asn) = AMP + Asn-tRNA(Asn) + diphosphate + 2 H(+).
1 Q7JZR5 (/TAS)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 Q9P6I0 (/ISM)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Asparaginyl-tRNA aminoacylation GO:0006421
The process of coupling asparagine to asparaginyl-tRNA, catalyzed by asparaginyl-tRNA synthetase. The asparaginyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of an asparagine-accetping tRNA.
166 O96198 (/IDA) O96198 (/IDA) O96198 (/IDA) O96198 (/IDA) O96198 (/IDA) O96198 (/IDA) O96198 (/IDA) O96198 (/IDA) O96198 (/IDA) O96198 (/IDA)
(156 more)
TRNA aminoacylation for protein translation GO:0006418
The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, to be used in ribosome-mediated polypeptide synthesis.
146 P0A8M0 (/IDA) P0A8M0 (/IDA) P0A8M0 (/IDA) P0A8M0 (/IDA) P0A8M0 (/IDA) P0A8M0 (/IDA) P0A8M0 (/IDA) P0A8M0 (/IDA) P0A8M0 (/IDA) P0A8M0 (/IDA)
(136 more)
Asparaginyl-tRNA aminoacylation GO:0006421
The process of coupling asparagine to asparaginyl-tRNA, catalyzed by asparaginyl-tRNA synthetase. The asparaginyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of an asparagine-accetping tRNA.
15 O48593 (/ISS) P25345 (/ISS) P25345 (/ISS) P25345 (/ISS) P25345 (/ISS) P25345 (/ISS) P25345 (/ISS) P25345 (/ISS) Q55FI3 (/ISS) Q9KSF9 (/ISS)
(5 more)
Mitochondrial asparaginyl-tRNA aminoacylation GO:0070145
The process of coupling asparagine to asparaginyl-tRNA in a mitochondrion, catalyzed by asparaginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
7 P25345 (/IMP) P25345 (/IMP) P25345 (/IMP) P25345 (/IMP) P25345 (/IMP) P25345 (/IMP) P25345 (/IMP)
Asparaginyl-tRNA aminoacylation GO:0006421
The process of coupling asparagine to asparaginyl-tRNA, catalyzed by asparaginyl-tRNA synthetase. The asparaginyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of an asparagine-accetping tRNA.
1 Q9P6I0 (/ISO)
Asparaginyl-tRNA aminoacylation GO:0006421
The process of coupling asparagine to asparaginyl-tRNA, catalyzed by asparaginyl-tRNA synthetase. The asparaginyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of an asparagine-accetping tRNA.
1 Q7JZR5 (/TAS)
Embryo development ending in seed dormancy GO:0009793
The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.
1 Q9SW96 (/IMP)
Mitochondrial translation GO:0032543
The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.
1 Q9P6I0 (/NAS)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
1 Q9SW96 (/IEP)
Plant ovule development GO:0048481
The process whose specific outcome is the progression of the ovule over time, from its formation to the mature structure. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed.
1 O48593 (/IMP)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
8 P25345 (/HDA) P25345 (/HDA) P25345 (/HDA) P25345 (/HDA) P25345 (/HDA) P25345 (/HDA) P25345 (/HDA) Q9P6I0 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
7 P25345 (/IMP) P25345 (/IMP) P25345 (/IMP) P25345 (/IMP) P25345 (/IMP) P25345 (/IMP) P25345 (/IMP)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
5 O51128 (/IDA) O51128 (/IDA) Q9SSK1 (/IDA) Q9SSK1 (/IDA) Q9SW96 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 O48593 (/IDA) Q9SW96 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 O48593 (/ISS) Q55FI3 (/ISS)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
2 O48593 (/IDA) Q9SW96 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P54263 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q7JZR5 (/TAS)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
1 Q9P6I0 (/IC)
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
1 O48593 (/IDA)
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