The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
2-Layer Sandwich
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Phosphatidylinositol 4-phosphate 5-kinase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
1-phosphatidylinositol-4-phosphate 5-kinase activity GO:0016308
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ADP + 2 H(+).
8 O48709 (/IDA) Q56YP2 (/IDA) Q56YP2 (/IDA) Q8L796 (/IDA) Q8L796 (/IDA) Q9SFB8 (/IDA) Q9SFB8 (/IDA) Q9SFB8 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 Q8L796 (/IPI) Q8L796 (/IPI) Q8L850 (/IPI)
Actin monomer binding GO:0003785
Interacting selectively and non-covalently with monomeric actin, also known as G-actin.
2 Q56YP2 (/IDA) Q56YP2 (/IDA)
Phosphatidylinositol phosphate kinase activity GO:0016307
Catalysis of the reaction: ATP + a phosphatidylinositol phosphate = ADP + a phosphatidylinositol bisphosphate.
2 Q56YP2 (/IDA) Q56YP2 (/IDA)
Actin filament binding GO:0051015
Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
2 Q56YP2 (/IDA) Q56YP2 (/IDA)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Clathrin-dependent endocytosis GO:0072583
An endocytosis process that begins when material is taken up into clathrin-coated pits, which then pinch off to form clathrin-coated endocytic vesicles.
3 Q9SFB8 (/IMP) Q9SFB8 (/IMP) Q9SFB8 (/IMP)
Developmental process involved in reproduction GO:0003006
A developmental process in which a progressive change in the state of some part of an organism specifically contributes to its ability to form offspring.
2 Q8L796 (/IMP) Q8L796 (/IMP)
Positive gravitropism GO:0009958
The orientation of plant parts towards gravity.
2 Q8L796 (/IMP) Q8L796 (/IMP)
Lateral root formation GO:0010311
The process that gives rise to a lateral root. This process pertains to the initial formation of a structure from unspecified parts. A lateral root primordium represents an organized group of cells derived from the root pericycle that will differentiate into a new root, as opposed to the initiation of the main root from the embryo proper.
2 Q8L796 (/IMP) Q8L796 (/IMP)
Carbohydrate metabolic process GO:0005975
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
1 Q8L850 (/IMP)
Cellular amino acid metabolic process GO:0006520
The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
1 Q8L850 (/IMP)
Root hair initiation GO:0048766
The process in which a protrusion or bulge is formed at the site of plant root hair outgrowth.
1 O48709 (/IMP)
Root hair elongation GO:0048767
The process in which the root hair grows longer.
1 O48709 (/IMP)
Root hair cell tip growth GO:0048768
Localized growth of a plant root hair tip by extension of the cell wall.
1 O48709 (/IMP)
Regulation of establishment of cell polarity GO:2000114
Any process that modulates the frequency, rate or extent of establishment of cell polarity.
1 O48709 (/IMP)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
7 F4HRM3 (/IDA) O48709 (/IDA) Q56YP2 (/IDA) Q56YP2 (/IDA) Q8L796 (/IDA) Q8L796 (/IDA) Q9SUI2 (/IDA)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
4 O48709 (/IDA) Q9SFB8 (/IDA) Q9SFB8 (/IDA) Q9SFB8 (/IDA)
Pollen tube GO:0090406
A tubular cell projection that is part of a pollen tube cell and extends from a pollen grain.
3 Q9SFB8 (/IDA) Q9SFB8 (/IDA) Q9SFB8 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q8L850 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 O48709 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q8L850 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q8L850 (/IDA)
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