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CATH Superfamily 3.30.760.10

RNA Cap, Translation Initiation Factor Eif4e

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
RNA Cap, Translation Initiation Factor Eif4e
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Eukaryotic translation initiation factor 4E type 2...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 13 O60573 (/IPI) O60573 (/IPI) O60573 (/IPI) O60573 (/IPI) O60573 (/IPI) O60573 (/IPI) O60573 (/IPI) O60573 (/IPI) O60573 (/IPI) O60573 (/IPI)
(3 more)
RNA cap binding GO:0000339
Interacting selectively and non-covalently with a 7-methylguanosine (m7G) group or derivative located at the 5' end of an RNA molecule.
 12 O60573 (/TAS) O60573 (/TAS) O60573 (/TAS) O60573 (/TAS) O60573 (/TAS) O60573 (/TAS) O60573 (/TAS) O60573 (/TAS) O60573 (/TAS) O60573 (/TAS)
(2 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
 12 O60573 (/HDA) O60573 (/HDA) O60573 (/HDA) O60573 (/HDA) O60573 (/HDA) O60573 (/HDA) O60573 (/HDA) O60573 (/HDA) O60573 (/HDA) O60573 (/HDA)
(2 more)
Translation factor activity, RNA binding GO:0008135
Functions during translation by interacting selectively and non-covalently with RNA during polypeptide synthesis at the ribosome.
 12 O60573 (/TAS) O60573 (/TAS) O60573 (/TAS) O60573 (/TAS) O60573 (/TAS) O60573 (/TAS) O60573 (/TAS) O60573 (/TAS) O60573 (/TAS) O60573 (/TAS)
(2 more)
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
 12 O60573 (/IPI) O60573 (/IPI) O60573 (/IPI) O60573 (/IPI) O60573 (/IPI) O60573 (/IPI) O60573 (/IPI) O60573 (/IPI) O60573 (/IPI) O60573 (/IPI)
(2 more)
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
 1 Q8BMB3 (/ISO)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of translation GO:0017148
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
 12 O60573 (/IMP) O60573 (/IMP) O60573 (/IMP) O60573 (/IMP) O60573 (/IMP) O60573 (/IMP) O60573 (/IMP) O60573 (/IMP) O60573 (/IMP) O60573 (/IMP)
(2 more)
In utero embryonic development GO:0001701
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
 1 Q8BMB3 (/IMP)
Negative regulation of translation GO:0017148
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
 1 Q8BMB3 (/ISO)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 12 O60573 (/TAS) O60573 (/TAS) O60573 (/TAS) O60573 (/TAS) O60573 (/TAS) O60573 (/TAS) O60573 (/TAS) O60573 (/TAS) O60573 (/TAS) O60573 (/TAS)
(2 more)
MRNA cap binding complex GO:0005845
Any protein complex that binds to an mRNA cap at any time in the lifetime of the mRNA.
 12 O60573 (/IDA) O60573 (/IDA) O60573 (/IDA) O60573 (/IDA) O60573 (/IDA) O60573 (/IDA) O60573 (/IDA) O60573 (/IDA) O60573 (/IDA) O60573 (/IDA)
(2 more)
MRNA cap binding complex GO:0005845
Any protein complex that binds to an mRNA cap at any time in the lifetime of the mRNA.
 1 Q8BMB3 (/ISO)
MRNA cap binding complex GO:0005845
Any protein complex that binds to an mRNA cap at any time in the lifetime of the mRNA.
 1 Q8BMB3 (/ISS)
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