The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 949: Uncharacterized protein, isoform A
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phosphatidylinositol-3-phosphatase activity GO:0004438
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3-phosphate + H2O = 1-phosphatidyl-1D-myo-inositol + phosphate.
|
1 | Q5U0V7 (/ISS) |
|
Phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity GO:0004439
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate.
|
1 | Q5U0V7 (/ISS) |
|
Phosphatidylinositol phosphate 5-phosphatase activity GO:0034595
Catalysis of the removal of the 5-phosphate group of a phosphatidylinositol phosphate.
|
1 | Q5U0V7 (/ISS) |
|
Phosphatidylinositol-4-phosphate phosphatase activity GO:0043812
Catalysis of the reaction: phosphatidylinositol-4-phosphate + H2O = phosphatidylinositol + orthophosphate.
|
1 | Q5U0V7 (/ISS) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Synaptic vesicle endocytosis GO:0048488
A vesicle-mediated transport process, in which the synaptic vesicle membrane constituents are retrieved from the presynaptic membrane on the axon terminal after neurotransmitter secretion by exocytosis. Synaptic vesicle endocytosis can occur via clathrin-dependent and clathrin-independent mechanisms.
|
2 | Q5U0V7 (/IMP) Q8MR94 (/IMP) |
|
Maintenance of presynaptic active zone structure GO:0048790
A process which maintains the organization and the arrangement of proteins at the active zone to ensure the fusion and docking of vesicles and the release of neurotransmitters.
|
2 | Q5U0V7 (/IMP) Q8MR94 (/IMP) |
|
Regulation of synapse structure or activity GO:0050803
Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
|
2 | Q5U0V7 (/IMP) Q8MR94 (/IMP) |
|
Phosphatidylinositol dephosphorylation GO:0046856
The process of removing one or more phosphate groups from a phosphatidylinositol.
|
1 | Q5U0V7 (/ISS) |
|
Clathrin-dependent synaptic vesicle endocytosis GO:0150007
Clathrin-dependent endocytosis of presynaptic membrane regions comprising synaptic vesicles' membrane constituents. This is a relatively slow process occurring in the range of tens of seconds.
|
1 | Q5U0V7 (/IMP) |
|
Bulk synaptic vesicle endocytosis GO:0150008
Endocytosis of large regions of presynaptic membrane after intense stimulation-mediated fusion of multiple synaptic vesicles. Bulk endocytosis is triggered by high loads of membrane addition through exocytosis of synaptic vesicles and elevated concentration of calcium in the presynapse.
|
1 | Q5U0V7 (/IMP) |
|
Positive regulation of autophagosome assembly GO:2000786
Any process that activates or increases the frequency, rate or extent of autophagic vacuole assembly.
|
1 | Q5U0V7 (/IMP) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Autophagosome GO:0005776
A double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the lytic vacuole/lysosome for degradation as part of macroautophagy.
|
1 | Q5U0V7 (/IDA) |
|
Vesicle membrane GO:0012506
The lipid bilayer surrounding any membrane-bounded vesicle in the cell.
|
1 | Q5U0V7 (/IDA) |
|
Terminal bouton GO:0043195
Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.
|
1 | Q5U0V7 (/IDA) |
|
Autolysosome GO:0044754
A type of secondary lysosome in which a primary lysosome has fused with the outer membrane of an autophagosome. It is involved in the second step of autophagy in which it degrades contents with acidic lysosomal hydrolases.
|
1 | Q5U0V7 (/IDA) |
|
Type I terminal bouton GO:0061174
Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters that will induce the contraction of muscle. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.
|
1 | Q5U0V7 (/IDA) |
