The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 648: Polyadenylate-binding protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
3 Q38E63 (/ISA) Q38E63 (/ISA) Q38E63 (/ISA)
Poly(A) binding GO:0008143
Interacting selectively and non-covalently with a sequence of adenylyl residues in an RNA molecule, such as the poly(A) tail, a sequence of adenylyl residues at the 3' end of eukaryotic mRNA.
3 E9AFX7 (/IDA) Q05196 (/IDA) Q05196 (/IDA)
Poly(A) binding GO:0008143
Interacting selectively and non-covalently with a sequence of adenylyl residues in an RNA molecule, such as the poly(A) tail, a sequence of adenylyl residues at the 3' end of eukaryotic mRNA.
3 Q38E63 (/ISA) Q38E63 (/ISA) Q38E63 (/ISA)
Eukaryotic initiation factor 4E binding GO:0008190
Interacting selectively and non-covalently with eukaryotic initiation factor 4E, a polypeptide factor involved in the initiation of ribosome-mediated translation.
1 E9AFX7 (/IPI)
Eukaryotic initiation factor 4G binding GO:0031370
Interacting selectively and non-covalently with eukaryotic initiation factor 4G, a polypeptide factor involved in the initiation of ribosome-mediated translation.
1 E9AFX7 (/IDA)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA processing GO:0006396
Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
3 Q38E63 (/ISA) Q38E63 (/ISA) Q38E63 (/ISA)
Regulation of translational initiation GO:0006446
Any process that modulates the frequency, rate or extent of translational initiation.
3 Q38E63 (/ISA) Q38E63 (/ISA) Q38E63 (/ISA)
Posttranscriptional regulation of gene expression GO:0010608
Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript.
3 Q38E63 (/IDA) Q38E63 (/IDA) Q38E63 (/IDA)
Nuclear-transcribed mRNA poly(A) tail shortening GO:0000289
Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length.
2 Q05196 (/IGI) Q05196 (/IGI)
Translational initiation GO:0006413
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
2 Q05196 (/IGI) Q05196 (/IGI)
MRNA polyadenylation GO:0006378
The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.
1 E9AFX7 (/IDA)
MRNA processing GO:0006397
Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
1 O64380 (/IGI)
Regulation of nuclear-transcribed mRNA poly(A) tail shortening GO:0060211
Any process that modulates the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.
1 O64380 (/IDA)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 E9AFX7 (/IDA) Q38E63 (/IDA) Q38E63 (/IDA) Q38E63 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 E9AFX7 (/ISO) Q38E63 (/ISO) Q38E63 (/ISO) Q38E63 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 E9AFX7 (/IDA) Q05196 (/IDA) Q05196 (/IDA)
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
3 Q38E63 (/IDA) Q38E63 (/IDA) Q38E63 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q05196 (/IDA) Q05196 (/IDA)
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
1 E9AFX7 (/ISO)
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