The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 37: RNA-binding protein with multiple splicing 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 16 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
18 |
E9QHK7 (/IPI)
G5ECJ4 (/IPI)
Q6ZRY4 (/IPI)
Q7ZUL7 (/IPI)
Q93062 (/IPI)
Q93062 (/IPI)
Q93062 (/IPI)
Q93062 (/IPI)
Q93062 (/IPI)
Q93062 (/IPI)
(8 more) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
16 |
Q6ZRY4 (/IPI)
Q93062 (/IPI)
Q93062 (/IPI)
Q93062 (/IPI)
Q93062 (/IPI)
Q93062 (/IPI)
Q93062 (/IPI)
Q93062 (/IPI)
Q93062 (/IPI)
Q93062 (/IPI)
(6 more) |
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
14 |
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
(4 more) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
14 |
Q93062 (/HDA)
Q93062 (/HDA)
Q93062 (/HDA)
Q93062 (/HDA)
Q93062 (/HDA)
Q93062 (/HDA)
Q93062 (/HDA)
Q93062 (/HDA)
Q93062 (/HDA)
Q93062 (/HDA)
(4 more) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
14 |
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
(4 more) |
|
Poly(A) binding GO:0008143
Interacting selectively and non-covalently with a sequence of adenylyl residues in an RNA molecule, such as the poly(A) tail, a sequence of adenylyl residues at the 3' end of eukaryotic mRNA.
|
14 |
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
(4 more) |
|
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
|
5 | E9QHK7 (/IDA) Q6ZRY4 (/IDA) Q7ZUL7 (/IDA) Q9ASW4 (/IDA) Q9W6I1 (/IDA) |
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
4 | Q9W6I1 (/ISS) Q9WVB0 (/ISS) Q9YGP5 (/ISS) Q9YGP5 (/ISS) |
|
Poly(A) binding GO:0008143
Interacting selectively and non-covalently with a sequence of adenylyl residues in an RNA molecule, such as the poly(A) tail, a sequence of adenylyl residues at the 3' end of eukaryotic mRNA.
|
4 | Q9W6I1 (/ISS) Q9WVB0 (/ISS) Q9YGP5 (/ISS) Q9YGP5 (/ISS) |
|
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
|
2 | Q01617 (/ISS) Q01617 (/ISS) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
2 | Q8VC52 (/ISO) Q9WVB0 (/ISO) |
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
1 | Q9WVB0 (/ISO) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | Q9WVB0 (/ISO) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | Q9WVB0 (/ISS) |
|
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
|
1 | Q8VC52 (/ISO) |
|
Poly(A) binding GO:0008143
Interacting selectively and non-covalently with a sequence of adenylyl residues in an RNA molecule, such as the poly(A) tail, a sequence of adenylyl residues at the 3' end of eukaryotic mRNA.
|
1 | Q9WVB0 (/ISO) |
There are 35 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
RNA processing GO:0006396
Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
|
14 |
Q93062 (/TAS)
Q93062 (/TAS)
Q93062 (/TAS)
Q93062 (/TAS)
Q93062 (/TAS)
Q93062 (/TAS)
Q93062 (/TAS)
Q93062 (/TAS)
Q93062 (/TAS)
Q93062 (/TAS)
(4 more) |
|
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
14 |
Q93062 (/IMP)
Q93062 (/IMP)
Q93062 (/IMP)
Q93062 (/IMP)
Q93062 (/IMP)
Q93062 (/IMP)
Q93062 (/IMP)
Q93062 (/IMP)
Q93062 (/IMP)
Q93062 (/IMP)
(4 more) |
|
Positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862
Any process that increases the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.
|
14 |
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
(4 more) |
|
Positive regulation of SMAD protein signal transduction GO:0060391
Any process that increases the rate, frequency or extent of SMAD protein signal transduction. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.
|
14 |
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
(4 more) |
|
Positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862
Any process that increases the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.
|
4 | Q9W6I1 (/ISS) Q9WVB0 (/ISS) Q9YGP5 (/ISS) Q9YGP5 (/ISS) |
|
Negative regulation of BMP signaling pathway GO:0030514
Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
|
4 | Q6ZRY4 (/ISS) Q8VC52 (/ISS) Q9YGP5 (/ISS) Q9YGP5 (/ISS) |
|
Retinal ganglion cell axon guidance GO:0031290
The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
|
4 | E9QHK7 (/IGI) Q6DH13 (/IGI) Q6DH13 (/IGI) Q7ZUL7 (/IGI) |
|
Embryonic digestive tract morphogenesis GO:0048557
The process in which the anatomical structures of the digestive tract are generated and organized during embryonic development. The digestive tract is the anatomical structure through which food passes and is processed.
|
4 | Q6ZRY4 (/ISS) Q8VC52 (/ISS) Q9YGP5 (/ISS) Q9YGP5 (/ISS) |
|
Positive regulation of smooth muscle cell proliferation GO:0048661
Any process that activates or increases the rate or extent of smooth muscle cell proliferation.
|
4 | Q6ZRY4 (/ISS) Q8VC52 (/ISS) Q9YGP5 (/ISS) Q9YGP5 (/ISS) |
|
Dendrite morphogenesis GO:0048813
The process in which the anatomical structures of a dendrite are generated and organized.
|
4 | E9QHK7 (/IGI) Q6DH13 (/IGI) Q6DH13 (/IGI) Q7ZUL7 (/IGI) |
|
Negative regulation of smooth muscle cell differentiation GO:0051151
Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation.
|
4 | Q6ZRY4 (/ISS) Q8VC52 (/ISS) Q9YGP5 (/ISS) Q9YGP5 (/ISS) |
|
Positive regulation of SMAD protein signal transduction GO:0060391
Any process that increases the rate, frequency or extent of SMAD protein signal transduction. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.
|
4 | Q9W6I1 (/ISS) Q9WVB0 (/ISS) Q9YGP5 (/ISS) Q9YGP5 (/ISS) |
|
Regulation of retinal ganglion cell axon guidance GO:0090259
Any process that modulates the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
|
4 | E9QHK7 (/IGI) Q6DH13 (/IGI) Q6DH13 (/IGI) Q7ZUL7 (/IGI) |
|
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
|
2 | Q01617 (/IMP) Q01617 (/IMP) |
|
Dormancy process GO:0022611
A developmental process in which dormancy (sometimes called a dormant state) is induced, maintained or broken. Dormancy is a suspension of most physiological activity and growth that can be reactivated.
|
2 | Q01617 (/IMP) Q01617 (/IMP) |
|
Regulation of hemocyte proliferation GO:0035206
Any process that modulates the frequency, rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster.
|
2 | Q01617 (/IMP) Q01617 (/IMP) |
|
Negative regulation of smooth muscle cell differentiation GO:0051151
Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation.
|
2 | Q6ZRY4 (/IMP) Q9W6I1 (/IMP) |
|
Nematode larval development GO:0002119
The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.
|
1 | G5ECJ4 (/IMP) |
|
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
1 | Q9WVB0 (/ISO) |
|
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
1 | Q9WVB0 (/ISS) |
|
Mechanosensory behavior GO:0007638
Behavior that is dependent upon the sensation of a mechanical stimulus.
|
1 | G5ECJ4 (/IMP) |
|
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
|
1 | G5ECJ4 (/IGI) |
|
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
|
1 | G5ECJ4 (/IMP) |
|
Positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862
Any process that increases the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.
|
1 | Q9WVB0 (/ISO) |
|
Erythrocyte differentiation GO:0030218
The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.
|
1 | E7F9Q3 (/IMP) |
|
Negative regulation of BMP signaling pathway GO:0030514
Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
|
1 | Q9W6I1 (/IMP) |
|
Hemidesmosome assembly GO:0031581
Assembly of hemidesmosomes, integrin-containing protein complexes that bind to laminin in the basal lamina. Hemidesmosomes form the contact between the basal surface of epithelial cells and the underlying basal lamina.
|
1 | G5ECJ4 (/IGI) |
|
Embryonic digestive tract morphogenesis GO:0048557
The process in which the anatomical structures of the digestive tract are generated and organized during embryonic development. The digestive tract is the anatomical structure through which food passes and is processed.
|
1 | Q9W6I1 (/IMP) |
|
Digestive tract development GO:0048565
The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed.
|
1 | Q9W6I1 (/IMP) |
|
Muscle organ morphogenesis GO:0048644
The process in which the anatomical structures of muscle are generated and organized.
|
1 | G5ECJ4 (/IGI) |
|
Muscle organ morphogenesis GO:0048644
The process in which the anatomical structures of muscle are generated and organized.
|
1 | G5ECJ4 (/IMP) |
|
Positive regulation of smooth muscle cell proliferation GO:0048661
Any process that activates or increases the rate or extent of smooth muscle cell proliferation.
|
1 | Q9W6I1 (/IMP) |
|
Neuron development GO:0048666
The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
|
1 | G5ECJ4 (/IMP) |
|
Negative regulation of smooth muscle cell differentiation GO:0051151
Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation.
|
1 | Q8VC52 (/ISO) |
|
Positive regulation of SMAD protein signal transduction GO:0060391
Any process that increases the rate, frequency or extent of SMAD protein signal transduction. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.
|
1 | Q9WVB0 (/ISO) |
There are 11 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
15 |
B4E3T4 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
(5 more) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
15 |
B4E3T4 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
(5 more) |
|
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
|
14 |
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
Q93062 (/IDA)
(4 more) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | Q8VC52 (/ISS) Q9W6I1 (/ISS) Q9YGP5 (/ISS) Q9YGP5 (/ISS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | G5ECJ4 (/IDA) Q01617 (/IDA) Q01617 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q9WVB0 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q6ZRY4 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q8VC52 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9WVB0 (/ISO) |
|
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
|
1 | Q9WVB0 (/ISO) |
|
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
|
1 | Q9WVB0 (/ISS) |
